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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1952 1
1958 1
1962 1
1963 3
1964 1
1965 3
1966 3
1967 4
1968 4
1969 10
1970 5
1971 14
1972 8
1973 17
1974 12
1975 16
1976 28
1977 25
1978 15
1979 8
1980 15
1981 18
1982 27
1983 35
1984 60
1985 46
1986 55
1987 62
1988 61
1989 78
1990 86
1991 96
1992 123
1993 224
1994 253
1995 353
1996 373
1997 376
1998 343
1999 360
2000 408
2001 493
2002 493
2003 483
2004 572
2005 636
2006 496
2007 510
2008 533
2009 537
2010 567
2011 592
2012 635
2013 700
2014 604
2015 585
2016 576
2017 553
2018 494
2019 475
2020 522
2021 481
2022 376
2023 344
2024 178

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14,456 results

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Page 1
Glutathione metabolism and its implications for health.
Wu G, Fang YZ, Yang S, Lupton JR, Turner ND. Wu G, et al. J Nutr. 2004 Mar;134(3):489-92. doi: 10.1093/jn/134.3.489. J Nutr. 2004. PMID: 14988435 Free article. Review.
Glutathione (gamma-glutamyl-cysteinyl-glycine; GSH) is the most abundant low-molecular-weight thiol, and GSH/glutathione disulfide is the major redox couple in animal cells. ...In addition, enteral or parenteral cystine, methionine, N-acetyl-cysteine, and L-2-oxothi …
Glutathione (gamma-glutamyl-cysteinyl-glycine; GSH) is the most abundant low-molecular-weight thiol, and GSH/glutathione disul …
Modulation of neuronal glutathione synthesis by EAAC1 and its interacting protein GTRAP3-18.
Aoyama K, Watabe M, Nakaki T. Aoyama K, et al. Amino Acids. 2012 Jan;42(1):163-9. doi: 10.1007/s00726-011-0861-y. Epub 2011 Mar 5. Amino Acids. 2012. PMID: 21373771 Review.
Glutathione (GSH) plays essential roles in different processes such as antioxidant defenses, cell signaling, cell proliferation, and apoptosis in the central nervous system. ...Here, we focused on the interaction between EAAC1 and GTRAP3-18 at the plasma membrane to invest …
Glutathione (GSH) plays essential roles in different processes such as antioxidant defenses, cell signaling, cell proliferation, and …
An increased need for dietary cysteine in support of glutathione synthesis may underlie the increased risk for mortality associated with low protein intake in the elderly.
McCarty MF, DiNicolantonio JJ. McCarty MF, et al. Age (Dordr). 2015 Oct;37(5):96. doi: 10.1007/s11357-015-9823-8. Epub 2015 Sep 11. Age (Dordr). 2015. PMID: 26362762 Free PMC article. Review.
Aside from its potential pro-anabolic impact, higher dietary protein intakes may protect the elderly in another way-by providing increased amino acid substrate for synthesis of key protective factors. There is growing evidence, in both rodents and humans, that gl …
Aside from its potential pro-anabolic impact, higher dietary protein intakes may protect the elderly in another way-by providing incr …
Glutathione Supplementation of Parenteral Nutrition Prevents Oxidative Stress and Sustains Protein Synthesis in Guinea Pig Model.
Morin G, Guiraut C, Perez Marcogliese M, Mohamed I, Lavoie JC. Morin G, et al. Nutrients. 2019 Sep 3;11(9):2063. doi: 10.3390/nu11092063. Nutrients. 2019. PMID: 31484318 Free PMC article.

We hypothesize that glutathione supplementation in PN can be used as a pro-cysteine that improves glutathione levels and protein synthesis and reduces oxidative stress caused by PN. ...Data were analysed by ANOVA; p < 0.05 was considered significant

…
We hypothesize that glutathione supplementation in PN can be used as a pro-cysteine that improves glutathione levels and pr …
N-acetylcysteine stimulates protein synthesis in enterocytes independently of glutathione synthesis.
Yi D, Hou Y, Wang L, Long M, Hu S, Mei H, Yan L, Hu CA, Wu G. Yi D, et al. Amino Acids. 2016 Feb;48(2):523-33. doi: 10.1007/s00726-015-2105-z. Epub 2015 Oct 3. Amino Acids. 2016. PMID: 26433892
According to previous reports, NAC was thought to exert its effect through glutathione synthesis. This study tested the hypothesis that NAC enhances enterocyte growth and protein synthesis independently of cellular glutathione synthesis. …
According to previous reports, NAC was thought to exert its effect through glutathione synthesis. This study tested the hypoth …
Dietary thiols accelerate aging of C. elegans.
Gusarov I, Shamovsky I, Pani B, Gautier L, Eremina S, Katkova-Zhukotskaya O, Mironov A, Makarov AА, Nudler E. Gusarov I, et al. Nat Commun. 2021 Jul 15;12(1):4336. doi: 10.1038/s41467-021-24634-3. Nat Commun. 2021. PMID: 34267196 Free PMC article.
In contrast, limiting the consumption of dietary thiols, including those naturally derived from the microbiota, extended lifespan. Pharmacological GSH restriction activates the unfolded protein response and increases proteotoxic stress resistance in worms and human cells. …
In contrast, limiting the consumption of dietary thiols, including those naturally derived from the microbiota, extended lifespan. Pharmacol …
SMURF2 predisposes cancer cell toward ferroptosis in GPX4-independent manners by promoting GSTP1 degradation.
Zhang W, Dai J, Hou G, Liu H, Zheng S, Wang X, Lin Q, Zhang Y, Lu M, Gong Y, Xiang Z, Yu Y, Hu Y. Zhang W, et al. Mol Cell. 2023 Dec 7;83(23):4352-4369.e8. doi: 10.1016/j.molcel.2023.10.042. Epub 2023 Nov 27. Mol Cell. 2023. PMID: 38016474
Ferroptosis is a non-apoptotic form of regulated cell death. Glutathione (GSH) peroxidase 4 (GPX4) and GSH-independent ferroptosis suppressor protein 1 (FSP1) have been identified as major defenses. ...
Ferroptosis is a non-apoptotic form of regulated cell death. Glutathione (GSH) peroxidase 4 (GPX4) and GSH-independent ferroptosis su …
Preface.
Makowski GS. Makowski GS. Adv Clin Chem. 2018;87:xiii-xiv. doi: 10.1016/S0065-2423(18)30065-9. Adv Clin Chem. 2018. PMID: 30342714 No abstract available.
Effect of diethylmaleate and other glutathione depletors on protein synthesis.
Costa LG, Murphy SD. Costa LG, et al. Biochem Pharmacol. 1986 Oct 1;35(19):3383-8. doi: 10.1016/0006-2952(86)90439-9. Biochem Pharmacol. 1986. PMID: 3768026
Protein synthesis was measured as the incorporation of [3H]valine into trichloroacetic acid-precipitable material. ...Phorone decreased GSH in liver and brain; however, it had no effect on protein synthesis. BSO decreased GSH levels in liver and kidney …
Protein synthesis was measured as the incorporation of [3H]valine into trichloroacetic acid-precipitable material. ...Phorone …
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