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grflox
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Deletion of mesenchymal glucocorticoid receptor attenuates embryonic lung development and abdominal wall closure.
PLoS One. 2013 May 16;8(5):e63578. doi: 10.1371/journal.pone.0063578. Print 2013.
PLoS One. 2013.
PMID: 23696835
Free PMC article.
In the present study, we investigated the role of the GR during embryogenesis specifically in mesenchymal tissues. To this aim, we crossed GRflox mice with Dermo1-Cre mice to generate GR(Dermo1) mice, where the GR gene was deleted within mesenchymal cells. ...
In the present study, we investigated the role of the GR during embryogenesis specifically in mesenchymal tissues. To this aim, we crossed …
Impaired resolution of DSS-induced colitis in mice lacking the glucocorticoid receptor in myeloid cells.
Meers GK, Bohnenberger H, Reichardt HM, Lühder F, Reichardt SD.
Meers GK, et al.
PLoS One. 2018 Jan 11;13(1):e0190846. doi: 10.1371/journal.pone.0190846. eCollection 2018.
PLoS One. 2018.
PMID: 29324769
Free PMC article.
While clinical symptoms and tissue damage in the colon ameliorated again in GRflox mice, the disease further aggravated in GRlysM littermates. ...
While clinical symptoms and tissue damage in the colon ameliorated again in GRflox mice, the disease further aggravated in GRlysM lit …
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The glucocorticoid receptor in monocyte-derived macrophages is critical for cardiac infarct repair and remodeling.
Galuppo P, Vettorazzi S, Hövelmann J, Scholz CJ, Tuckermann JP, Bauersachs J, Fraccarollo D.
Galuppo P, et al.
FASEB J. 2017 Nov;31(11):5122-5132. doi: 10.1096/fj.201700317R. Epub 2017 Aug 2.
FASEB J. 2017.
PMID: 28768721
Free PMC article.
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Critical role of macrophages in glucocorticoid driven vascular calcification in a mouse-model of atherosclerosis.
Preusch MR, Rattazzi M, Albrecht C, Merle U, Tuckermann J, Schütz G, Blessing E, Zoppellaro G, Pauletto P, Krempien R, Rosenfeld ME, Katus HA, Bea F.
Preusch MR, et al.
Arterioscler Thromb Vasc Biol. 2008 Dec;28(12):2158-64. doi: 10.1161/ATVBAHA.108.174128. Epub 2008 Sep 11.
Arterioscler Thromb Vasc Biol. 2008.
PMID: 18787189
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