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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1843 1
1870 1
1872 1
1875 1
1878 1
1923 1
1926 1
1940 1
1946 1
1947 4
1948 1
1949 1
1950 4
1951 2
1952 6
1953 4
1954 5
1955 4
1956 7
1957 9
1958 2
1959 2
1960 2
1961 2
1962 3
1963 5
1964 11
1965 10
1966 11
1967 3
1968 6
1969 6
1970 6
1971 9
1972 13
1973 14
1974 15
1975 64
1976 60
1977 59
1978 53
1979 46
1980 56
1981 56
1982 67
1983 73
1984 88
1985 83
1986 77
1987 69
1988 58
1989 54
1990 66
1991 58
1992 42
1993 49
1994 43
1995 48
1996 35
1997 39
1998 24
1999 45
2000 37
2001 40
2002 38
2003 44
2004 33
2005 45
2006 45
2007 32
2008 27
2009 37
2010 28
2011 23
2012 27
2013 30
2014 23
2015 19
2016 25
2017 23
2018 21
2019 13
2020 23
2021 17
2022 15
2023 19
2024 8

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2,197 results

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Page 1
Midazolam as an anti-emetic.
Rodolà F. Rodolà F. Eur Rev Med Pharmacol Sci. 2006 May-Jun;10(3):121-6. Eur Rev Med Pharmacol Sci. 2006. PMID: 16875045 Review.
Midazolam, a short acting benzodiazepine widely used as a premedicant before surgery, for induction of anaesthesia, and for conscious sedation, has been particularly studied, sometimes with conflicting results. This paper will discuss the possible mechanisms of action of m …
Midazolam, a short acting benzodiazepine widely used as a premedicant before surgery, for induction of anaesthesia, and for conscious sedati …
Cannaboinoid Antiemetic Therapy.
Taylor BN, Mueller M, Sauls RS. Taylor BN, et al. 2023 Aug 14. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Aug 14. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 30571051 Free Books & Documents.
Dronabinol and nabilone are both synthetic tetrahydrocannabinol (THC) which the FDA has approved for the treatment of chemotherapy-induced nausea and vomiting (CINV) after the failure of a trial of first-line anti-emetics. Both are also FDA-approved to treat anorexia assoc …
Dronabinol and nabilone are both synthetic tetrahydrocannabinol (THC) which the FDA has approved for the treatment of chemotherapy-induced n …
Advances in anti-emetic therapy.
Bakowski MT. Bakowski MT. Cancer Treat Rev. 1984 Sep;11(3):237-56. doi: 10.1016/0305-7372(84)90010-0. Cancer Treat Rev. 1984. PMID: 6098368 Review.
The degree of control of emesis relates both to the intensity of the emetogenic stimulus and to the effectiveness of the anti-emetic agent employed. Prochlorperazine is a relatively weak anti-emetic. ...Dexamethasone activity as a single agent is in doubt but the dr …
The degree of control of emesis relates both to the intensity of the emetogenic stimulus and to the effectiveness of the anti-emetic
Herbal antitussives.
Ziment I. Ziment I. Pulm Pharmacol Ther. 2002;15(3):327-33. doi: 10.1006/pupt.2002.0343. Pulm Pharmacol Ther. 2002. PMID: 12099787 Review.
The mechanisms of actions of cough medicines are not always known. The problem is exacerbated for herbal medicines, where the effectiveness of the plant or its phytochemicals have rarely been carefully evaluated. ...Most popular herbs used as cough medicines appear to be d …
The mechanisms of actions of cough medicines are not always known. The problem is exacerbated for herbal medicines, where the effecti …
Anti-emetic therapy in cancer chemotherapy: current status.
Herrstedt J, Dombernowsky P. Herrstedt J, et al. Basic Clin Pharmacol Toxicol. 2007 Sep;101(3):143-50. doi: 10.1111/j.1742-7843.2007.00122.x. Basic Clin Pharmacol Toxicol. 2007. PMID: 17697032 Free article. Review.
The drugs used included dopamine(2)-receptor antagonists and corticosteroids alone or combined. This review summarizes the development of anti-emetic therapy, but will focus on the importance of two new classes of anti-emetics: the serotonin(3)- and the neurokinin(1 …
The drugs used included dopamine(2)-receptor antagonists and corticosteroids alone or combined. This review summarizes the development of an …
Adopting the Rumsfeld approach to understanding the action of levodopa and apomorphine in Parkinson's disease.
Jenner P, Falup-Pecurariu C, Leta V, Verin M, Auffret M, Bhidayasiri R, Weiss D, Borovečki F, Jost WH. Jenner P, et al. J Neural Transm (Vienna). 2023 Nov;130(11):1337-1347. doi: 10.1007/s00702-023-02655-0. Epub 2023 May 20. J Neural Transm (Vienna). 2023. PMID: 37210460 Free PMC article. Review.
Two of the oldest drugs used appear more effective than others-levodopa and apomorphine-but the reasons for this are seldom discussed and this may be one cause for a lack of progress. This short review questions current thinking on drug action and looks at whether adopting …
Two of the oldest drugs used appear more effective than others-levodopa and apomorphine-but the reasons for this are seldom discussed and th …
[Cardiotoxicity of emetine].
Marino A, Costa R, De Natale G. Marino A, et al. Clin Ter. 1990 May 15;133(3):131-43. Clin Ter. 1990. PMID: 2142900 Review. Italian.
The authors review the hypotheses that have been suggested concerning the mechanism of this cardiotoxic action....
The authors review the hypotheses that have been suggested concerning the mechanism of this cardiotoxic action....
Role of apomorphine in the treatment of Parkinson's disease.
Boyle A, Ondo W. Boyle A, et al. CNS Drugs. 2015 Feb;29(2):83-9. doi: 10.1007/s40263-014-0221-z. CNS Drugs. 2015. PMID: 25676564 Review.
The highly lipophilic structure allows apomorphine to cross cell membranes rapidly, leading to the rapid onset of action for on/off symptoms of PD. The use of apomorphine was limited in the past due to peripheral side effects, but with the advent of better delivery systems …
The highly lipophilic structure allows apomorphine to cross cell membranes rapidly, leading to the rapid onset of action for on/off s …
A History of Drug Discovery for Treatment of Nausea and Vomiting and the Implications for Future Research.
Sanger GJ, Andrews PLR. Sanger GJ, et al. Front Pharmacol. 2018 Sep 4;9:913. doi: 10.3389/fphar.2018.00913. eCollection 2018. Front Pharmacol. 2018. PMID: 30233361 Free PMC article. Review.
The origins of the major classes of current anti-emetics are examined. Serendipity is a recurrent theme in discovery of their anti-emetic properties and repurposing from one indication to another is a continuing trend. ...Pre-clinical studies showed that anti-eme
The origins of the major classes of current anti-emetics are examined. Serendipity is a recurrent theme in discovery of their anti- …
Apomorphine hydrochloride for the treatment of Parkinson's disease.
Unti E, Ceravolo R, Bonuccelli U. Unti E, et al. Expert Rev Neurother. 2015;15(7):723-32. doi: 10.1586/14737175.2015.1051468. Epub 2015 Jun 2. Expert Rev Neurother. 2015. PMID: 26037961 Review.
Bioavailability is close to 100%. It has a rapid antiparkinsonian action after subcutaneous (s.c.) administration with a size effect comparable with that of levodopa. ...
Bioavailability is close to 100%. It has a rapid antiparkinsonian action after subcutaneous (s.c.) administration with a size effect …
2,197 results