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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 1
1946 5
1947 4
1948 6
1949 4
1950 9
1951 3
1952 15
1953 14
1954 12
1955 14
1956 11
1957 8
1958 6
1959 13
1960 10
1961 11
1962 14
1963 28
1964 56
1965 37
1966 31
1967 55
1968 71
1969 72
1970 87
1971 83
1972 87
1973 137
1974 136
1975 128
1976 116
1977 114
1978 145
1979 145
1980 149
1981 135
1982 169
1983 146
1984 170
1985 212
1986 196
1987 188
1988 161
1989 265
1990 235
1991 274
1992 243
1993 326
1994 340
1995 339
1996 380
1997 386
1998 430
1999 500
2000 609
2001 637
2002 588
2003 805
2004 911
2005 1051
2006 1155
2007 1333
2008 1470
2009 1507
2010 1605
2011 1706
2012 2062
2013 2244
2014 2246
2015 2420
2016 2489
2017 2610
2018 2855
2019 2964
2020 3338
2021 3445
2022 3394
2023 3369
2024 1334

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47,873 results

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Page 1
Brain circuits for pain and its treatment.
Mercer Lindsay N, Chen C, Gilam G, Mackey S, Scherrer G. Mercer Lindsay N, et al. Sci Transl Med. 2021 Nov 10;13(619):eabj7360. doi: 10.1126/scitranslmed.abj7360. Epub 2021 Nov 10. Sci Transl Med. 2021. PMID: 34757810 Free PMC article. Review.
Pain aversiveness is one principal cause of suffering for patients with chronic pain, motivating research and drug development efforts to investigate and modulate neural activity in the brain's circuits encoding pain unpleasantness. Here, we review progress i …
Pain aversiveness is one principal cause of suffering for patients with chronic pain, motivating research and drug development …
Cognitive and emotional control of pain and its disruption in chronic pain.
Bushnell MC, Ceko M, Low LA. Bushnell MC, et al. Nat Rev Neurosci. 2013 Jul;14(7):502-11. doi: 10.1038/nrn3516. Epub 2013 May 30. Nat Rev Neurosci. 2013. PMID: 23719569 Free PMC article. Review.
This article will review the neural mechanisms underlying the modulation of pain by cognitive and emotional states - important components of mind-body therapies. It will also examine the accumulating evidence that chronic pain itself alters brain circuitry, i …
This article will review the neural mechanisms underlying the modulation of pain by cognitive and emotional states - important …
Brain changes associated with cognitive and emotional factors in chronic pain: A systematic review.
Malfliet A, Coppieters I, Van Wilgen P, Kregel J, De Pauw R, Dolphens M, Ickmans K. Malfliet A, et al. Eur J Pain. 2017 May;21(5):769-786. doi: 10.1002/ejp.1003. Epub 2017 Feb 1. Eur J Pain. 2017. PMID: 28146315 Free article. Review.
Evidence on the direction of these associations is inconclusive. Pain catastrophizing is related to brain areas involved in pain processing, attention to pain, emotion and motor activity, and to reduced top-down pain inhibition. ...SIGNIFICANCE: …
Evidence on the direction of these associations is inconclusive. Pain catastrophizing is related to brain areas involved in pain …
Emotional and Cognitive Influences on Pain Experience.
Peters ML. Peters ML. Mod Trends Pharmacopsychiatry. 2015;30:138-52. doi: 10.1159/000435938. Epub 2015 Sep 18. Mod Trends Pharmacopsychiatry. 2015. PMID: 26436897 Review.
Multiple emotional and cognitive factors impact on the experience of pain. This chapter will review some of the most important emotional and cognitive determinants of the pain experience as found in experimental and clinical studies with human particip …
Multiple emotional and cognitive factors impact on the experience of pain. This chapter will review some of the most important …
Pain and emotion: a biopsychosocial review of recent research.
Lumley MA, Cohen JL, Borszcz GS, Cano A, Radcliffe AM, Porter LS, Schubiner H, Keefe FJ. Lumley MA, et al. J Clin Psychol. 2011 Sep;67(9):942-68. doi: 10.1002/jclp.20816. Epub 2011 Jun 6. J Clin Psychol. 2011. PMID: 21647882 Free PMC article. Review.
OBJECTIVE AND METHOD: Research on emotion and pain has burgeoned. We review the last decade's literature, focusing on links between emotional processes and persistent pain. ...Psychological research demonstrates that greater pain is related to …
OBJECTIVE AND METHOD: Research on emotion and pain has burgeoned. We review the last decade's literature, focusing on links be …
Positive emotions and brain reward circuits in chronic pain.
Navratilova E, Morimura K, Xie JY, Atcherley CW, Ossipov MH, Porreca F. Navratilova E, et al. J Comp Neurol. 2016 Jun 1;524(8):1646-52. doi: 10.1002/cne.23968. Epub 2016 Feb 3. J Comp Neurol. 2016. PMID: 26788716 Free PMC article. Review.
Chronic pain is often accompanied by comorbid emotional disorders including anxiety, depression, and possibly anhedonia. ...Adaptations in brain reward circuits may be fundamental to the pathology of chronic pain. Knowledge of brain reward processing in the c …
Chronic pain is often accompanied by comorbid emotional disorders including anxiety, depression, and possibly anhedonia. ...Ad …
The cerebral signature for pain perception and its modulation.
Tracey I, Mantyh PW. Tracey I, et al. Neuron. 2007 Aug 2;55(3):377-91. doi: 10.1016/j.neuron.2007.07.012. Neuron. 2007. PMID: 17678852 Free article. Review.
Relating neural activity changes to the varied pain experiences has led to an increased awareness of how factors (e.g., cognition, emotion, context, injury) can separately influence pain perception. Tying this body of knowledge in humans to work in animal mod …
Relating neural activity changes to the varied pain experiences has led to an increased awareness of how factors (e.g., cognition, …
Pain-related negative emotions and placebo analgesia.
Flaten MA. Flaten MA. Handb Exp Pharmacol. 2014;225:81-96. doi: 10.1007/978-3-662-44519-8_5. Handb Exp Pharmacol. 2014. PMID: 25304527 Review.
Individuals undergoing treatment for a symptom like pain expect that the treatment will reduce the pain. Many studies show that healthy volunteers or patients in pain report less pain after inactive treatment, if they believe that active medication has …
Individuals undergoing treatment for a symptom like pain expect that the treatment will reduce the pain. Many studies show tha …
Music and the heart.
Koelsch S, Jäncke L. Koelsch S, et al. Eur Heart J. 2015 Nov 21;36(44):3043-9. doi: 10.1093/eurheartj/ehv430. Epub 2015 Sep 9. Eur Heart J. 2015. PMID: 26354957 Free article. Review.
Music can powerfully evoke and modulate emotions and moods, along with changes in heart activity, blood pressure (BP), and breathing. ...In patients with heart disease (similar to other patient groups), music can reduce pain and anxiety, associated with lower HR and …
Music can powerfully evoke and modulate emotions and moods, along with changes in heart activity, blood pressure (BP), and breathing. …
Pain: Is It All in the Brain or the Heart?
Alshami AM. Alshami AM. Curr Pain Headache Rep. 2019 Nov 14;23(12):88. doi: 10.1007/s11916-019-0827-4. Curr Pain Headache Rep. 2019. PMID: 31728781 Review.
Pain is not only a sensory experience, but also can be associated with emotional, cognitive, and social components. ...It has its neural network or "little brain." The methods targeting the heart modulate pain regions in the brain. These methods seem to modul …
Pain is not only a sensory experience, but also can be associated with emotional, cognitive, and social components. ...It has …
47,873 results
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