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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1960 1
1964 2
1966 2
1967 4
1968 4
1969 1
1970 2
1971 3
1972 3
1973 4
1974 3
1975 7
1976 7
1977 5
1978 13
1979 9
1980 20
1981 17
1982 31
1983 22
1984 44
1985 24
1986 37
1987 41
1988 40
1989 35
1990 51
1991 49
1992 72
1993 60
1994 92
1995 92
1996 110
1997 100
1998 115
1999 114
2000 138
2001 132
2002 150
2003 147
2004 145
2005 212
2006 179
2007 180
2008 199
2009 181
2010 198
2011 216
2012 234
2013 278
2014 272
2015 296
2016 241
2017 253
2018 296
2019 297
2020 316
2021 269
2022 286
2023 279
2024 105

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5,990 results

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Page 1
Hepatic TGFβr1 Deficiency Attenuates Lipopolysaccharide/D-Galactosamine-Induced Acute Liver Failure Through Inhibiting GSK3β-Nrf2-Mediated Hepatocyte Apoptosis and Ferroptosis.
Huang S, Wang Y, Xie S, Lai Y, Mo C, Zeng T, Kuang S, Deng G, Zhou C, Chen Y, Huang S, Gao L, Lv Z. Huang S, et al. Cell Mol Gastroenterol Hepatol. 2022;13(6):1649-1672. doi: 10.1016/j.jcmgh.2022.02.009. Epub 2022 Feb 21. Cell Mol Gastroenterol Hepatol. 2022. PMID: 35202887 Free PMC article.
BACKGROUND & AIMS: Acute liver failure (ALF) is a condition with high mortality and morbidity, characterized by glutathione depletion, oxidative stress, and mitochondrial dysfunction. ...We also noticed that liver TGFbetar1 deficiency alleviated LPS/D-GalN-induced apop …
BACKGROUND & AIMS: Acute liver failure (ALF) is a condition with high mortality and morbidity, characterized by glutathione deple …
Effects of paralytic shellfish toxins on the middle intestine of Oncorhynchus mykiss: Glutathione metabolism, oxidative status, lysosomal function and ATP-binding cassette class C (ABCC) proteins activity.
Painefilú JC, Bianchi VA, Krock B, De Anna JS, Kristoff G, Luquet CM. Painefilú JC, et al. Ecotoxicol Environ Saf. 2020 Nov;204:111069. doi: 10.1016/j.ecoenv.2020.111069. Epub 2020 Aug 3. Ecotoxicol Environ Saf. 2020. PMID: 32758696
We studied the absorption, cytotoxicity and oxidative stress markers of Paralytic Shellfish Toxins (PST) from three extracts from Alexandrium catenella and A. ostenfeldii, in middle Oncorhynchus mykiss intestine in vitro and ex vivo preparations. We measured glutathione …
We studied the absorption, cytotoxicity and oxidative stress markers of Paralytic Shellfish Toxins (PST) from three extracts from Ale …
Glutathione and glutathione analogues; therapeutic potentials.
Wu JH, Batist G. Wu JH, et al. Biochim Biophys Acta. 2013 May;1830(5):3350-3. doi: 10.1016/j.bbagen.2012.11.016. Epub 2012 Nov 28. Biochim Biophys Acta. 2013. PMID: 23201199 Review.
BACKGROUND: Glutathione (GSH) and related enzymes are critical to cell protection from toxins, both endogenous and environmental, including a number of anti-cancer cytotoxic agents. ...This article is part of a Special Issue entitled Cellular functions of glutath …
BACKGROUND: Glutathione (GSH) and related enzymes are critical to cell protection from toxins, both endogenous and environment …
Promising influences of zingerone against natural and chemical toxins: A comprehensive and mechanistic review.
Shamsabadi S, Nazer Y, Ghasemi J, Mahzoon E, Baradaran Rahimi V, Ajiboye BO, Askari VR. Shamsabadi S, et al. Toxicon. 2023 Sep;233:107247. doi: 10.1016/j.toxicon.2023.107247. Epub 2023 Aug 9. Toxicon. 2023. PMID: 37562703 Review.
It possesses anti-inflammatory, antioxidant, and anti-apoptotic properties and also exhibits protective effects against radiation, chemicals, biological toxins, and oxidative stress. The current comprehensive literature review was performed in order to assess the th …
It possesses anti-inflammatory, antioxidant, and anti-apoptotic properties and also exhibits protective effects against radiation, chemicals …
Epigallocatechin Gallate and Glutathione Attenuate Aflatoxin B(1)-Induced Acute Liver Injury in Ducklings via Mitochondria-Mediated Apoptosis and the Nrf2 Signalling Pathway.
Wang Y, Wu J, Wang L, Yang P, Liu Z, Rajput SA, Hassan M, Qi D. Wang Y, et al. Toxins (Basel). 2022 Dec 15;14(12):876. doi: 10.3390/toxins14120876. Toxins (Basel). 2022. PMID: 36548773 Free PMC article.
Aflatoxin B(1) (AFB(1)) exists widely in feed and food with severe hazards, posing a serious threat to human and animal health. Epigallocatechin gallate (EGCG) and glutathione (GSH) have been reported as having anti-oxidative and other functions. ...AFB(1) exposure increas …
Aflatoxin B(1) (AFB(1)) exists widely in feed and food with severe hazards, posing a serious threat to human and animal health. Epigallocate …
Advanced Glycation End Products (AGEs), Glutathione and Breast Cancer: Factors, Mechanism and Therapeutic Interventions.
Sharma AK, Sharma VR, Gupta GK, Ashraf GM, Kamal MA. Sharma AK, et al. Curr Drug Metab. 2019;20(1):65-71. doi: 10.2174/1389200219666180912104342. Curr Drug Metab. 2019. PMID: 30207227
RESULTS: Targeting breast cancer with the specific immunoglobulins and with other therapeutic interventions is needed to inhibit the generation of AGEs and manage glutathione expression, thus having strong implications in the management of breast cancer. ...CONCLUSION: Thi …
RESULTS: Targeting breast cancer with the specific immunoglobulins and with other therapeutic interventions is needed to inhibit the generat …
Glutathione metabolism and its role in hepatotoxicity.
DeLeve LD, Kaplowitz N. DeLeve LD, et al. Pharmacol Ther. 1991 Dec;52(3):287-305. doi: 10.1016/0163-7258(91)90029-l. Pharmacol Ther. 1991. PMID: 1820580 Review.
Glutathione (GSH) fulfills several essential functions: Detoxification of free radicals and toxic oxygen radicals, thiol-disulfide exchange and storage and transfer of cysteine. ...Glutathione homeostasis is a highly complex process, which is predominantly regulated …
Glutathione (GSH) fulfills several essential functions: Detoxification of free radicals and toxic oxygen radicals, thiol-disulfide ex …
Changes in biosynthesis and metabolism of glutathione upon ochratoxin A stress in Arabidopsis thaliana.
Wang Y, Zhao W, Hao J, Xu W, Luo Y, Wu W, Yang Z, Liang Z, Huang K. Wang Y, et al. Plant Physiol Biochem. 2014 Jun;79:10-8. doi: 10.1016/j.plaphy.2014.03.001. Epub 2014 Mar 12. Plant Physiol Biochem. 2014. PMID: 24662377
OTA stimulated a defense response through enhancing glutathione-S-transferase, glutathione peroxidase, glutathione reductase activities, and the transcript levels of these enzymes were increased to maintain the total glutathione content. ...The depleti …
OTA stimulated a defense response through enhancing glutathione-S-transferase, glutathione peroxidase, glutathione redu …
Neutrophil- and glutathione-mediated hepatotoxicity of alpha-naphthylisothiocyanate.
Roth RA, Dahm LJ. Roth RA, et al. Drug Metab Rev. 1997 Feb-May;29(1-2):153-65. doi: 10.3109/03602539709037578. Drug Metab Rev. 1997. PMID: 9187516 Review.
In summary, both glutathione and blood neutrophils contribute to ANIT hepatotoxicity. Glutathione contributes by virtue of its ability to form a reversible S-conjugate with ANIT that is critical in shuttling ANIT into bile. ...
In summary, both glutathione and blood neutrophils contribute to ANIT hepatotoxicity. Glutathione contributes by virtue of its …
Toxicity and detoxification of T-2 toxin in poultry.
Li SJ, Zhang G, Xue B, Ding Q, Han L, Huang JC, Wu F, Li C, Yang C. Li SJ, et al. Food Chem Toxicol. 2022 Nov;169:113392. doi: 10.1016/j.fct.2022.113392. Epub 2022 Aug 28. Food Chem Toxicol. 2022. PMID: 36044934 Review.
., resulting in pathological changes and impaired physiological functions of these organs. Glutathione redox system, superoxide dismutase, catalase and autophagy are protective mechanisms against oxidative stress and apoptosis, and can compensate the pathological changes a …
., resulting in pathological changes and impaired physiological functions of these organs. Glutathione redox system, superoxide dismu …
5,990 results