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Year Number of Results
1976 1
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1988 4
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1990 3
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1992 7
1993 6
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2005 142
2006 170
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2008 130
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2,536 results

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Page 1
Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.
van Meurs JB, Pare G, Schwartz SM, Hazra A, Tanaka T, Vermeulen SH, Cotlarciuc I, Yuan X, Mälarstig A, Bandinelli S, Bis JC, Blom H, Brown MJ, Chen C, Chen YD, Clarke RJ, Dehghan A, Erdmann J, Ferrucci L, Hamsten A, Hofman A, Hunter DJ, Goel A, Johnson AD, Kathiresan S, Kampman E, Kiel DP, Kiemeney LA, Chambers JC, Kraft P, Lindemans J, McKnight B, Nelson CP, O'Donnell CJ, Psaty BM, Ridker PM, Rivadeneira F, Rose LM, Seedorf U, Siscovick DS, Schunkert H, Selhub J, Ueland PM, Vollenweider P, Waeber G, Waterworth DM, Watkins H, Witteman JC, den Heijer M, Jacques P, Uitterlinden AG, Kooner JS, Rader DJ, Reilly MP, Mooser V, Chasman DI, Samani NJ, Ahmadi KR. van Meurs JB, et al. Am J Clin Nutr. 2013 Sep;98(3):668-76. doi: 10.3945/ajcn.112.044545. Epub 2013 Jul 3. Am J Clin Nutr. 2013. PMID: 23824729 Free PMC article.
BACKGROUND: The strong observational association between total homocysteine (tHcy) concentrations and risk of coronary artery disease (CAD) and the null associations in the homocysteine-lowering trials have prompted the need to identify genetic …
BACKGROUND: The strong observational association between total homocysteine (tHcy) concentrations and risk of coronary arte …
MTHFR and risk of stroke and heart disease in a low-folate population: a prospective study of 156 000 Chinese adults.
Bennett DA, Parish S, Millwood IY, Guo Y, Chen Y, Turnbull I, Yang L, Lv J, Yu C, Davey Smith G, Wang Y, Wang Y, Peto R, Collins R, Walters RG, Li L, Chen Z, Clarke R; China Kadoorie Biobank (CKB) Study Collaborative Group. Bennett DA, et al. Int J Epidemiol. 2023 Dec 25;52(6):1862-1869. doi: 10.1093/ije/dyad147. Int J Epidemiol. 2023. PMID: 37898918 Free PMC article.
Genetic studies of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism, which increases plasma homocysteine (tHcy) levels, could clarify the causal relevance of elevated tHcy levels for stroke, ischaemic heart disease (IHD) and other dis …
Genetic studies of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism, which increases plasma homocysteine (tHcy) lev …
Homocysteine-reducing B vitamins and ischemic heart disease: a separate-sample Mendelian randomization analysis.
Zhao JV, Schooling CM. Zhao JV, et al. Eur J Clin Nutr. 2017 Feb;71(2):267-273. doi: 10.1038/ejcn.2016.246. Epub 2016 Nov 30. Eur J Clin Nutr. 2017. PMID: 27901035
BACKGROUND/OBJECTIVES: Observationally, homocysteine is positively associated with ischemic heart disease (IHD) and unhealthy lipids; folate and vitamin B12, which reduce homocysteine, are associated with lower IHD risk and healthy lipids. ...To …
BACKGROUND/OBJECTIVES: Observationally, homocysteine is positively associated with ischemic heart disease (IHD) …
Homocysteine and cardiovascular disease.
Refsum H, Ueland PM, Nygård O, Vollset SE. Refsum H, et al. Annu Rev Med. 1998;49:31-62. doi: 10.1146/annurev.med.49.1.31. Annu Rev Med. 1998. PMID: 9509248 Review.
An elevated level of total homocysteine (tHcy) in blood, denoted hyperhomocysteinemia, is emerging as a prevalent and strong risk factor for atherosclerotic vascular disease in the coronary, cerebral, and peripheral vessels, and for arterial and venous thromb …
An elevated level of total homocysteine (tHcy) in blood, denoted hyperhomocysteinemia, is emerging as a prevalent and strong risk fac …
Homocysteine in the prevention of ischemic heart disease, stroke and venous thromboembolism: therapeutic target or just another distraction?
Lonn E. Lonn E. Curr Opin Hematol. 2007 Sep;14(5):481-7. doi: 10.1097/MOH.0b013e3282c48bd8. Curr Opin Hematol. 2007. PMID: 17934354 Review.
PURPOSE OF REVIEW: Homocysteine has been proposed as a potentially modifiable risk factor for arterial and venous vascular disease. ...RECENT FINDINGS: The current review briefly summarizes observational studies with emphasis on new meta-analyses linking homocyst …
PURPOSE OF REVIEW: Homocysteine has been proposed as a potentially modifiable risk factor for arterial and venous vascular disease …
Lipids, risk factors and ischaemic heart disease.
Castelli WP. Castelli WP. Atherosclerosis. 1996 Jul;124 Suppl:S1-9. doi: 10.1016/0021-9150(96)05851-0. Atherosclerosis. 1996. PMID: 8831910 Review.
In addition, many other factors including diabetes, haemostatic factors such as fibrinogen, factor VII, plasminogen activator inhibitors, and new factors such as apolipoprotein E4 and homocysteine, are known to increase the risk of developing clinical CVD. ...Once identifi …
In addition, many other factors including diabetes, haemostatic factors such as fibrinogen, factor VII, plasminogen activator inhibitors, an …
Clinical value and expression of Homer 1, homocysteine, S-adenosyl-l-homocysteine, fibroblast growth factors 23 in coronary heart disease.
Zhang Z, Wang L, Zhan Y, Xie C, Xiang Y, Chen D, Wu Y. Zhang Z, et al. BMC Cardiovasc Disord. 2022 May 12;22(1):215. doi: 10.1186/s12872-022-02554-4. BMC Cardiovasc Disord. 2022. PMID: 35546659 Free PMC article.
BACKGROUND: This study aimed to explore clinical value and expression of Homer 1, S-adenosyl-l-homocysteine (SAH), homocysteine (Hcy), fibroblast growth factors (FGF) 23 in coronary heart disease (CHD). ...The degree of coronary artery …
BACKGROUND: This study aimed to explore clinical value and expression of Homer 1, S-adenosyl-l-homocysteine (SAH), homocysteine …
Reconciling the evidence on serum homocysteine and ischaemic heart disease: a meta-analysis.
Wald DS, Morris JK, Wald NJ. Wald DS, et al. PLoS One. 2011 Feb 2;6(2):e16473. doi: 10.1371/journal.pone.0016473. PLoS One. 2011. PMID: 21311765 Free PMC article.
BACKGROUND: Results from genetic epidemiological studies suggest that raised serum homocysteine is a cause of ischaemic heart disease, but the results of randomised trials suggest otherwise. ...Meta-analysis of the MTHFR studies showed a statistically …
BACKGROUND: Results from genetic epidemiological studies suggest that raised serum homocysteine is a cause of ischaemic hea …
Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis.
Homocysteine Studies Collaboration. Homocysteine Studies Collaboration. JAMA. 2002 Oct 23-30;288(16):2015-22. doi: 10.1001/jama.288.16.2015. JAMA. 2002. PMID: 12387654
CONTEXT: It has been suggested that total blood homocysteine concentrations are associated with the risk of ischemic heart disease (IHD) and stroke. ...Studies of the impact on disease risk of genetic variants that affect blood homocysteine …
CONTEXT: It has been suggested that total blood homocysteine concentrations are associated with the risk of ischemic heart …
[Homoarginine level and methionine-homocysteine balance in patients with ischemic heart disease.].
Zhloba AA, Subbotina TF, Molchan NS, Polushin YS. Zhloba AA, et al. Klin Lab Diagn. 2019;64(9):516-524. doi: 10.18821/0869-2084-2019-64-9-516-524. Klin Lab Diagn. 2019. PMID: 31610102 Russian.
Relationships of hArg and other amino acids, including methionine (Met) and total homocysteine (tHcy), and their ratio in patients with ischemic heart disease were evaluated. The study included 74 patients with coronary heart disease …
Relationships of hArg and other amino acids, including methionine (Met) and total homocysteine (tHcy), and their ratio in patients wi …
2,536 results