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Showing results for spedifen
Your search for espidifen retrieved no results
Clinical pharmacokinetics of ibuprofen arginine.
Cattaneo D, Clementi E. Cattaneo D, et al. Curr Clin Pharmacol. 2010 Nov;5(4):239-45. doi: 10.2174/157488410793352012. Curr Clin Pharmacol. 2010. PMID: 20925647 Review.
This review will mainly deal with the clinical pharmacokinetics of ibuprofen arginine, an alternative formulation specifically designed to improve the absorption of ibuprofen. ...Taken together, the pharmacokinetic/dynamic characteristics of ibuprofen argi …
This review will mainly deal with the clinical pharmacokinetics of ibuprofen arginine, an alternative formulation specifically …
Ibuprofen arginine for pain control during scaling and root planing: a randomized, triple-blind trial.
Ettlin DA, Ettlin A, Bless K, Puhan M, Bernasconi C, Tillmann HC, Palla S, Gallo LM. Ettlin DA, et al. J Clin Periodontol. 2006 May;33(5):345-50. doi: 10.1111/j.1600-051X.2006.00918.x. J Clin Periodontol. 2006. PMID: 16634956 Clinical Trial.
METHODS: This randomized, triple-blind, placebo-controlled, parallel-group trial assessed the analgesic efficacy of ibuprofen arginine (Spedifen) in patients undergoing routine periodontal scaling and root planing. 64 patients with chronic periodontitis recei …
METHODS: This randomized, triple-blind, placebo-controlled, parallel-group trial assessed the analgesic efficacy of ibuprofen argi …
Preliminary pharmacokinetic study of ibuprofen enantiomers after administration of a new oral formulation (ibuprofen arginine) to healthy male volunteers.
Fornasini G, Monti N, Brogin G, Gallina M, Eandi M, Persiani S, Bani M, Della Pepa C, Zara G, Strolin Benedetti M. Fornasini G, et al. Chirality. 1997;9(3):297-302. doi: 10.1002/(SICI)1520-636X(1997)9:3<297::AID-CHIR16>3.0.CO;2-I. Chirality. 1997. PMID: 9176996 Clinical Trial.
The pharmacokinetics of ibuprofen enantiomers were investigated in a crossover study in which seven healthy male volunteers received single oral doses of 800 mg racemic ibuprofen as a soluble granular formulation (sachet) containing L-arginine (designated trade name: Spedifen …
The pharmacokinetics of ibuprofen enantiomers were investigated in a crossover study in which seven healthy male volunteers received single …
Antimicrobial Activity and Cytotoxicity of Nonsteroidal Anti-Inflammatory Drugs against Endodontic Biofilms.
Ferrer-Luque CM, Solana C, Aguado B, Ruiz-Linares M. Ferrer-Luque CM, et al. Antibiotics (Basel). 2023 Feb 23;12(3):450. doi: 10.3390/antibiotics12030450. Antibiotics (Basel). 2023. PMID: 36978317 Free PMC article.
The objective of this work is to evaluate the antimicrobial activity and cytotoxicity of sodium diclofenac (DCS), ibuprofen (IBP) and ibuprofen arginine (IBP-arginine) solutions against endodontic polymicrobial biofilms. ...
The objective of this work is to evaluate the antimicrobial activity and cytotoxicity of sodium diclofenac (DCS), ibuprofen (IBP) and ibu …
Differential Effects of Nonsteroidal Anti-Inflammatory Drugs in an In Vitro Model of Human Leaky Gut.
d'Angelo M, Brandolini L, Catanesi M, Castelli V, Giorgio C, Alfonsetti M, Tomassetti M, Zippoli M, Benedetti E, Cesta MC, Colagioia S, Cocchiaro P, Cimini A, Allegretti M. d'Angelo M, et al. Cells. 2023 Feb 24;12(5):728. doi: 10.3390/cells12050728. Cells. 2023. PMID: 36899865 Free PMC article.
The present study aims to compare the effects of distinct classes of NSAIDs, such as ketoprofen (K), Ibuprofen (IBU), and their corresponding lysine (Lys) and, only for ibuprofen, arginine (Arg) salts, using an in vitro model of leaky gut. ...
The present study aims to compare the effects of distinct classes of NSAIDs, such as ketoprofen (K), Ibuprofen (IBU), and their correspondin …
Spray drying of poorly soluble drugs from aqueous arginine solution.
Ojarinta R, Lerminiaux L, Laitinen R. Ojarinta R, et al. Int J Pharm. 2017 Oct 30;532(1):289-298. doi: 10.1016/j.ijpharm.2017.09.015. Epub 2017 Sep 8. Int J Pharm. 2017. PMID: 28890173
In previous studies, however these mixtures have been produced mainly with small-scale preparation methods, or with methods that have required the use of organic solvents or other dissolution enhancers. In the present study, co-amorphous ibuprofen-arginine and indom …
In previous studies, however these mixtures have been produced mainly with small-scale preparation methods, or with methods that have requir …
Single-Dose Ibuprofen-Arginine as a Preventive for Pain, Edema, and Trismus After Impacted Lower Third Molar Surgery: A Randomized Split-Mouth Clinical Trial.
Ramos EU, Benetti LP, Oliveira JCS, Bassi APF. Ramos EU, et al. Eur J Dent. 2022 May;16(2):396-402. doi: 10.1055/s-0041-1735910. Epub 2021 Dec 22. Eur J Dent. 2022. PMID: 34937107 Free PMC article.
Patients were randomly assigned numbers from 1 to 21. Group A received ibuprofen-arginine as preoperative medication, while Group B received only ibuprofen. ...RESULTS: The study results reveal that the facial edema scores of Group A and Group B presented statistica …
Patients were randomly assigned numbers from 1 to 21. Group A received ibuprofen-arginine as preoperative medication, while Gr …
Influence of Genetic Polymorphisms on the Response to Tramadol, Ibuprofen, and the Combination in Patients With Moderate to Severe Pain After Dental Surgery.
Saiz-Rodríguez M, Valdez-Acosta S, Borobia AM, Burgueño M, Gálvez-Múgica MÁ, Acero J, Cabaleiro T, Muñoz-Guerra MF, Puerro M, Llanos L, Martínez-Pérez D, Ochoa D, Carcas AJ, Abad-Santos F. Saiz-Rodríguez M, et al. Clin Ther. 2021 May;43(5):e86-e102. doi: 10.1016/j.clinthera.2021.03.005. Epub 2021 Apr 1. Clin Ther. 2021. PMID: 33812699 Clinical Trial.
METHODS: The study population comprised 118 patients from a multicenter, randomized, double-blind, placebo-controlled, Phase III clinical trial that assessed the analgesic efficacy and tolerability of a single dose of ibuprofen (arginine)/tramadol 400/37.5 mg compar …
METHODS: The study population comprised 118 patients from a multicenter, randomized, double-blind, placebo-controlled, Phase III clinical tr …
36 results