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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 1
1977 1
1978 2
1979 1
1981 1
1982 1
1983 1
1984 1
1985 1
1987 1
1988 6
1989 7
1990 6
1991 5
1992 13
1993 10
1994 20
1995 18
1996 23
1997 21
1998 29
1999 26
2000 27
2001 22
2002 24
2003 29
2004 25
2005 40
2006 43
2007 39
2008 47
2009 37
2010 28
2011 39
2012 53
2013 49
2014 56
2015 62
2016 52
2017 50
2018 48
2019 43
2020 58
2021 52
2022 43
2023 48
2024 16

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1,078 results

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Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
A Randomized Trial of Enteral Glutamine for Treatment of Burn Injuries.
Heyland DK, Wibbenmeyer L, Pollack J, Friedman B, Turgeon AF, Eshraghi N, Jeschke MG, Bélisle S, Grau D, Mandell S, Velamuri SR, Hundeshagen G, Moiemen N, Shokrollahi K, Foster K, Huss F, Collins D, Savetamal A, Gurney JM, Depetris N, Stoppe C, Ortiz-Reyes L, Garrel D, Day AG; RE-ENERGIZE Trial Team. Heyland DK, et al. N Engl J Med. 2022 Sep 15;387(11):1001-1010. doi: 10.1056/NEJMoa2203364. Epub 2022 Sep 9. N Engl J Med. 2022. PMID: 36082909 Clinical Trial.
BACKGROUND: Glutamine is thought to have beneficial effects on the metabolic and stress response to severe injury. ...Mortality at 6 months was 17.2% in the glutamine group and 16.2% in the placebo group (hazard ratio for death, 1.06; 95% CI, 0.80 to 1.41). ...
BACKGROUND: Glutamine is thought to have beneficial effects on the metabolic and stress response to severe injury. ...Mortality at 6 …
Randomised placebo-controlled trial of dietary glutamine supplements for postinfectious irritable bowel syndrome.
Zhou Q, Verne ML, Fields JZ, Lefante JJ, Basra S, Salameh H, Verne GN. Zhou Q, et al. Gut. 2019 Jun;68(6):996-1002. doi: 10.1136/gutjnl-2017-315136. Epub 2018 Aug 14. Gut. 2019. PMID: 30108163 Free PMC article. Clinical Trial.
METHODS: Eligible adults were randomised to glutamine (5 g/t.i.d.) or placebo for 8 weeks. The primary end point was a reduction of 50 points on the Irritable Bowel Syndrome Severity Scoring System (IBS-SS). Secondary endpoints included: raw IBS-SS scores, changes in daily …
METHODS: Eligible adults were randomised to glutamine (5 g/t.i.d.) or placebo for 8 weeks. The primary end point was a reduction of 5 …
The Effect of Amino Acids on Wound Healing: A Systematic Review and Meta-Analysis on Arginine and Glutamine.
Arribas-López E, Zand N, Ojo O, Snowden MJ, Kochhar T. Arribas-López E, et al. Nutrients. 2021 Jul 22;13(8):2498. doi: 10.3390/nu13082498. Nutrients. 2021. PMID: 34444657 Free PMC article.
This study aims to perform a systematic review and meta-analysis of the effect of arginine and glutamine supplementation on wound healing. PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines were followed for the systematic review and ten …
This study aims to perform a systematic review and meta-analysis of the effect of arginine and glutamine supplementation on wound hea …
The effect of glutamine supplementation on athletic performance, body composition, and immune function: A systematic review and a meta-analysis of clinical trials.
Ramezani Ahmadi A, Rayyani E, Bahreini M, Mansoori A. Ramezani Ahmadi A, et al. Clin Nutr. 2019 Jun;38(3):1076-1091. doi: 10.1016/j.clnu.2018.05.001. Epub 2018 May 9. Clin Nutr. 2019. PMID: 29784526
There was no association between glutamine ingestion and other outcomes investigated. CONCLUSION: According to this meta-analysis, generally, glutamine supplementation has no effect on athletics immune system, aerobic performance, and body composition. However, the …
There was no association between glutamine ingestion and other outcomes investigated. CONCLUSION: According to this meta-analysis, ge …
A Phase 3 Trial of l-Glutamine in Sickle Cell Disease.
Niihara Y, Miller ST, Kanter J, Lanzkron S, Smith WR, Hsu LL, Gordeuk VR, Viswanathan K, Sarnaik S, Osunkwo I, Guillaume E, Sadanandan S, Sieger L, Lasky JL, Panosyan EH, Blake OA, New TN, Bellevue R, Tran LT, Razon RL, Stark CW, Neumayr LD, Vichinsky EP; Investigators of the Phase 3 Trial of l-Glutamine in Sickle Cell Disease. Niihara Y, et al. N Engl J Med. 2018 Jul 19;379(3):226-235. doi: 10.1056/NEJMoa1715971. N Engl J Med. 2018. PMID: 30021096 Free article. Clinical Trial.
RESULTS: A total of 230 patients (age range, 5 to 58 years; 53.9% female) were randomly assigned, in a 2:1 ratio, to receive l-glutamine (152 patients) or placebo (78 patients). The patients in the l-glutamine group had significantly fewer pain crises than those in …
RESULTS: A total of 230 patients (age range, 5 to 58 years; 53.9% female) were randomly assigned, in a 2:1 ratio, to receive l-glutamine …
A randomized trial of glutamine and antioxidants in critically ill patients.
Heyland D, Muscedere J, Wischmeyer PE, Cook D, Jones G, Albert M, Elke G, Berger MM, Day AG; Canadian Critical Care Trials Group. Heyland D, et al. N Engl J Med. 2013 Apr 18;368(16):1489-97. doi: 10.1056/NEJMoa1212722. N Engl J Med. 2013. PMID: 23594003 Free article. Clinical Trial.
RESULTS: There was a trend toward increased mortality at 28 days among patients who received glutamine as compared with those who did not receive glutamine (32.4% vs. 27.2%; adjusted odds ratio, 1.28; 95% confidence interval [CI], 1.00 to 1.64; P=0.05). In-hospital …
RESULTS: There was a trend toward increased mortality at 28 days among patients who received glutamine as compared with those who did …
Randomized double-blind, placebo-controlled trial evaluating oral glutamine on radiation-induced oral mucositis and dermatitis in head and neck cancer patients.
Huang CJ, Huang MY, Fang PT, Chen F, Wang YT, Chen CH, Yuan SS, Huang CM, Luo KH, Chuang HY, Wang YY, Lee HH. Huang CJ, et al. Am J Clin Nutr. 2019 Mar 1;109(3):606-614. doi: 10.1093/ajcn/nqy329. Am J Clin Nutr. 2019. PMID: 30753262 Free PMC article. Clinical Trial.
BACKGROUND: Glutamine is the primary fuel for the gastrointestinal epithelium and maintains the mucosal structure. ...The patients, care providers, and investigators were blinded to the group assignment. Eligible patients received either oral glutamine (5 g gluta …
BACKGROUND: Glutamine is the primary fuel for the gastrointestinal epithelium and maintains the mucosal structure. ...The patients, c …
Glutamine supplementation to prevent morbidity and mortality in preterm infants.
Moe-Byrne T, Brown JV, McGuire W. Moe-Byrne T, et al. Cochrane Database Syst Rev. 2016 Apr 18;4(4):CD001457. doi: 10.1002/14651858.CD001457.pub6. Cochrane Database Syst Rev. 2016. PMID: 27089158 Free PMC article. Review.
It has been suggested that glutamine supplementation may also benefit preterm infants. OBJECTIVES: To determine the effects of glutamine supplementation on mortality and morbidity in preterm infants. ...SELECTION CRITERIA: Randomised or quasi-randomised controlled t …
It has been suggested that glutamine supplementation may also benefit preterm infants. OBJECTIVES: To determine the effects of glu …
Glutamine supplementation to prevent morbidity and mortality in preterm infants.
Moe-Byrne T, Brown JV, McGuire W. Moe-Byrne T, et al. Cochrane Database Syst Rev. 2016 Jan 12;(1):CD001457. doi: 10.1002/14651858.CD001457.pub5. Cochrane Database Syst Rev. 2016. PMID: 26755330 Free article. Updated. Review.
It has been suggested that glutamine supplementation may also benefit preterm infants. OBJECTIVES: To determine the effects of glutamine supplementation on mortality and morbidity in preterm infants. ...SELECTION CRITERIA: Randomised or quasi-randomised controlled t …
It has been suggested that glutamine supplementation may also benefit preterm infants. OBJECTIVES: To determine the effects of glu …
Effect of glutamine supplementation on inflammatory markers in critically ill patients supported with enteral or parenteral feeding.
Gholamalizadeh M, Tabrizi R, Rezaei S, Badeli M, Shadnoush M, Jarrahi AM, Doaei S. Gholamalizadeh M, et al. JPEN J Parenter Enteral Nutr. 2022 Jan;46(1):61-68. doi: 10.1002/jpen.2217. Epub 2021 Aug 16. JPEN J Parenter Enteral Nutr. 2022. PMID: 34213769 Review.
BACKGROUND: Glutamine plays an important role in acute catabolic conditions in critically ill patients. ...All randomized clinical trials that assessed the effect of glutamine supplementation on "inflammatory markers" in EN or PN were included in the study. ...
BACKGROUND: Glutamine plays an important role in acute catabolic conditions in critically ill patients. ...All randomized clinical tr …
1,078 results

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