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Year Number of Results
1964 1
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1987 16
1988 14
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2024 150

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4,063 results

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Page 1
Did you mean gluco (1,842 results)?
Alpha glucosidase inhibitors.
Kalra S. Kalra S. J Pak Med Assoc. 2014 Apr;64(4):474-6. J Pak Med Assoc. 2014. PMID: 24864650
Important Aspects of Post-Prandial Antidiabetic Drug, Acarbose.
Singla RK, Singh R, Dubey AK. Singla RK, et al. Curr Top Med Chem. 2016;16(23):2625-33. doi: 10.2174/1568026616666160414123500. Curr Top Med Chem. 2016. PMID: 27086787 Review.
Acarbose, a well known and efficacious alpha-amylase and alpha-glucosidase inhibitor, is a postprandial acting antidiabetic drug. DNS-based alpha-amylase inhibitory assays showed that use of acarbose at concentrations above 125 g/ml resulted in release of reducing s …
Acarbose, a well known and efficacious alpha-amylase and alpha-glucosidase inhibitor, is a postprandial acting antidiabetic drug. DNS …
Hypoglycemia post bariatric surgery: drugs with different mechanisms of action to treat a unique disorder.
Carpentieri GB, Gonçalves SEAB, Mourad WM, Pinto LGC, Zanella MT. Carpentieri GB, et al. Arch Endocrinol Metab. 2023 Mar 30;67(3):442-449. doi: 10.20945/2359-3997000000598. Epub 2023 Feb 7. Arch Endocrinol Metab. 2023. PMID: 36748934 Free PMC article. Review.
In this review, we gathered articles on PPH after BS from PubMed searches (2001 to 2022) and focused on the main drugs tested for the treatment of this condition, such as acarbose, somatostatin analogues, type 2 sodium-glucose cotransporter inhibitors, calcium channel bloc …
In this review, we gathered articles on PPH after BS from PubMed searches (2001 to 2022) and focused on the main drugs tested for the treatm …
The biosynthesis of acarbose and validamycin.
Mahmud T, Lee S, Floss HG. Mahmud T, et al. Chem Rec. 2001;1(4):300-10. doi: 10.1002/tcr.1015. Chem Rec. 2001. PMID: 11893070 Review.
The deoxyhexose moiety of acarbose arises from glucose with deoxythymidyl-diphospho-4-keto-6-deoxy-D-glucose (dTDP-4-keto-6-deoxy-D-glucose) as a proximate intermediate. However, despite the identical origin of the aminocyclitol moieties in acarbose and validamycin …
The deoxyhexose moiety of acarbose arises from glucose with deoxythymidyl-diphospho-4-keto-6-deoxy-D-glucose (dTDP-4-keto-6-deoxy-D-g …
Acarbose suppresses symptoms of mitochondrial disease in a mouse model of Leigh syndrome.
Bitto A, Grillo AS, Ito TK, Stanaway IB, Nguyen BMG, Ying K, Tung H, Smith K, Tran N, Velikanje G, Urfer SR, Snyder JM, Barton J, Sharma A, Kayser EB, Wang L, Smith DL Jr, Thompson JW, DuBois L, DePaolo W, Kaeberlein M. Bitto A, et al. Nat Metab. 2023 Jun;5(6):955-967. doi: 10.1038/s42255-023-00815-w. Epub 2023 Jun 26. Nat Metab. 2023. PMID: 37365290
Unlike rapamycin, acarbose rescues disease phenotypes independently of inhibition of the mechanistic target of rapamycin. ...We find that acarbose remodels the intestinal microbiome and alters the production of short-chain fatty acids. ...
Unlike rapamycin, acarbose rescues disease phenotypes independently of inhibition of the mechanistic target of rapamycin. ...We find …
Calorie Restriction Mimetics: Upstream-Type Compounds for Modulating Glucose Metabolism.
Shintani H, Shintani T, Ashida H, Sato M. Shintani H, et al. Nutrients. 2018 Nov 22;10(12):1821. doi: 10.3390/nu10121821. Nutrients. 2018. PMID: 30469486 Free PMC article. Review.
Among these, we focus on upstream-type CRMs and propose their classification as compounds with energy metabolism inhibition effects, particularly glucose metabolism modulation effects. The upstream-type CRMs reviewed include chitosan, acarbose, sodium-glucose cotransporter …
Among these, we focus on upstream-type CRMs and propose their classification as compounds with energy metabolism inhibition effects, particu …
The inhibitory effects of flavonoids on α-amylase and α-glucosidase.
Zhu J, Chen C, Zhang B, Huang Q. Zhu J, et al. Crit Rev Food Sci Nutr. 2020;60(4):695-708. doi: 10.1080/10408398.2018.1548428. Epub 2019 Jan 13. Crit Rev Food Sci Nutr. 2020. PMID: 30638035 Review.
The objective of this review is to summarize knowledge on the inhibitory effects (IEs) of flavonoids on alpha-amylase (alphaA) and alpha-glucosidase (alphaG) relevant to the search of substitutes of acarbose (Aca). Flavonoids reported to be more effective at inhibiting alp …
The objective of this review is to summarize knowledge on the inhibitory effects (IEs) of flavonoids on alpha-amylase (alphaA) and alpha-glu …
Clinical and genetic predictors of diabetes drug's response.
Fodor A, Cozma A, Suharoschi R, Sitar-Taut A, Roman G. Fodor A, et al. Drug Metab Rev. 2019 Nov;51(4):408-427. doi: 10.1080/03602532.2019.1656226. Epub 2019 Aug 28. Drug Metab Rev. 2019. PMID: 31456442 Review.
Lifespan benefits for the combination of rapamycin plus acarbose and for captopril in genetically heterogeneous mice.
Strong R, Miller RA, Cheng CJ, Nelson JF, Gelfond J, Allani SK, Diaz V, Dorigatti AO, Dorigatti J, Fernandez E, Galecki A, Ginsburg B, Hamilton KL, Javors MA, Kornfeld K, Kaeberlein M, Kumar S, Lombard DB, Lopez-Cruzan M, Miller BF, Rabinovitch P, Reifsnyder P, Rosenthal NA, Bogue MA, Salmon AB, Suh Y, Verdin E, Weissbach H, Newman J, Maccchiarini F, Harrison DE. Strong R, et al. Aging Cell. 2022 Dec;21(12):e13724. doi: 10.1111/acel.13724. Epub 2022 Sep 30. Aging Cell. 2022. PMID: 36179270 Free PMC article.
Mice bred in 2017 and entered into the C2017 cohort were tested for possible lifespan benefits of (R/S)-1,3-butanediol (BD), captopril (Capt), leucine (Leu), the Nrf2-activating botanical mixture PB125, sulindac, syringaresinol, or the combination of rapamycin and acarbose …
Mice bred in 2017 and entered into the C2017 cohort were tested for possible lifespan benefits of (R/S)-1,3-butanediol (BD), captopril (Capt …
4,063 results