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Ebastine.
[No authors listed] [No authors listed] 2021 Sep 20. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2021 Sep 20. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 32352696 Free Books & Documents. Review.
Ebastine is a nonsedating antihistamine that is not available in the United States, but is available in other countries. ...
Ebastine is a nonsedating antihistamine that is not available in the United States, but is available in other countries. ...
Ebastine in the Treatment of Allergic Rhinitis and Urticaria: 30 Years of Clinical Studies and Real-World Experience.
Sastre J. Sastre J. J Investig Allergol Clin Immunol. 2020;30(3):156-168. doi: 10.18176/jiaci.0401. Epub 2019 Apr 12. J Investig Allergol Clin Immunol. 2020. PMID: 30977465 Free article. Review.
H1-antihistamines, which stabilize the receptor in its inactive form, are the treatment of choice for some chronic allergic conditions. Ebastine is a well-established secondgeneration oral H1-antihistamine that is administered once daily at a dose of 10-20 mg and is availa …
H1-antihistamines, which stabilize the receptor in its inactive form, are the treatment of choice for some chronic allergic conditions. E …
Ebastine in allergic rhinitis and chronic idiopathic urticaria.
Sastre J. Sastre J. Allergy. 2008 Dec;63 Suppl 89:1-20. doi: 10.1111/j.1398-9995.2008.01897.x. Allergy. 2008. PMID: 19032340 Review.
In addition, ebastine was significantly more effective than placebo at relieving the symptoms of chronic idiopathic urticaria. ...In conclusion, ebastine is an effective and generally well-tolerated treatment for allergic rhinitis and chronic idiopathic urticaria. . …
In addition, ebastine was significantly more effective than placebo at relieving the symptoms of chronic idiopathic urticaria. ...In …
Ebastine in context. Introduction.
Buendia E. Buendia E. Drugs. 1996;52 Suppl 1:1-7. doi: 10.2165/00003495-199600521-00003. Drugs. 1996. PMID: 8828020 Review.
Second generation antihistamines are free of the sedative and anticholinergic effects characteristic of the first generation agents. Ebastine, the focus of this supplement, is a new second generation agent that has shown antihistamine activity in preclinical studies and cl …
Second generation antihistamines are free of the sedative and anticholinergic effects characteristic of the first generation agents. Ebas …
Ebastine: an update of its use in allergic disorders.
Hurst M, Spencer CM. Hurst M, et al. Drugs. 2000 Apr;59(4):981-1006. doi: 10.2165/00003495-200059040-00018. Drugs. 2000. PMID: 10804044 Review.
Ebastine is a second-generation antihistamine which undergoes transformation to its active metabolite, carebastine. ...Ebastine does not appear to be associated with any significant cardiac adverse events. ...
Ebastine is a second-generation antihistamine which undergoes transformation to its active metabolite, carebastine. ...Ebastine …
Ebastine. a review of its pharmacological properties and clinical efficacy in the treatment of allergic disorders.
Wiseman LR, Faulds D. Wiseman LR, et al. Drugs. 1996 Feb;51(2):260-77. doi: 10.2165/00003495-199651020-00006. Drugs. 1996. PMID: 8808167 Review.
Ebastine is a long-acting nonsedating second generation histamine H1 receptor antagonist which binds preferentially to peripheral H1 receptors in vivo. ...Serious adverse cardiac events, observed on rare occasions with some other histamine H1 receptor antagonists, have not …
Ebastine is a long-acting nonsedating second generation histamine H1 receptor antagonist which binds preferentially to peripheral H1 …
Ebastine impairs metastatic spread in triple-negative breast cancer by targeting focal adhesion kinase.
Seo J, Park M, Ko D, Kim S, Park JM, Park S, Nam KD, Farrand L, Yang J, Seok C, Jung E, Kim YJ, Kim JY, Seo JH. Seo J, et al. Cell Mol Life Sci. 2023 Apr 25;80(5):132. doi: 10.1007/s00018-023-04760-5. Cell Mol Life Sci. 2023. PMID: 37185776 Free PMC article.
We sought to investigate the utility of ebastine (EBA), a second-generation antihistamine with potent anti-metastatic properties, in the context of breast cancer stem cell (BCSC)-suppression in triple-negative breast cancer (TNBC). ...
We sought to investigate the utility of ebastine (EBA), a second-generation antihistamine with potent anti-metastatic properties, in …
Cardiac effects of ebastine and other antihistamines in humans.
Moss AJ, Morganroth J. Moss AJ, et al. Drug Saf. 1999;21 Suppl 1:69-80; discussion 81-7. doi: 10.2165/00002018-199921001-00009. Drug Saf. 1999. PMID: 10597870 Review.
Interaction studies involving ebastine with ketoconazole revealed a significant increase in the serum ebastine concentration and in the elimination half-life of ebastine, with a modest 18.1 msec increase in QTc (approximately 10 msec above ketoconazole alone) …
Interaction studies involving ebastine with ketoconazole revealed a significant increase in the serum ebastine concentration a …
Repositioning the antihistamine ebastine as an intracellular siRNA delivery enhancer.
Muntean C, Blondeel E, Harinck L, Pednekar K, Prakash J, De Wever O, Chain JL, De Smedt SC, Remaut K, Raemdonck K. Muntean C, et al. Int J Pharm. 2023 Sep 25;644:123348. doi: 10.1016/j.ijpharm.2023.123348. Epub 2023 Aug 24. Int J Pharm. 2023. PMID: 37633539
In particular, we demonstrated that ebastine can improve the siRNA-mediated gene silencing efficiency of a polymeric nanogel by 40-fold, outperforming other CAD compounds. ...Altogether, we identified ebastine as a potent and versatile siRNA delivery enhancer in can …
In particular, we demonstrated that ebastine can improve the siRNA-mediated gene silencing efficiency of a polymeric nanogel by 40-fo …
A Critical Review of Physicochemical Properties and Analytical Methods Applied to Quantitative Determination of Ebastine.
Frare RG, Singh AK. Frare RG, et al. Crit Rev Anal Chem. 2018 Mar 4;48(2):102-109. doi: 10.1080/10408347.2017.1412816. Epub 2018 Jan 23. Crit Rev Anal Chem. 2018. PMID: 29235880 Review.
To ensure the quality, efficacy, safety, and effectiveness of ebastine drug products, efficient and reliable analytical methods are mandatory. ...In this work, we present a critical review on characteristics, physicochemical properties, and analytical methods applied in th …
To ensure the quality, efficacy, safety, and effectiveness of ebastine drug products, efficient and reliable analytical methods are m …
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