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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 4
1947 2
1948 1
1949 5
1950 4
1951 5
1952 2
1953 10
1954 10
1955 4
1956 7
1957 7
1958 9
1959 6
1960 4
1961 7
1962 5
1963 1
1964 2
1965 2
1975 1
1977 1
1978 2
1984 1
1985 3
1987 5
1988 1
1989 3
1990 3
1991 4
1992 5
1993 24
1994 11
1995 23
1996 33
1997 51
1998 62
1999 127
2000 161
2001 176
2002 172
2003 201
2004 230
2005 248
2006 276
2007 384
2008 385
2009 393
2010 437
2011 502
2012 563
2013 692
2014 667
2015 749
2016 767
2017 740
2018 831
2019 864
2020 942
2021 1051
2022 1039
2023 1047
2024 419

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12,688 results

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Page 1
[Assessment of the significance of dilated perivascular spaces and nocture arterial hypertension in the development of Alzheimer's disease].
Kolmakova KA, Lobzin VY, Emelin AY, Litvinenko IV. Kolmakova KA, et al. Zh Nevrol Psikhiatr Im S S Korsakova. 2024;124(4. Vyp. 2):33-40. doi: 10.17116/jnevro202412404233. Zh Nevrol Psikhiatr Im S S Korsakova. 2024. PMID: 38696149 Russian.
MATERIAL AND METHODS: A total of 119 people, aged 53 to 92 years, including 55 patients with AD, 27 patients with vascular cognitive disorders (VCD), 19 patients with frontotemporal degeneration (FTD). All patients underwent BP monitoring for 24 hours using a standard osci …
MATERIAL AND METHODS: A total of 119 people, aged 53 to 92 years, including 55 patients with AD, 27 patients with vascular cognitive disorde …
Biochemical, Biomarker, and Behavioral Characterization of the Grn(R493X) Mouse Model of Frontotemporal Dementia.
Smith DM, Aggarwal G, Niehoff ML, Jones SA, Banerjee S, Farr SA, Nguyen AD. Smith DM, et al. Mol Neurobiol. 2024 May 2. doi: 10.1007/s12035-024-04190-9. Online ahead of print. Mol Neurobiol. 2024. PMID: 38696065
Heterozygous loss-of-function mutations in the progranulin gene (GRN) are a major cause of frontotemporal dementia due to progranulin haploinsufficiency; complete deficiency of progranulin causes neuronal ceroid lipofuscinosis. ...
Heterozygous loss-of-function mutations in the progranulin gene (GRN) are a major cause of frontotemporal dementia due to prog …
Application and progress of advanced eye movement examinations in cognitive impairment.
Leng Q, Deng B, Ju Y. Leng Q, et al. Front Aging Neurosci. 2024 Apr 17;16:1377406. doi: 10.3389/fnagi.2024.1377406. eCollection 2024. Front Aging Neurosci. 2024. PMID: 38694260 Free PMC article. Review.
This paper extensively reviews various models associated with advanced eye movement examinations and their current applications in cognitive impairment such as Alzheimer's disease, Lewy body dementia and frontotemporal dementia. Advanced eye movement examinat …
This paper extensively reviews various models associated with advanced eye movement examinations and their current applications in cognitive …
Aneuploidy is Linked to Neurological Phenotypes Through Oxidative Stress.
Islam A, Shaukat Z, Hussain R, Ricos MG, Dibbens LM, Gregory SL. Islam A, et al. J Mol Neurosci. 2024 May 2;74(2):50. doi: 10.1007/s12031-024-02227-1. J Mol Neurosci. 2024. PMID: 38693434
A growing body of research from numerous laboratories suggests that many neurodegenerative disorders, especially Alzheimer's disease and frontotemporal dementia, are characterised by neuronal aneuploidy and the ensuing apoptosis, which may contribute to neuronal los …
A growing body of research from numerous laboratories suggests that many neurodegenerative disorders, especially Alzheimer's disease and …
Mutation of the ALS/FTD-associated RNA-binding protein FUS affects axonal development.
Tartwijk FWV, Wunderlich LCS, Mela I, Makarchuk S, Jakobs MAH, Qamar S, Franze K, Schierle GSK, George-Hyslop PHS, Lin JQ, Holt CE, Kaminski CF. Tartwijk FWV, et al. J Neurosci. 2024 May 1:e2148232024. doi: 10.1523/JNEUROSCI.2148-23.2024. Online ahead of print. J Neurosci. 2024. PMID: 38692734
Aberrant condensation and localisation of the RNA-binding protein (RBP) fused in sarcoma (FUS) occur in variants of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Changes in RBP function are commonly associated with changes in axonal cytoskel …
Aberrant condensation and localisation of the RNA-binding protein (RBP) fused in sarcoma (FUS) occur in variants of amyotrophic lateral scle …
Clinical heterogeneity within the ALS-FTD spectrum in a family with a homozygous optineurin mutation.
Parvizi T, Klotz S, Keritam O, Caliskan H, Imhof S, König T, Haider L, Traub-Weidinger T, Wagner M, Brunet T, Brugger M, Zimprich A, Rath J, Stögmann E, Gelpi E, Cetin H. Parvizi T, et al. Ann Clin Transl Neurol. 2024 Apr 30. doi: 10.1002/acn3.52075. Online ahead of print. Ann Clin Transl Neurol. 2024. PMID: 38689506 Free article.
OBJECTIVE: Mutations in the gene encoding for optineurin (OPTN) have been reported in the context of different neurodegenerative diseases including the amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) spectrum. Based on single case reports, neur …
OBJECTIVE: Mutations in the gene encoding for optineurin (OPTN) have been reported in the context of different neurodegenerative diseases in …
Frontotemporal dementia: from genetics to therapeutic approaches.
Buccellato FR, D'Anca M, Tartaglia GM, Del Fabbro M, Galimberti D. Buccellato FR, et al. Expert Opin Investig Drugs. 2024 Apr 30. doi: 10.1080/13543784.2024.2349286. Online ahead of print. Expert Opin Investig Drugs. 2024. PMID: 38687620 Review.
INTRODUCTION: Frontotemporal dementia (FTD) includes a group of neurodegenerative diseases characterized clinically by behavioral disturbances and by neurodegeneration of brain anterior temporal and frontal lobes, leading to atrophy. ...
INTRODUCTION: Frontotemporal dementia (FTD) includes a group of neurodegenerative diseases characterized clinically by behavio …
Glucose hypometabolism prompts RAN translation and exacerbates C9orf72-related ALS/FTD phenotypes.
Nelson AT, Cicardi ME, Markandaiah SS, Han JY, Philp NJ, Welebob E, Haeusler AR, Pasinelli P, Manfredi G, Kawamata H, Trotti D. Nelson AT, et al. EMBO Rep. 2024 Apr 29. doi: 10.1038/s44319-024-00140-7. Online ahead of print. EMBO Rep. 2024. PMID: 38684907 Free article.
The most prevalent genetic cause of both amyotrophic lateral sclerosis and frontotemporal dementia is a (GGGGCC)(n) nucleotide repeat expansion (NRE) occurring in the first intron of the C9orf72 gene (C9). ...
The most prevalent genetic cause of both amyotrophic lateral sclerosis and frontotemporal dementia is a (GGGGCC)(n) nucleotide …
Downstream Biomarker Effects of Gantenerumab or Solanezumab in Dominantly Inherited Alzheimer Disease: The DIAN-TU-001 Randomized Clinical Trial.
Wagemann O, Liu H, Wang G, Shi X, Bittner T, Scelsi MA, Farlow MR, Clifford DB, Supnet-Bell C, Santacruz AM, Aschenbrenner AJ, Hassenstab JJ, Benzinger TLS, Gordon BA, Coalier KA, Cruchaga C, Ibanez L, Perrin RJ, Xiong C, Li Y, Morris JC, Lah JJ, Berman SB, Roberson ED, van Dyck CH, Galasko D, Gauthier S, Hsiung GR, Brooks WS, Pariente J, Mummery CJ, Day GS, Ringman JM, Mendez PC, St George-Hyslop P, Fox NC, Suzuki K, Okhravi HR, Chhatwal J, Levin J, Jucker M, Sims JR, Holdridge KC, Proctor NK, Yaari R, Andersen SW, Mancini M, Llibre-Guerra J, Bateman RJ, McDade E; Dominantly Inherited Alzheimer Network–Trials Unit. Wagemann O, et al. JAMA Neurol. 2024 Apr 29:e240991. doi: 10.1001/jamaneurol.2024.0991. Online ahead of print. JAMA Neurol. 2024. PMID: 38683602 Free PMC article.
Thalamic Alterations in Motor Neuron Diseases: A Systematic Review of MRI Findings.
Mohammadi S, Ghaderi S, Mohammadi M, Najafi Asli Pashaki Z, Khatyal R, Mohammadian F, Mohammadjani S. Mohammadi S, et al. J Integr Neurosci. 2024 Apr 10;23(4):77. doi: 10.31083/j.jin2304077. J Integr Neurosci. 2024. PMID: 38682227 Free article.
The involvement of the thalamus in MNDs, especially in conditions such as amyotrophic lateral sclerosis (ALS), and its interaction with frontotemporal dementia (FTD), has garnered increasing research interest. ...
The involvement of the thalamus in MNDs, especially in conditions such as amyotrophic lateral sclerosis (ALS), and its interaction with f …
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