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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 1
1972 1
1973 1
1974 3
1975 3
1976 2
1977 1
1979 6
1980 19
1981 26
1982 21
1983 20
1984 16
1985 29
1986 19
1987 20
1988 22
1989 36
1990 13
1991 36
1992 35
1993 46
1994 41
1995 55
1996 44
1997 51
1998 56
1999 79
2000 60
2001 80
2002 93
2003 103
2004 154
2005 134
2006 125
2007 184
2008 185
2009 223
2010 250
2011 298
2012 349
2013 408
2014 385
2015 418
2016 441
2017 421
2018 435
2019 411
2020 407
2021 381
2022 343
2023 352
2024 160

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6,667 results

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Page 1
Emerging roles for folate receptor FOLR1 in signaling and cancer.
Nawaz FZ, Kipreos ET. Nawaz FZ, et al. Trends Endocrinol Metab. 2022 Mar;33(3):159-174. doi: 10.1016/j.tem.2021.12.003. Epub 2022 Jan 31. Trends Endocrinol Metab. 2022. PMID: 35094917 Free PMC article. Review.
Folates are B vitamins that function in one-carbon metabolism. Folate receptors are one of three major types of folate transporters. The folate receptors FOLR1 and FOLR2 are overexpressed in multiple cancers. ...
Folates are B vitamins that function in one-carbon metabolism. Folate receptors are one of three major types of fola …
Folate Receptor as a Biomarker and Therapeutic Target in Solid Tumors.
Young O, Ngo N, Lin L, Stanbery L, Creeden JF, Hamouda D, Nemunaitis J. Young O, et al. Curr Probl Cancer. 2023 Feb;47(1):100917. doi: 10.1016/j.currproblcancer.2022.100917. Epub 2022 Nov 17. Curr Probl Cancer. 2023. PMID: 36508886 Free article. Review.
Folate is a B vitamin necessary for basic biological functions, including rapid cell turnover occurring in cancer cell proliferation. Though the role of folate as a causative versus protective agent in carcinogenesis is debated, several studies have indicated that t …
Folate is a B vitamin necessary for basic biological functions, including rapid cell turnover occurring in cancer cell proliferation. …
Targeting the Folate Receptor: Improving Efficacy in Inorganic Medicinal Chemistry.
Carron PM, Crowley A, O'Shea D, McCann M, Howe O, Hunt M, Devereux M. Carron PM, et al. Curr Med Chem. 2018;25(23):2675-2708. doi: 10.2174/0929867325666180209143715. Curr Med Chem. 2018. PMID: 29424300 Review.
The discovery of the high-affinity, high-specificity folate receptor in mamalian kidney cells, coupled with the ability of folate to enter cells by folate receptor-mediated endocytosis and the subsequent elucidation of the folate recep …
The discovery of the high-affinity, high-specificity folate receptor in mamalian kidney cells, coupled with the ability of …
Folate receptor-1 is vital for developmental competence of goat embryos.
Saini S, Ansari S, Sharma V, Saugandhika S, Kumar S, Malakar D. Saini S, et al. Reprod Domest Anim. 2022 May;57(5):541-549. doi: 10.1111/rda.14092. Epub 2022 Feb 16. Reprod Domest Anim. 2022. PMID: 35122705
It is transported into the developing oocytes via folate receptors (FOLR1 and FOLR2) and transporters (RFC1) for utilization during embryo development. However, the role of folate receptors during pre-implantation stages of embryos is not well known. . …
It is transported into the developing oocytes via folate receptors (FOLR1 and FOLR2) and transporters (RFC1) for utilization d …
Folate receptor endocytosis and trafficking.
Sabharanjak S, Mayor S. Sabharanjak S, et al. Adv Drug Deliv Rev. 2004 Apr 29;56(8):1099-109. doi: 10.1016/j.addr.2004.01.010. Adv Drug Deliv Rev. 2004. PMID: 15094209 Review.
Folate absorption is primarily mediated by a membrane transporter with micro-molar affinities for folates. Paradoxically, folates are only present at low nanomolar concentrations in extracellular milieus; membrane folate receptors (FRs) with nan …
Folate absorption is primarily mediated by a membrane transporter with micro-molar affinities for folates. Paradoxically, f …
Folic acid deficiency and vision: a review.
Sijilmassi O. Sijilmassi O. Graefes Arch Clin Exp Ophthalmol. 2019 Aug;257(8):1573-1580. doi: 10.1007/s00417-019-04304-3. Epub 2019 Mar 27. Graefes Arch Clin Exp Ophthalmol. 2019. PMID: 30919078 Review.
Folic acid (FA), also termed folate, is an essential vitamin for health at all ages since it participates in the biosynthesis of nucleotides, amino acids, neurotransmitters, and certain vitamins. ...FA can be transported into the cell by the folate …
Folic acid (FA), also termed folate, is an essential vitamin for health at all ages since it participates in the biosyn …
The folate receptor as a rational therapeutic target for personalized cancer treatment.
Assaraf YG, Leamon CP, Reddy JA. Assaraf YG, et al. Drug Resist Updat. 2014 Oct-Dec;17(4-6):89-95. doi: 10.1016/j.drup.2014.10.002. Epub 2014 Oct 8. Drug Resist Updat. 2014. PMID: 25457975 Review.
Folic acid conjugation is a novel approach for targeting FR-expressing tissues for personalized treatment. With the development of FRalpha-targeted therapies comes a concomitant prerequisite for reliable methods for the quantification of FRalpha tissue expression. T …
Folic acid conjugation is a novel approach for targeting FR-expressing tissues for personalized treatment. With the developmen …
Folate receptor-mediated drug targeting: from therapeutics to diagnostics.
Hilgenbrink AR, Low PS. Hilgenbrink AR, et al. J Pharm Sci. 2005 Oct;94(10):2135-46. doi: 10.1002/jps.20457. J Pharm Sci. 2005. PMID: 16136558 Review.
Due to its small molecular size and high binding affinity for cell surface folate receptors (FR), folate conjugates have the ability to deliver a variety of molecular complexes to pathologic cells without causing harm to normal tissues. Complexes that have be …
Due to its small molecular size and high binding affinity for cell surface folate receptors (FR), folate conjugates hav …
Clinical translation of folate receptor-targeted therapeutics.
Teng L, Xie J, Teng L, Lee RJ. Teng L, et al. Expert Opin Drug Deliv. 2012 Aug;9(8):901-8. doi: 10.1517/17425247.2012.694863. Epub 2012 Jun 5. Expert Opin Drug Deliv. 2012. PMID: 22663189 Review.
INTRODUCTION: Folate receptor-alpha (FR-alpha) has been established as a membrane marker for ovarian cancer. ...Advancement into Phase III trials and the ongoing clinical development of several additional folate conjugates are likely to usher in a new era of …
INTRODUCTION: Folate receptor-alpha (FR-alpha) has been established as a membrane marker for ovarian cancer. ...Advancement in …
6,667 results

Searches related to "folate receptor"