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Properties of scyllo-inositol as a therapeutic treatment of AD-like pathology.
Fenili D, Brown M, Rappaport R, McLaurin J. Fenili D, et al. J Mol Med (Berl). 2007 Jun;85(6):603-11. doi: 10.1007/s00109-007-0156-7. Epub 2007 Feb 6. J Mol Med (Berl). 2007. PMID: 17279347
Inositol is a simple polyol with eight naturally occurring stereoisomers. myo-Inositol, D-chiro- and epi-inositol have been examined as potential therapeutic agents for various diseases, with favorable results, but treatment with scyllo-inositol has not been previou …
Inositol is a simple polyol with eight naturally occurring stereoisomers. myo-Inositol, D-chiro- and epi-inositol have been ex …
General amyloid inhibitors? A critical examination of the inhibition of IAPP amyloid formation by inositol stereoisomers.
Wang H, Raleigh DP. Wang H, et al. PLoS One. 2014 Sep 26;9(9):e104023. doi: 10.1371/journal.pone.0104023. eCollection 2014. PLoS One. 2014. PMID: 25260075 Free PMC article.
IAPP and Abeta, the peptide responsible for amyloid formation in Alzheimer's disease, are particularly interesting in this regard as they are both natively unfolded in their monomeric states and share some common characteristics. ...A range of compounds inhib …
IAPP and Abeta, the peptide responsible for amyloid formation in Alzheimer's disease, are particularly interesting in t …