den Boer AT - Search Results

1

Importance of weight loss maintenance and risk prediction in the prevention of type 2 diabetes: analysis of European Diabetes Prevention Study RCT.

Penn L, White M, Lindström J, den Boer AT, Blaak E, Eriksson JG, Feskens E, Ilanne-Parikka P, Keinänen-Kiukaanniemi SM, Walker M, Mathers JC, Uusitupa M, Tuomilehto J. Penn L, et al. Among authors: den boer at. PLoS One. 2013;8(2):e57143. doi: 10.1371/journal.pone.0057143. Epub 2013 Feb 25. PLoS One. 2013. PMID: 23451166 Free PMC article. Clinical Trial.

2

Prevention of the metabolic syndrome in IGT subjects in a lifestyle intervention: results from the SLIM study.

den Boer AT, Herraets IJ, Stegen J, Roumen C, Corpeleijn E, Schaper NC, Feskens E, Blaak EE. den Boer AT, et al. Nutr Metab Cardiovasc Dis. 2013 Nov;23(11):1147-53. doi: 10.1016/j.numecd.2012.12.005. Epub 2013 Feb 23. Nutr Metab Cardiovasc Dis. 2013. PMID: 23462149 Free article. Clinical Trial.

3

Monocytes, but not T cells, respond to insulin with Akt(S473) phosphorylation independent of the donor glucometabolic state.

Thewissen MM, van de Gaar J, den Boer AT, Munsters MJ, Blaak EE, Duijvestijn A. Thewissen MM, et al. Among authors: den boer at. Diabetes Metab Res Rev. 2014 May;30(4):323-32. doi: 10.1002/dmrr.2498. Diabetes Metab Res Rev. 2014. PMID: 24302564

4

CD4+ T cells are able to promote tumor growth through inhibition of tumor-specific CD8+ T-cell responses in tumor-bearing hosts.

den Boer AT, van Mierlo GJ, Fransen MF, Melief CJ, Offringa R, Toes RE. den Boer AT, et al. Cancer Res. 2005 Aug 1;65(15):6984-9. doi: 10.1158/0008-5472.CAN-04-3344. Cancer Res. 2005. PMID: 16061684

5

In vivo triggering through 4-1BB enables Th-independent priming of CTL in the presence of an intact CD28 costimulatory pathway.

Diehl L, van Mierlo GJ, den Boer AT, van der Voort E, Fransen M, van Bostelen L, Krimpenfort P, Melief CJ, Mittler R, Toes RE, Offringa R. Diehl L, et al. Among authors: den boer at. J Immunol. 2002 Apr 15;168(8):3755-62. doi: 10.4049/jimmunol.168.8.3755. J Immunol. 2002. PMID: 11937526

6

CD40 stimulation leads to effective therapy of CD40(-) tumors through induction of strong systemic cytotoxic T lymphocyte immunity.

van Mierlo GJ, den Boer AT, Medema JP, van der Voort EI, Fransen MF, Offringa R, Melief CJ, Toes RE. van Mierlo GJ, et al. Among authors: den boer at. Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5561-6. doi: 10.1073/pnas.082107699. Epub 2002 Apr 2. Proc Natl Acad Sci U S A. 2002. PMID: 11929985 Free PMC article.

7

The tumoricidal activity of memory CD8+ T cells is hampered by persistent systemic antigen, but full functional capacity is regained in an antigen-free environment.

den Boer AT, van Mierlo GJ, Fransen MF, Melief CJ, Offringa R, Toes RE. den Boer AT, et al. J Immunol. 2004 May 15;172(10):6074-9. doi: 10.4049/jimmunol.172.10.6074. J Immunol. 2004. PMID: 15128791

8

Activation of dendritic cells that cross-present tumor-derived antigen licenses CD8+ CTL to cause tumor eradication.

van Mierlo GJ, Boonman ZF, Dumortier HM, den Boer AT, Fransen MF, Nouta J, van der Voort EI, Offringa R, Toes RE, Melief CJ. van Mierlo GJ, et al. Among authors: den boer at. J Immunol. 2004 Dec 1;173(11):6753-9. doi: 10.4049/jimmunol.173.11.6753. J Immunol. 2004. PMID: 15557168

9

CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T-lymphocyte tolerance and augments anti-tumor vaccine efficacy.

Diehl L, den Boer AT, Schoenberger SP, van der Voort EI, Schumacher TN, Melief CJ, Offringa R, Toes RE. Diehl L, et al. Among authors: den boer at. Nat Med. 1999 Jul;5(7):774-9. doi: 10.1038/10495. Nat Med. 1999. PMID: 10395322

10

Successful immunotherapy of an intraocular tumor in mice.

Schurmans LR, den Boer AT, Diehl L, van der Voort EI, Kast WM, Melief CJ, Toes RE, Jager MJ. Schurmans LR, et al. Among authors: den boer at. Cancer Res. 1999 Oct 15;59(20):5250-4. Cancer Res. 1999. PMID: 10537305

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