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Year Number of Results
1961 1
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1970 1
1976 3
1977 1
1978 1
1981 2
1983 5
1984 2
1985 3
1986 1
1987 3
1988 1
1990 3
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1992 3
1993 3
1994 4
1995 1
1997 2
1998 4
1999 5
2000 4
2001 5
2002 3
2003 5
2004 6
2005 10
2006 8
2007 11
2008 11
2009 12
2010 18
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2013 27
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2015 36
2016 31
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2020 33
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2024 9

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504 results

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Page 1
alpha-Asarone, beta-asarone, and gamma-asarone: Current status of toxicological evaluation.
Uebel T, Hermes L, Haupenthal S, Müller L, Esselen M. Uebel T, et al. J Appl Toxicol. 2021 Aug;41(8):1166-1179. doi: 10.1002/jat.4112. Epub 2020 Nov 25. J Appl Toxicol. 2021. PMID: 33236787 Review.
They are further chemically classified into the propenylic trans- and cis-isomers alpha-asarone and beta-asarone and the allylic gamma-asarone. Flavoring, as well as potentially pharmacologically useful properties, enables the application of asarone …
They are further chemically classified into the propenylic trans- and cis-isomers alpha-asarone and beta-asarone and the allyl …
Pharmacology and toxicology of alpha- and beta-Asarone: A review of preclinical evidence.
Chellian R, Pandy V, Mohamed Z. Chellian R, et al. Phytomedicine. 2017 Aug 15;32:41-58. doi: 10.1016/j.phymed.2017.04.003. Epub 2017 Apr 11. Phytomedicine. 2017. PMID: 28732807 Review.
In preclinical studies, both alpha- and beta-asarone have been reported to have numerous pharmacological activities and at the same time, many studies have also revealed the toxicity of alpha- and beta-asarone. ...Moreover, further dose-dependent in vivo studies are …
In preclinical studies, both alpha- and beta-asarone have been reported to have numerous pharmacological activities and at the same t …
Alpha-Asarone modulates kynurenine disposal in muscle and mediates resilience to stress-induced depression via PGC-1alpha induction.
Yan L, Liu CH, Xu L, Qian YY, Song PP, Wei M, Liu BL. Yan L, et al. CNS Neurosci Ther. 2023 Mar;29(3):941-956. doi: 10.1111/cns.14030. Epub 2022 Dec 27. CNS Neurosci Ther. 2023. PMID: 36575869 Free PMC article.
METHODS: The antidepressant effects of alpha-asarone were evaluated in chronic mild stress (CMS) and muscle-specific PGC-1alpha-deficient mice. ...In support, the antidepressant effect of alpha-asarone was diminished by muscle-specific PGC-1alpha deficient mice subj …
METHODS: The antidepressant effects of alpha-asarone were evaluated in chronic mild stress (CMS) and muscle-specific PGC-1alpha-defic …
beta-asarone improves cognitive impairment and alleviates autophagy in mice with vascular dementia via the cAMP/PKA/CREB pathway.
Ning Z, Zhong X, Wu Y, Wang Y, Hu D, Wang K, Deng M. Ning Z, et al. Phytomedicine. 2024 Jan;123:155215. doi: 10.1016/j.phymed.2023.155215. Epub 2023 Nov 25. Phytomedicine. 2024. PMID: 38039902
We also reported that beta-asarone improves learning and memory. This study further clarifies whether beta-asarone attenuates cerebral ischaemic injury by acting through the cAMP/PKA/CREB pathway in VD model mice. ...Moreover, beta-asarone downregulated VD-in …
We also reported that beta-asarone improves learning and memory. This study further clarifies whether beta-asarone attenuates …
beta-Asarone Ameliorates beta-Amyloid-Induced Neurotoxicity in PC12 Cells by Activating P13K/Akt/Nrf2 Signaling Pathway.
Meng M, Zhang L, Ai D, Wu H, Peng W. Meng M, et al. Front Pharmacol. 2021 May 10;12:659955. doi: 10.3389/fphar.2021.659955. eCollection 2021. Front Pharmacol. 2021. PMID: 34040526 Free PMC article.
In this study, we used an Abeta-stimulated PC12 cell model to explore the neuroprotective effects and potential mechanisms of beta-asarone. The results showed that beta-asarone could improve cell viability and weaken cell damage and apoptosis. beta-asarone co …
In this study, we used an Abeta-stimulated PC12 cell model to explore the neuroprotective effects and potential mechanisms of beta-asaron …
Protective effect of alpha-asarone against nicotine-induced seizures in mice, but not by its interaction with nicotinic acetylcholine receptors.
Chellian R, Pandy V. Chellian R, et al. Biomed Pharmacother. 2018 Dec;108:1591-1595. doi: 10.1016/j.biopha.2018.09.137. Epub 2018 Oct 9. Biomed Pharmacother. 2018. PMID: 30372861 Free article.
In our recent study, alpha-asarone attenuated the nicotine withdrawal-induced depression-like behavior in mice. ...In this study, we investigated the effect of alpha-asarone on the locomotor activity and body temperature in mice. In addition, we studied the effect o …
In our recent study, alpha-asarone attenuated the nicotine withdrawal-induced depression-like behavior in mice. ...In this study, we …
beta-asarone inhibits the migration, invasion, and EMT of bladder cancer through activating ER stress.
Liu B, Dan W, Wei Y, Zhang Y, Wang C, Lei Y, Hou T, Zhang Y, Gao Y. Liu B, et al. Cancer Med. 2023 Jun;12(12):13610-13622. doi: 10.1002/cam4.6059. Epub 2023 Jun 12. Cancer Med. 2023. PMID: 37306628 Free PMC article.
BACKGROUND: beta-asarone (beta-as), a compound extracted from Acorus calamus, has been found to have anticancer effects on a variety of human cancers. ...
BACKGROUND: beta-asarone (beta-as), a compound extracted from Acorus calamus, has been found to have anticancer effects on a variety …
beta-Asarone Alleviates High-Glucose-Induced Oxidative Damage via Inhibition of ROS Generation and Inactivation of the NF-kappaB/NLRP3 Inflammasome Pathway in Human Retinal Pigment Epithelial Cells.
Park C, Cha HJ, Hwangbo H, Bang E, Hong SH, Song KS, Noh JS, Kim DH, Kim GY, Choi YH. Park C, et al. Antioxidants (Basel). 2023 Jul 11;12(7):1410. doi: 10.3390/antiox12071410. Antioxidants (Basel). 2023. PMID: 37507949 Free PMC article.
In this study, we investigated whether beta-asarone inhibits high-glucose (HG)-induced oxidative damage in human retinal pigment epithelial (RPE) ARPE-19 cells. ...However, their expression levels remained similar to those in the control group in the presence of beta-as …
In this study, we investigated whether beta-asarone inhibits high-glucose (HG)-induced oxidative damage in human retinal pigment epit …
beta-asarone prolongs sleep via regulating the level of glutamate in the PVN.
Liu H, Zhou R, Yin L, Si N, Yang C, Huang C, Wang R, Chen X. Liu H, et al. Biochem Biophys Res Commun. 2023 Jul 12;665:71-77. doi: 10.1016/j.bbrc.2023.05.010. Epub 2023 May 2. Biochem Biophys Res Commun. 2023. PMID: 37149985
In the study, adult male C57BL/6 mice were administered beta-asarone at 12.5 mg/kg, 25 mg/kg, and 50 mg/kg. Behavioral experiments showed that beta-asarone at 25 mg/kg could significantly improve sleep duration. ...This study is the first to focus on the association …
In the study, adult male C57BL/6 mice were administered beta-asarone at 12.5 mg/kg, 25 mg/kg, and 50 mg/kg. Behavioral experiments sh …
504 results