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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1987 1
1990 1
1999 2
2002 1
2003 1
2004 5
2005 1
2006 2
2007 3
2008 2
2009 4
2010 1
2011 1
2013 1
2014 3
2016 2
2017 2
2024 0

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29 results

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Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Epinastine 0.05% ophthalmic solution in contact lens-wearing subjects with a history of allergic conjunctivitis.
Nichols KK, Morris S, Gaddie IB, Evans D. Nichols KK, et al. Eye Contact Lens. 2009 Jan;35(1):26-31. doi: 10.1097/ICL.0b013e318193a3df. Eye Contact Lens. 2009. PMID: 19125045 Clinical Trial.
Epinastine provided significantly greater improvements from baseline in ocular itch and overall eye comfort compared with rewetting drops alone (P<or=0.001). CONCLUSIONS: Epinastine 0.05% may be useful for the treatment of seasonal allergic conjunctivitis in cont
Epinastine provided significantly greater improvements from baseline in ocular itch and overall eye comfort compared with rewetting d
Efficacy of epinastine hydrochloride ophthalmic solution in allergic conjunctivitis by conjunctival cedar pollen allergen challenge.
Fujishima H, Ohashi Y, Takamura E. Fujishima H, et al. Ann Allergy Asthma Immunol. 2014 Oct;113(4):476-81. doi: 10.1016/j.anai.2014.07.007. Epub 2014 Aug 20. Ann Allergy Asthma Immunol. 2014. PMID: 25163405 Clinical Trial.
In addition, epinastine demonstrated noninferiority to olopatadine for ocular itching and conjunctival hyperemia. No adverse drug reactions or serious adverse events were reported throughout the study, indicating that epinastine has a good safety profile. CONCLUSION …
In addition, epinastine demonstrated noninferiority to olopatadine for ocular itching and conjunctival hyperemia. No adverse drug rea …
Clinical efficacy of olopatadine vs epinastine ophthalmic solution in the conjunctival allergen challenge model.
Lanier BQ, Finegold I, D'Arienzo P, Granet D, Epstein AB, Ledgerwood GL. Lanier BQ, et al. Curr Med Res Opin. 2004 Aug;20(8):1227-33. doi: 10.1185/030079904125004330. Curr Med Res Opin. 2004. PMID: 15324525 Clinical Trial.
BACKGROUND: Olopatadine hydrochloride 0.1% ophthalmic solution (Patanol) and epinastine hydrochloride 0.05% ophthalmic solution (Elestat) are two topical antiallergic agents. ...MAIN OUTCOME MEASURES; RESULTS: Fifty-three subjects were randomized into the olopatadine/ep
BACKGROUND: Olopatadine hydrochloride 0.1% ophthalmic solution (Patanol) and epinastine hydrochloride 0.05% ophthalmic solution (Eles …
Antitussive effects of the H1-receptor antagonist epinastine in patients with atopic cough (eosinophilic bronchitis).
Shioya T, Satake M, Kagaya M, Sano MA, Watanabe A, Fukui S, Sasaki M. Shioya T, et al. Arzneimittelforschung. 2004;54(4):207-12. doi: 10.1055/s-0031-1296961. Arzneimittelforschung. 2004. PMID: 15146933 Clinical Trial.
To investigate the antitussive effects of a histamine H1-recetor antagonist, epinastine hydrochloride (epinastine, CAS 80012-43-7, Alesion; 20 mg/day, once daily), cough scores, pulmonary function, capsaicin cough threshold, and bronchial hyperresonsiveness (BHR) to …
To investigate the antitussive effects of a histamine H1-recetor antagonist, epinastine hydrochloride (epinastine, CAS 80012-4 …
Efficacy and tolerability of ophthalmic epinastine assessed using the conjunctival antigen challenge model in patients with a history of allergic conjunctivitis.
Abelson MB, Gomes P, Crampton HJ, Schiffman RM, Bradford RR, Whitcup SM. Abelson MB, et al. Clin Ther. 2004 Jan;26(1):35-47. doi: 10.1016/s0149-2918(04)90004-5. Clin Ther. 2004. PMID: 14996516 Clinical Trial.
CONCLUSIONS: In this CAC model, multiple signs and symptoms of allergic conjunctivitis were significantly reduced by instillation of epinastine compared with vehicle. Epinastine showed prompt onset (3 minutes) and long duration of action (>or=8 hours). The tolera …
CONCLUSIONS: In this CAC model, multiple signs and symptoms of allergic conjunctivitis were significantly reduced by instillation of epin
Efficacy and tolerability of ophthalmic epinastine: a randomized, double-masked, parallel-group, active- and vehicle-controlled environmental trial in patients with seasonal allergic conjunctivitis.
Whitcup SM, Bradford R, Lue J, Schiffman RM, Abelson MB. Whitcup SM, et al. Clin Ther. 2004 Jan;26(1):29-34. doi: 10.1016/s0149-2918(04)90003-3. Clin Ther. 2004. PMID: 14996515 Clinical Trial.
BACKGROUND: Epinastine hydrochloride is an antihistamine with mast cell-stabilizing and anti-inflammatory activity. ...Epinastine was well tolerated....
BACKGROUND: Epinastine hydrochloride is an antihistamine with mast cell-stabilizing and anti-inflammatory activity. ...Epinastine
Antihistaminic activity and side effect profile of epinastine and terfenadine in healthy volunteers.
Schilling JC, Adamus WS, Kuthan H. Schilling JC, et al. Int J Clin Pharmacol Ther Toxicol. 1990 Dec;28(12):493-7. Int J Clin Pharmacol Ther Toxicol. 1990. PMID: 1982280 Clinical Trial.
In addition, all epinastine dosages had a distinctly faster onset of action than terfenadine. ...The psychometric tests for CNS effects did not reveal any difference among epinastine, terfenadine and placebo. In conclusion, epinastine is one of the most effec …
In addition, all epinastine dosages had a distinctly faster onset of action than terfenadine. ...The psychometric tests for CNS effec …
Efficacy and comfort of olopatadine 0.2% versus epinastine 0.05% ophthalmic solution for treating itching and redness induced by conjunctival allergen challenge.
Mah FS, Rosenwasser LJ, Townsend WD, Greiner JV, Bensch G. Mah FS, et al. Curr Med Res Opin. 2007 Jun;23(6):1445-52. doi: 10.1185/030079907X188206. Epub 2007 May 18. Curr Med Res Opin. 2007. PMID: 17559743 Clinical Trial.
At Visit 3, 92 subjects were randomized into one of four treatment groups to receive one drop of study medication in each eye: (1) olopatadine 0.2%/placebo, (2) epinastine 0.05%/placebo, (3) olopatadine 0.2%/epinastine 0.05%, (4) placebo/placebo. ...Olopatadine 0.2% …
At Visit 3, 92 subjects were randomized into one of four treatment groups to receive one drop of study medication in each eye: (1) olopatadi …
Efficacy and response with olopatadine versus epinastine in ocular allergic symptoms: a post hoc analysis of data from a conjunctival allergen challenge study.
Finegold I, Granet DB, D'Arienzo PA, Epstein AB. Finegold I, et al. Clin Ther. 2006 Oct;28(10):1630-8. doi: 10.1016/j.clinthera.2006.10.003. Clin Ther. 2006. PMID: 17157118 Clinical Trial.
Adult patients with allergic conjunctivitis were screened (visits 1 and 2); those who exhibited positive allergic reactions at both visits were randomized to 1 of 3 groups. olopatadine/epinastine, olopatadine/placebo, or epinastine/placebo. At visit 3, each eye was …
Adult patients with allergic conjunctivitis were screened (visits 1 and 2); those who exhibited positive allergic reactions at both visits w …
Dermal objective pharmacodynamic profile of cetirizine and epinastine: two controlled, randomised, double-blind, crossover studies.
Leroy T, van Neste D. Leroy T, et al. Int J Clin Pract. 2002 Oct;56(8):568-73. Int J Clin Pract. 2002. PMID: 12425364 Clinical Trial.
With the notable exception of 1 hr post dose wheal values, which were consistently smaller after epinastine, cetirizine was superior to epinastine for both wheal and flare at all other times. ...At all other time points, cetirizine was generally more effective than …
With the notable exception of 1 hr post dose wheal values, which were consistently smaller after epinastine, cetirizine was superior …
29 results