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Globularia alypum L. and Related Species: LC-MS Profiles and Antidiabetic, Antioxidant, Anti-Inflammatory, Antibacterial and Anticancer Potential.
Friščić M, Petlevski R, Kosalec I, Madunić J, Matulić M, Bucar F, Hazler Pilepić K, Maleš Ž. Friščić M, et al. Pharmaceuticals (Basel). 2022 Apr 21;15(5):506. doi: 10.3390/ph15050506. Pharmaceuticals (Basel). 2022. PMID: 35631332 Free PMC article.
Species from the genus Globularia L. have been used as healing agents for various ailments, with utilization of Globularia alypum L. being most frequently reported. ...G. punctata, G. cordifolia and G. meridionalis showed greater anticancer potential than G. …
Species from the genus Globularia L. have been used as healing agents for various ailments, with utilization of Globularia
Globularia alypum Extracts Attenuate Hyperglycemia and Protect against Various Organ Toxicities in Alloxan-Induced Experimental Diabetic Rats.
Tiss M, Hamden K. Tiss M, et al. Evid Based Complement Alternat Med. 2022 Aug 30;2022:6816942. doi: 10.1155/2022/6816942. eCollection 2022. Evid Based Complement Alternat Med. 2022. PMID: 36082185 Free PMC article.
In this study, we attempted for the first time to determine the phytochemical compositions and biopharmaceutical properties of Globularia alypum methanol extract (GAME) and Globularia alypum water extract (GAWE). ...
In this study, we attempted for the first time to determine the phytochemical compositions and biopharmaceutical properties of Globularia
Globularia alypum L. Modulates Inflammatory Markers in Human Colon and Shows a Potential Antioxidant Role in Myeloid Leukemic Cells.
Hajji N, Hudik E, Iovino P, Zouari N, Sebai H, Nusse O, Ciacci C. Hajji N, et al. Transl Med UniSa. 2021 Dec 23;24(1):13-23. doi: 10.37825/2239-9754.1030. eCollection 2021. Transl Med UniSa. 2021. PMID: 36447742 Free PMC article.
Globularia alypum (GA), a plant of the Globulariacea family, has long been used as a traditional cure for inflammatory and metabolic illnesses. ...
Globularia alypum (GA), a plant of the Globulariacea family, has long been used as a traditional cure for inflammatory and met
Phytochemical Investigation and Antioxidant Activity of Globularia alypum L.
Asraoui F, Kounnoun A, Cadi HE, Cacciola F, Majdoub YOE, Alibrando F, Mandolfino F, Dugo P, Mondello L, Louajri A. Asraoui F, et al. Molecules. 2021 Feb 2;26(3):759. doi: 10.3390/molecules26030759. Molecules. 2021. PMID: 33540622 Free PMC article.
The present study was designed to investigate the total phenolic and flavonoid contents, as well as the antioxidant properties of leaves extracts from Globularia alypum L. colected from the Taza region in northeast Morocco. ...
The present study was designed to investigate the total phenolic and flavonoid contents, as well as the antioxidant properties of leaves ext …
Anti-obesity, anti-hyperglycaemic, anti-antipyretic and analgesic activities of Globularia alypum extracts.
Mohamed T, Souiy Z, Achour L, Hamden K. Mohamed T, et al. Arch Physiol Biochem. 2022 Dec;128(6):1453-1460. doi: 10.1080/13813455.2020.1773865. Epub 2020 Jun 13. Arch Physiol Biochem. 2022. PMID: 32536285
OBJECTIVES: The aim of this study is to evaluate the anti-obesity, anti-hyperglycaemic, analgesic and antipyretic activities of Globularia alypum (GA). MATERIALS AND METHODS: GA methanol and water extracts (GAME, GAWE) were administered to high-fat-high-glucose diet …
OBJECTIVES: The aim of this study is to evaluate the anti-obesity, anti-hyperglycaemic, analgesic and antipyretic activities of Globulari
The Role of Globularia alypum Explored Ex Vivo In Vitro on Human Colon Biopsies from Ulcerative Colitis Patients.
Hajji N, Russo I, Bianco J, Piazza O, Iovino P, Santonicola A, Ciacci C. Hajji N, et al. Nutrients. 2023 Mar 17;15(6):1457. doi: 10.3390/nu15061457. Nutrients. 2023. PMID: 36986188 Free PMC article.
The existing literature indicates that Globularia alypum L. (GA) influences inflammation and oxidative stress modulation in rats and in vitro. ...
The existing literature indicates that Globularia alypum L. (GA) influences inflammation and oxidative stress modulation in ra …
Globularia alypum L. extracts reduced histamine and serotonin contraction in vitro.
Bello R, Moreno L, Primo-Yúfera E, Esplugues J. Bello R, et al. Phytother Res. 2002 Jun;16(4):389-92. doi: 10.1002/ptr.918. Phytother Res. 2002. PMID: 12112300
The present study analyses in in vitro models the pharmacological activity of methanol and dichloromethane extracts (1, 10 and 100 microg/mL) obtained from the leaves and stems of Globularia alypum L. Preincubation of the guinea-pig ileum and rat uterus with both ex …
The present study analyses in in vitro models the pharmacological activity of methanol and dichloromethane extracts (1, 10 and 100 microg/mL …
Purgative/laxative actions of Globularia alypum aqueous extract on gastrointestinal-physiological function and against loperamide-induced constipation coupled to oxidative stress and inflammation in rats.
Hajji N, Wannes D, Jabri MA, Rtibi K, Tounsi H, Abdellaoui A, Sebai H. Hajji N, et al. Neurogastroenterol Motil. 2020 Aug;32(8):e13858. doi: 10.1111/nmo.13858. Epub 2020 Apr 26. Neurogastroenterol Motil. 2020. PMID: 32337785
Therefore, many studies were oriented to search herbal laxative agents. In this study, we investigated the effect of Globularia alypum L. leaves aqueous extract (GAAE) against loperamide (LOP)-produced constipation. ...
Therefore, many studies were oriented to search herbal laxative agents. In this study, we investigated the effect of Globularia al
HPLC-DAD Analysis and Investigation of Biological Properties of the Leaves of Globularia alypum (L.), Infusion Extract.
Nouir S, Laouani A, Loghmari A, Bouassida K, Slim R, Bouhajeb R, Hasni Y, Saguem K, Ouni B, Zaïri A. Nouir S, et al. Pharmaceuticals (Basel). 2023 Dec 14;16(12):1726. doi: 10.3390/ph16121726. Pharmaceuticals (Basel). 2023. PMID: 38139852 Free PMC article.
Globularia alypum L. (GA) belonging to the Globulariaceae family is a Mediterranean plant which is widely used in traditional Tunisian medicine. ...
Globularia alypum L. (GA) belonging to the Globulariaceae family is a Mediterranean plant which is widely used in traditional
Globularia alypum aqueous extract decreases hypertriglyceridemia and ameliorates oxidative status of the muscle, kidney, and heart in rats fed a high-fructose diet.
Taleb-Dida N, Krouf D, Bouchenak M. Taleb-Dida N, et al. Nutr Res. 2011 Jun;31(6):488-95. doi: 10.1016/j.nutres.2011.05.005. Nutr Res. 2011. PMID: 21745631
Moreover, the beneficial health effects of plant polyphenols are frequently attributed to their potent antioxidant effects. We hypothesized that administration of Globularia alypum (Ga) aqueous extract would reduce metabolic disorders and oxidative stress induced in …
Moreover, the beneficial health effects of plant polyphenols are frequently attributed to their potent antioxidant effects. We hypothesized …
45 results