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Standardized Extract (HemoHIM) Protects against Scopolamine-Induced Amnesia in a Murine Model.
Kim SK, Kwon DA, Kim YS, Lee HS, Kim HK, Kim WK. Kim SK, et al. Evid Based Complement Alternat Med. 2021 Mar 17;2021:8884243. doi: 10.1155/2021/8884243. eCollection 2021. Evid Based Complement Alternat Med. 2021. PMID: 33815562 Free PMC article.
In addition, ChAT, mAchR, and CREB mRNA levels were increased in the hippocampus compared with the scopolamine group. Furthermore, HemoHIM treatment resulted in elevated BDNF protein expression. These results indicate that HemoHIM may exert antiamnesic activity by i …
In addition, ChAT, mAchR, and CREB mRNA levels were increased in the hippocampus compared with the scopolamine group. Furthermore, HemoHI …
Antioxidant and Anti-Fatigue Effects of a Standardized Botanical Extract Fraction (HemoHIM) in Forced-Exercised Aged Mice.
Kwon DA, Bak SB, Kim YS, Kim SK, Lee HS. Kwon DA, et al. J Med Food. 2024 Jun;27(6):502-509. doi: 10.1089/jmf.2023.K.0234. Epub 2024 Apr 25. J Med Food. 2024. PMID: 38669056
This study aimed to research the potential antioxidant effects of HemoHIM and its capacity for reducing fatigue in aged mice subjected to forced exercise. After administering HemoHIM 125 (500 mg/kg orally) for 4 weeks in 8-month-old female C57BL/6 mice (4 groups of …
This study aimed to research the potential antioxidant effects of HemoHIM and its capacity for reducing fatigue in aged mice subjecte …
HemoHIM, a herbal preparation, alleviates airway inflammation caused by cigarette smoke and lipopolysaccharide.
Shin NR, Kim SH, Ko JW, Park SH, Lee IC, Ryu JM, Kim JC, Shin IS. Shin NR, et al. Lab Anim Res. 2017 Mar;33(1):40-47. doi: 10.5625/lar.2017.33.1.40. Epub 2017 Mar 27. Lab Anim Res. 2017. PMID: 28400838 Free PMC article.
HemoHIM, herbal preparation has designed for immune system recovery. We investigated the anti-inflammatory effect of HemoHIM on cigarette smoke (CS) and lipopolysaccharide (LPS) induced chronic obstructive pulmonary disease (COPD) mouse model. ...Therefore, we sugge …
HemoHIM, herbal preparation has designed for immune system recovery. We investigated the anti-inflammatory effect of HemoHIM o …
HemoHIM enhances the therapeutic efficacy of ionizing radiation treatment in tumor-bearing mice.
Park HR, Ju EJ, Jo SK, Jung U, Kim SH. Park HR, et al. J Med Food. 2010 Feb;13(1):47-53. doi: 10.1089/jmf.2009.1049. J Med Food. 2010. PMID: 20136435
In addition, HemoHIM administration increased the interleukin-2 and tumor necrosis factor-alpha secretion from lymphocytes stimulated with concanavalin A, which seemed to contribute to the enhanced efficacy of HemoHIM in tumor-bearing mice treated with IR. In conclu …
In addition, HemoHIM administration increased the interleukin-2 and tumor necrosis factor-alpha secretion from lymphocytes stimulated …
Preventive Effect of the Herbal Preparation, HemoHIM, on Cisplatin-Induced Immune Suppression.
Kim SK, Kwon DA, Lee HS, Kim HK, Kim WK. Kim SK, et al. Evid Based Complement Alternat Med. 2019 Mar 20;2019:3494806. doi: 10.1155/2019/3494806. eCollection 2019. Evid Based Complement Alternat Med. 2019. PMID: 31015850 Free PMC article.
We determined the functional effect of the herbal preparation, HemoHIM, on the immune system, by examining the immunomodulatory activities of HemoHIM using immunocompromised mice. ...Mice were injected intraperitoneally with cisplatin, an immunosuppressive anticance …
We determined the functional effect of the herbal preparation, HemoHIM, on the immune system, by examining the immunomodulatory activ …
HemoHIM ameliorates the persistent down-regulation of Th1-like immune responses in fractionated gamma-irradiated mice by modulating the IL-12p70-STAT4 signaling pathway.
Park HR, Jo SK, Choi NH, Jung U. Park HR, et al. Radiat Res. 2012 May;177(5):676-84. doi: 10.1667/rr2768.1. Epub 2012 Apr 2. Radiat Res. 2012. PMID: 22439601
HemoHIM also restored the natural killer cell activities without changing the percentage of natural killer cells in irradiated mice. Furthermore, the administration of HemoHIM prevented the reduction in levels of interleukin-12p70 in irradiated mice. Finally, we fou …
HemoHIM also restored the natural killer cell activities without changing the percentage of natural killer cells in irradiated mice. …
HemoHIM improves ovarian morphology and decreases expression of nerve growth factor in rats with steroid-induced polycystic ovaries.
Kim SH, Lee HJ, Kim JS, Moon C, Kim JC, Bae CS, Park HR, Jung U, Jo SK. Kim SH, et al. J Med Food. 2009 Dec;12(6):1348-52. doi: 10.1089/jmf.2008.1323. J Med Food. 2009. PMID: 20041792
Ovarian morphology was almost normalized, and NGF was normalized in the PCO + HemoHIM group. HemoHIM lowered the high numbers of antral follicles and increased the number of corpora lutea in PCOs. The results are consistent with a beneficial effect of HemoHIM …
Ovarian morphology was almost normalized, and NGF was normalized in the PCO + HemoHIM group. HemoHIM lowered the high numbers …
Protective effects of HemoHIM on immune and hematopoietic systems against gamma-irradiation.
Park HR, Jo SK, Jung U, Yee ST, Kim SH. Park HR, et al. Phytother Res. 2014 Feb;28(2):245-51. doi: 10.1002/ptr.4982. Epub 2013 Apr 18. Phytother Res. 2014. PMID: 23595637
The HemoHIM administration decreased the apoptosis of bone marrow cells in irradiated mice. On the other hand, HemoHIM increased the formation of endogenous spleen colony in irradiated mice. In irradiated mice, the recovery of total leukocytes in the peripheral bloo …
The HemoHIM administration decreased the apoptosis of bone marrow cells in irradiated mice. On the other hand, HemoHIM increas …
Herbal preparation (HemoHIM) enhanced functional maturation of bone marrow-derived dendritic cells mediated toll-like receptor 4.
Lee SJ, Kim JJ, Kang KY, Hwang YH, Jeong GY, Jo SK, Jung U, Park HR, Yee ST. Lee SJ, et al. BMC Complement Altern Med. 2016 Feb 19;16:67. doi: 10.1186/s12906-016-1045-9. BMC Complement Altern Med. 2016. PMID: 26891999 Free PMC article.
The expression of co-stimulatory molecules (CD40, CD80, CD86, MHC I, and MHC II) and the production of cytokines (IL-1beta, IL-6, IL-12p70, and TNF-alpha) were increased by HemoHIM in BMDCs. Furthermore, the antigen-uptake ability of BMDCs was decreased by HemoHIM, …
The expression of co-stimulatory molecules (CD40, CD80, CD86, MHC I, and MHC II) and the production of cytokines (IL-1beta, IL-6, IL-12p70, …
23 results

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