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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1968 1
1972 1
1974 1
1975 1
1979 1
1981 1
1982 2
1983 3
1984 1
1985 5
1986 3
1987 4
1988 8
1989 2
1990 9
1991 5
1992 7
1993 7
1994 11
1995 5
1996 5
1997 7
1998 11
1999 13
2000 6
2001 16
2002 9
2003 12
2004 10
2005 20
2006 23
2007 26
2008 14
2009 34
2010 33
2011 47
2012 40
2013 70
2014 108
2015 121
2016 146
2017 168
2018 185
2019 191
2020 232
2021 240
2022 244
2023 232
2024 100

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2,162 results

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Page 1
Dimethyl Fumarate Delays Multiple Sclerosis in Radiologically Isolated Syndrome.
Okuda DT, Kantarci O, Lebrun-Frénay C, Sormani MP, Azevedo CJ, Bovis F, Hua LH, Amezcua L, Mowry EM, Hotermans C, Mendoza J, Walsh JS, von Hehn C, Vargas WS, Donlon S, Naismith RT, Okai A, Pardo G, Repovic P, Stüve O, Siva A, Pelletier D. Okuda DT, et al. Ann Neurol. 2023 Mar;93(3):604-614. doi: 10.1002/ana.26555. Epub 2022 Dec 10. Ann Neurol. 2023. PMID: 36401339 Clinical Trial.
Within 12 MS centers in the United States, participants were randomly assigned 1:1 to oral dimethyl fumarate (DMF) 240 mg twice daily or placebo. The primary endpoint was the time to onset of clinical symptoms attributable to a CNS demyelinating event within a follo …
Within 12 MS centers in the United States, participants were randomly assigned 1:1 to oral dimethyl fumarate (DMF) 240 mg twic …
Dimethyl Fumarate: A Review in Relapsing-Remitting MS.
Blair HA. Blair HA. Drugs. 2019 Dec;79(18):1965-1976. doi: 10.1007/s40265-019-01229-3. Drugs. 2019. PMID: 31784875 Review.
Dimethyl fumarate (Tecfidera()) is approved for the treatment of relapsing forms of multiple sclerosis (MS). ...Thus twice-daily dimethyl fumarate remains an effective treatment option for use in patients with RRMS, with the convenience of oral adminis
Dimethyl fumarate (Tecfidera()) is approved for the treatment of relapsing forms of multiple sclerosis (MS). ...Thus twice-dai
Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity.
Kornberg MD, Bhargava P, Kim PM, Putluri V, Snowman AM, Putluri N, Calabresi PA, Snyder SH. Kornberg MD, et al. Science. 2018 Apr 27;360(6387):449-453. doi: 10.1126/science.aan4665. Epub 2018 Mar 29. Science. 2018. PMID: 29599194 Free PMC article.
Activated immune cells undergo a metabolic switch to aerobic glycolysis akin to the Warburg effect, thereby presenting a potential therapeutic target in autoimmune disease. Dimethyl fumarate (DMF), a derivative of the Krebs cycle intermediate fumarate, is an …
Activated immune cells undergo a metabolic switch to aerobic glycolysis akin to the Warburg effect, thereby presenting a potential therapeut …
Dimethyl Fumarate and Intestine: From Main Suspect to Potential Ally against Gut Disorders.
Manai F, Zanoletti L, Arfini D, Micco SG, Gjyzeli A, Comincini S, Amadio M. Manai F, et al. Int J Mol Sci. 2023 Jun 8;24(12):9912. doi: 10.3390/ijms24129912. Int J Mol Sci. 2023. PMID: 37373057 Free PMC article. Review.
Dimethyl fumarate (DMF) is a well-characterized molecule that exhibits immuno-modulatory, anti-inflammatory, and antioxidant properties and that is currently approved for the treatment of psoriasis and multiple sclerosis. ...
Dimethyl fumarate (DMF) is a well-characterized molecule that exhibits immuno-modulatory, anti-inflammatory, and antioxidant p
Dimethyl fumarate protects against hepatic ischemia-reperfusion injury by alleviating ferroptosis via the NRF2/SLC7A11/HO-1 axis.
Qi D, Chen P, Bao H, Zhang L, Sun K, Song S, Li T. Qi D, et al. Cell Cycle. 2023 Apr;22(7):818-828. doi: 10.1080/15384101.2022.2155016. Epub 2022 Dec 8. Cell Cycle. 2023. PMID: 36482709 Free PMC article.
Dimethyl fumarate (DMF), a therapeutic agent for relapsing-remitting multiple sclerosis, has cytoprotective and antioxidant effects. ...
Dimethyl fumarate (DMF), a therapeutic agent for relapsing-remitting multiple sclerosis, has cytoprotective and antioxidant ef
Dimethyl fumarate: A review of preclinical efficacy in models of neurodegenerative diseases.
Majkutewicz I. Majkutewicz I. Eur J Pharmacol. 2022 Jul 5;926:175025. doi: 10.1016/j.ejphar.2022.175025. Epub 2022 May 13. Eur J Pharmacol. 2022. PMID: 35569547 Free article. Review.
Dimethyl fumarate (DMF) is an antioxidative and anti-inflammatory drug approved for treatment of multiple sclerosis and psoriasis; however, beneficial effects of DMF have also been found in other inflammatory diseases and cancers. DMF is a prodrug that is immediatel
Dimethyl fumarate (DMF) is an antioxidative and anti-inflammatory drug approved for treatment of multiple sclerosis and psoria
Dimethyl fumarate-associated ashy dermatosis.
Burlando M, Salvi I, Guadagno A, Cozzani E, Parodi A. Burlando M, et al. J Dtsch Dermatol Ges. 2022 Nov;20(11):1502-1504. doi: 10.1111/ddg.14889. Epub 2022 Nov 10. J Dtsch Dermatol Ges. 2022. PMID: 36354064 No abstract available.
Dimethyl fumarate induced migrating polyarthralgias.
Villedon de Naide M, Moisset X, Soubrier M. Villedon de Naide M, et al. Joint Bone Spine. 2019 May;86(3):399-400. doi: 10.1016/j.jbspin.2018.07.006. Epub 2018 Aug 3. Joint Bone Spine. 2019. PMID: 30081200 Review. No abstract available.
Delayed and recurrent dimethyl fumarate induced-lymphopenia in patients with multiple sclerosis.
Borrelli S, Mathias A, Goff GL, Pasquier RD, Théaudin M, Pot C. Borrelli S, et al. Mult Scler Relat Disord. 2022 Jul;63:103887. doi: 10.1016/j.msard.2022.103887. Epub 2022 May 15. Mult Scler Relat Disord. 2022. PMID: 35636269 Review.
To better understand these specific aspects, we reviewed cases that develop prolonged grade 2 to 4 lymphopenia under dimethyl fumarate in Lausanne MS clinic. METHOD: Retrospective analysis of the 12 patients (10.1%) who discontinued dimethyl fumarate b …
To better understand these specific aspects, we reviewed cases that develop prolonged grade 2 to 4 lymphopenia under dimethyl fuma
Dimethyl fumarate induced lymphopenia in multiple sclerosis: A review of the literature.
Dello Russo C, Scott KA, Pirmohamed M. Dello Russo C, et al. Pharmacol Ther. 2021 Mar;219:107710. doi: 10.1016/j.pharmthera.2020.107710. Epub 2020 Oct 20. Pharmacol Ther. 2021. PMID: 33091427 Review.
Dimethyl fumarate (DMF) is a first line medication for multiple sclerosis. ...Understanding the molecular mechanisms underlying DMF action is challenging: in vivo DMF is rapidly metabolized to monomethyl fumarate (MMF), a less potent immunomodulator in vitro.
Dimethyl fumarate (DMF) is a first line medication for multiple sclerosis. ...Understanding the molecular mechanisms underlyin
2,162 results