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EGCG-based nanoparticles: synthesis, properties, and applications.
Peng X, McClements DJ, Liu X, Liu F. Peng X, et al. Crit Rev Food Sci Nutr. 2024 Mar 22:1-22. doi: 10.1080/10408398.2024.2328184. Online ahead of print. Crit Rev Food Sci Nutr. 2024. PMID: 38520117 Review.
The potential application of nanoencapsulated EGCG in functional foods and beverages is also emphasized. Top-down and bottom-up approaches can be used to construct EGCG-based nanoparticles. EGCG-based nanoparticles exhibit enhanced stability and bioavailabili …
The potential application of nanoencapsulated EGCG in functional foods and beverages is also emphasized. Top-down and bottom-up appro …
Green tea derivative (-)-epigallocatechin-3-gallate (EGCG) confers protection against ionizing radiation-induced intestinal epithelial cell death both in vitro and in vivo.
Xie LW, Cai S, Zhao TS, Li M, Tian Y. Xie LW, et al. Free Radic Biol Med. 2020 Dec;161:175-186. doi: 10.1016/j.freeradbiomed.2020.10.012. Epub 2020 Oct 15. Free Radic Biol Med. 2020. PMID: 33069855 Free article.
The therapeutic effects and mechanism of EGCG on RIII have not yet been determined. In the present study, we investigated whether EGCG confers radioprotection against RIII. ...Treatment with the Nrf2 inhibitor ML385 abolished the protective effects of EGCG, i …
The therapeutic effects and mechanism of EGCG on RIII have not yet been determined. In the present study, we investigated whether …
The Epigenetic Modification of Epigallocatechin Gallate (EGCG) on Cancer.
Yang L, Zhang W, Chopra S, Kaur D, Wang H, Li M, Chen P, Zhang W. Yang L, et al. Curr Drug Targets. 2020;21(11):1099-1104. doi: 10.2174/1389450121666200504080112. Curr Drug Targets. 2020. PMID: 32364072 Review.
Among the major components of green tea, epigallocatechin-3-gallate (EGCG) is the most effective for its anti-cancer characteristics. ...Recently, several proteins have been identified as miRNA direct interactors by EGCG. However, the mechanisms explaining the actio …
Among the major components of green tea, epigallocatechin-3-gallate (EGCG) is the most effective for its anti-cancer characteristics. …
Gut microbiota from green tea polyphenol-dosed mice improves intestinal epithelial homeostasis and ameliorates experimental colitis.
Wu Z, Huang S, Li T, Li N, Han D, Zhang B, Xu ZZ, Zhang S, Pang J, Wang S, Zhang G, Zhao J, Wang J. Wu Z, et al. Microbiome. 2021 Sep 7;9(1):184. doi: 10.1186/s40168-021-01115-9. Microbiome. 2021. PMID: 34493333 Free PMC article.
Next, we demonstrated that the EGCG pre-supplementation induced similar beneficial outcomes to oral EGCG administration. ...Our findings provide novel insights into EGCG-mediated remission of IBD and EGCG as a potential modulator for gut microbiota to …
Next, we demonstrated that the EGCG pre-supplementation induced similar beneficial outcomes to oral EGCG administration. ...Ou …
Green Tea Suppresses Brain Aging.
Unno K, Nakamura Y. Unno K, et al. Molecules. 2021 Aug 12;26(16):4897. doi: 10.3390/molecules26164897. Molecules. 2021. PMID: 34443485 Free PMC article. Review.
The most important component of green tea is epigallocatechin gallate (EGCG). Both EGCG and epigallocatechin (EGC) have been suggested to cross the blood-brain barrier to reach the brain parenchyma, but EGCG has been found to be more effective than EGC in pro …
The most important component of green tea is epigallocatechin gallate (EGCG). Both EGCG and epigallocatechin (EGC) have been s …
Therapeutic effects of EGCG: a patent review.
Chakrawarti L, Agrawal R, Dang S, Gupta S, Gabrani R. Chakrawarti L, et al. Expert Opin Ther Pat. 2016 Aug;26(8):907-16. doi: 10.1080/13543776.2016.1203419. Epub 2016 Jun 29. Expert Opin Ther Pat. 2016. PMID: 27338088 Review.
Recent advances, which include the use of nanoencapsulated EGCG to enhance the drug delivery and reduce cell toxicity, have also been discussed along with the comprehensive analysis of the specific granted patents associated with EGCG. EXPERT OPINION: Under the curr …
Recent advances, which include the use of nanoencapsulated EGCG to enhance the drug delivery and reduce cell toxicity, have also been …
Potential protective mechanisms of green tea polyphenol EGCG against COVID-19.
Zhang Z, Zhang X, Bi K, He Y, Yan W, Yang CS, Zhang J. Zhang Z, et al. Trends Food Sci Technol. 2021 Aug;114:11-24. doi: 10.1016/j.tifs.2021.05.023. Epub 2021 May 25. Trends Food Sci Technol. 2021. PMID: 34054222 Free PMC article. Review.
KEY FINDINGS AND CONCLUSIONS: EGCG, via activating Nrf2, can suppress ACE2 (a cellular receptor for SARS-CoV-2) and TMPRSS2, which mediate cell entry of the virus. Through inhibition of SARS-CoV-2 main protease, EGCG may inhibit viral reproduction. EGCG via i …
KEY FINDINGS AND CONCLUSIONS: EGCG, via activating Nrf2, can suppress ACE2 (a cellular receptor for SARS-CoV-2) and TMPRSS2, which me …
Mechanisms Underlying the Effects of the Green Tea Polyphenol EGCG in Sarcopenia Prevention and Management.
Wang T, Xu H, Wu S, Guo Y, Zhao G, Wang D. Wang T, et al. J Agric Food Chem. 2023 Jun 28;71(25):9609-9627. doi: 10.1021/acs.jafc.3c02023. Epub 2023 Jun 14. J Agric Food Chem. 2023. PMID: 37316469 Review.
In this comprehensive review, we discuss the potential role and underlying mechanisms of EGCG in sarcopenia prevention and management. We thoroughly review the general biological activities and general effects of EGCG on skeletal muscle performance, EGCG's an …
In this comprehensive review, we discuss the potential role and underlying mechanisms of EGCG in sarcopenia prevention and management …
The Intrinsic Virtues of EGCG, an Extremely Good Cell Guardian, on Prevention and Treatment of Diabesity Complications.
Potenza MA, Iacobazzi D, Sgarra L, Montagnani M. Potenza MA, et al. Molecules. 2020 Jul 4;25(13):3061. doi: 10.3390/molecules25133061. Molecules. 2020. PMID: 32635492 Free PMC article. Review.
Biologic actions of EGCG are concentration-dependent and under certain conditions EGCG may exert pro-oxidant activities, including generation of free radicals. The discovery of 67-kDa laminin as potential EGCG membrane target has broaden the likelihood that …
Biologic actions of EGCG are concentration-dependent and under certain conditions EGCG may exert pro-oxidant activities, inclu …
L-EGCG-Mn nanoparticles as a pH-sensitive MRI contrast agent.
Li J, Jiang X, Shang L, Li Z, Yang C, Luo Y, Hu D, Shen Y, Zhang Z. Li J, et al. Drug Deliv. 2021 Dec;28(1):134-143. doi: 10.1080/10717544.2020.1862363. Drug Deliv. 2021. PMID: 33356629 Free PMC article.
Reverse microemulsion was used to obtain the L-EGCG-Mn NPs. The physicochemical properties of L-EGCG-Mn were characterized using dynamic light scattering, transmission electron microscopy, and near-infrared fluorescence small animal live imaging. ...Cytotoxicity tes …
Reverse microemulsion was used to obtain the L-EGCG-Mn NPs. The physicochemical properties of L-EGCG-Mn were characterized usi …
7,371 results