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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 3
1964 1
1965 1
1967 1
1972 1
1974 2
1975 2
1976 3
1977 2
1978 4
1979 6
1980 6
1981 5
1982 5
1983 8
1984 8
1985 1
1987 2
1988 2
1989 5
1991 1
1992 1
1993 4
1994 6
1995 1
1996 2
1997 1
1998 3
1999 5
2000 1
2001 3
2002 2
2003 2
2004 4
2005 2
2006 7
2007 14
2008 4
2009 4
2010 6
2011 4
2012 7
2013 9
2014 9
2015 6
2016 4
2017 6
2018 4
2019 4
2020 1
2021 6
2022 9
2023 7
2024 0

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202 results

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Page 1
Drotaverine-induced priapism.
Kanbur AS, Agarwal A, Rokade ML. Kanbur AS, et al. Indian J Urol. 2021 Jan-Mar;37(1):90-91. doi: 10.4103/iju.IJU_240_20. Epub 2021 Jan 1. Indian J Urol. 2021. PMID: 33850364 Free PMC article.
Drug-induced priapism is well known and papaverine is the most common drug known to cause priapism. Drotaverine, an analog of papaverine, is used extensively to treat Colicky pain. We report the first case of drotaverine.induced priapism....
Drug-induced priapism is well known and papaverine is the most common drug known to cause priapism. Drotaverine, an analog of papaver …
Drotaverine to shorten the duration of labour in primigravidas: a randomised, double-blind, placebo-controlled trial.
Ikeotuonye AC, Umeora OJ, Nwafor JI, Ojumah BO, Ekwunife IC, Dimejesi IB. Ikeotuonye AC, et al. Afr Health Sci. 2022 Sep;22(3):108-116. doi: 10.4314/ahs.v22i3.13. Afr Health Sci. 2022. PMID: 36910347 Free PMC article. Clinical Trial.
RESULTS: The mean duration of active phase of labour (hour) was significantly lower in the drotaverine group compared to the control (drotaverine; 6.22 2.41 vs placebo; 8.33 3.56; p <0.001). Also, the cervical dilatation rate (cm/hr) was significantly faster in t …
RESULTS: The mean duration of active phase of labour (hour) was significantly lower in the drotaverine group compared to the control …
Drotaverine Inhibitor of PDE4: Reverses the Streptozotocin Induced Alzheimer's Disease in Mice.
Nazir S, Anwar F, Saleem U, Ahmad B, Raza Z, Sanawar M, Rehman AU, Ismail T. Nazir S, et al. Neurochem Res. 2021 Jul;46(7):1814-1829. doi: 10.1007/s11064-021-03327-9. Epub 2021 Apr 20. Neurochem Res. 2021. PMID: 33877499
The complexity of AD etiology has ever since compelled the researchers to discover multifunctional compounds to combat the AD and neurodegeneration. The aim of this study was to probe into role of drotaverine a PDE4 inhibitor in the management of AD. Albino mice were divid …
The complexity of AD etiology has ever since compelled the researchers to discover multifunctional compounds to combat the AD and neurodegen …
Drotaverine - a Concealed Cytostatic!
Pavel IZ, Heller L, Sommerwerk S, Loesche A, Al-Harrasi A, Csuk R. Pavel IZ, et al. Arch Pharm (Weinheim). 2017 Jan;350(1). doi: 10.1002/ardp.201600289. Epub 2016 Nov 23. Arch Pharm (Weinheim). 2017. PMID: 27879007
Drotaverine (also known as dihydroperparine or No-Spa() ) is an antispasmodic drug closely related to papaverin. ...Extra annexin V-FITC/PI assays and flow cytometry revealed drotaverine mainly to act as a cytostatic and only to a minor extent as cytotoxic agent....
Drotaverine (also known as dihydroperparine or No-Spa() ) is an antispasmodic drug closely related to papaverin. ...Extra annexin V-F
Self-Medication with Drotaverine among Patients with Common Abdominal Symptoms and Treatment Efficacy from the Perspectives of Patients and General Practitioners-An Observational, Retrospective, Cross-Sectional Study Using Real-World Data.
Eder P, Kowalski P, Mastalerz-Migas A, Skrzydlo-Radomanska B, Cichy W, Proga K. Eder P, et al. J Clin Med. 2022 Jun 1;11(11):3156. doi: 10.3390/jcm11113156. J Clin Med. 2022. PMID: 35683543 Free PMC article.
In Poland, drotaverine is the most frequently purchased antispasmodic, yet there is a paucity of real-world data on its use. ...We also asked GPs about the status of drotaverine in their practice. Among 650 recruited patients, 74% used drotaverine for pain, 6 …
In Poland, drotaverine is the most frequently purchased antispasmodic, yet there is a paucity of real-world data on its use. ...We al …
The Influence of Oral Drotaverine Administration on Materno-Fetal Circulation during the Second and Third Trimester of Pregnancy.
Rzymski P, Tomczyk KM, Wilczak M. Rzymski P, et al. Medicina (Kaunas). 2022 Feb 3;58(2):235. doi: 10.3390/medicina58020235. Medicina (Kaunas). 2022. PMID: 35208558 Free PMC article.
Background and Objectives: The study aimed to evaluate the effect of the oral administration of drotaverine on maternal and fetal circulation as measured by Doppler sonography in women with a risk of preterm birth. ...The oral administration of drotaverine has an im …
Background and Objectives: The study aimed to evaluate the effect of the oral administration of drotaverine on maternal and fetal cir …
Drotaverine Hydrochloride Superporous Hydrogel Hybrid System: a Gastroretentive Approach for Sustained Drug Delivery and Enhanced Viscoelasticity.
Farag MM, Louis MM, Badawy AA, Nessem DI, Elmalak NSA. Farag MM, et al. AAPS PharmSciTech. 2022 Apr 26;23(5):124. doi: 10.1208/s12249-022-02280-2. AAPS PharmSciTech. 2022. PMID: 35471680
This study aims to prepare drotaverine hydrochloride superporous hydrogel hybrid systems (DSHH systems) to prolong its residence time in the stomach, provide extended release and reduce its frequency of administration. Drotaverine hydrochloride (DRH) is a spasmolyti …
This study aims to prepare drotaverine hydrochloride superporous hydrogel hybrid systems (DSHH systems) to prolong its residence time …
Compatibility of Drotaverine Hydrochloride with Ibuprofen and Ketoprofen Nonsteroidal Anti-Inflammatory Drugs Mixtures.
Soare AC, Meltzer V, Colbea C, Stanculescu I, Pincu E. Soare AC, et al. Materials (Basel). 2022 Feb 8;15(3):1244. doi: 10.3390/ma15031244. Materials (Basel). 2022. PMID: 35161188 Free PMC article.
Moreover, drug-drug combinations may have a synergistic effect. Drotaverine hydrochloride (D-HCl) is commonly used for its antispasmodic action. ...D-HCl:Ibu and D-HCl:Ket drug-drug interactions leading to the formation of eutectic compositions with increased bioavailabili …
Moreover, drug-drug combinations may have a synergistic effect. Drotaverine hydrochloride (D-HCl) is commonly used for its antispasmo …
Spectrofluorimetric Protocol for Estimation of Commonly Used Antispasmodic Drotaverine. Fluorescence Quenching Study.
Derayea SM, Mahmoud NA, Noureldeen DAM, Attia TZ. Derayea SM, et al. J Fluoresc. 2023 Nov 6. doi: 10.1007/s10895-023-03487-7. Online ahead of print. J Fluoresc. 2023. PMID: 37930598
A fast, simple, accurate, precise, and cheap fluorimetric protocol has been proposed for analysis of a phosphodiesterase-IV inhibitor, namely drotaverine hydrochloride. Fluorimetric protocol is based on estimating the decrease in the eosin Y fluorescence intensity by quant …
A fast, simple, accurate, precise, and cheap fluorimetric protocol has been proposed for analysis of a phosphodiesterase-IV inhibitor, namel …
202 results