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154 results

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HTZ-1/H2A.z and MYS-1/MYST HAT act redundantly to maintain cell fates in somatic gonadal cells through repression of ceh-22 in C. elegans.
Shibata Y, Sawa H, Nishiwaki K. Shibata Y, et al. Development. 2014 Jan;141(1):209-18. doi: 10.1242/dev.090746. Development. 2014. PMID: 24346701
BET-1 controlled the subnuclear localization of HTZ-1. HTZ-1 and MYS-1 maintained the fates of the somatic gonadal cells (SGCs) through the repression of a target, ceh-22/Nkx2.5, which induced the formation of the leader cells of the gonad. H3K27 demethylase, UTX-1, …
BET-1 controlled the subnuclear localization of HTZ-1. HTZ-1 and MYS-1 maintained the fates of the somatic gonadal cells (SGCs …
Temporal regulation of foregut development by HTZ-1/H2A.Z and PHA-4/FoxA.
Updike DL, Mango SE. Updike DL, et al. PLoS Genet. 2006 Sep 29;2(9):e161. doi: 10.1371/journal.pgen.0020161. Epub 2006 Aug 11. PLoS Genet. 2006. PMID: 17009877 Free PMC article.
Using a nuclear spot assay to visualize HTZ-1 in living embryos as organogenesis proceeds, we show that HTZ-1 is recruited to foregut promoters at the time of transcriptional onset, and this recruitment requires PHA-4. Loss of htz-1 by RNAi is lethal and lead …
Using a nuclear spot assay to visualize HTZ-1 in living embryos as organogenesis proceeds, we show that HTZ-1 is recruited to …
The genomic distribution and function of histone variant HTZ-1 during C. elegans embryogenesis.
Whittle CM, McClinic KN, Ercan S, Zhang X, Green RD, Kelly WG, Lieb JD. Whittle CM, et al. PLoS Genet. 2008 Sep 12;4(9):e1000187. doi: 10.1371/journal.pgen.1000187. PLoS Genet. 2008. PMID: 18787694 Free PMC article.
The sites of HTZ-1 incorporation during embryogenesis reveal a genome wrought by developmental processes. HTZ-1 is incorporated upstream of 23% of C. elegans genes. While these genes tend to be required for development and occupied by RNA polymerase II, HTZ-1 …
The sites of HTZ-1 incorporation during embryogenesis reveal a genome wrought by developmental processes. HTZ-1 is incorporate …
Regulation of DCC localization by HTZ-1/H2A.Z and DPY-30 does not correlate with H3K4 methylation levels.
Petty E, Laughlin E, Csankovszki G. Petty E, et al. PLoS One. 2011;6(10):e25973. doi: 10.1371/journal.pone.0025973. Epub 2011 Oct 5. PLoS One. 2011. PMID: 21998734 Free PMC article.
We wanted to know whether other chromatin components coordinated with HTZ-1 to regulate DCC localization. One candidate is DPY-30, a protein known to play a role in DCC localization. ...Additionally, loss of H3K4 methylation does not enhance DCC mislocalization in htz
We wanted to know whether other chromatin components coordinated with HTZ-1 to regulate DCC localization. One candidate is DPY-30, a …
Restricting dosage compensation complex binding to the X chromosomes by H2A.Z/HTZ-1.
Petty EL, Collette KS, Cohen AJ, Snyder MJ, Csankovszki G. Petty EL, et al. PLoS Genet. 2009 Oct;5(10):e1000699. doi: 10.1371/journal.pgen.1000699. Epub 2009 Oct 23. PLoS Genet. 2009. PMID: 19851459 Free PMC article.
Using RNAi-based assays, we show that reducing levels of the histone H2A variant, H2A.Z (HTZ-1 in C. elegans), leads to partial disruption of dosage compensation. ...We find that reduction of HTZ-1 levels by RNA interference (RNAi) and mutation results in only a ver …
Using RNAi-based assays, we show that reducing levels of the histone H2A variant, H2A.Z (HTZ-1 in C. elegans), leads to partial disru …
Serum 21-Deoxycortisol for Diagnosis of Nonclassic Congenital Adrenal Hyperplasia in Women With Androgen Excess.
Ng JL, Lim EM, Zhang R, Beilby JP, Watts GF, Brown SJ, Stuckey BGA. Ng JL, et al. J Clin Endocrinol Metab. 2023 Nov 17;108(12):e1560-e1570. doi: 10.1210/clinem/dgad377. J Clin Endocrinol Metab. 2023. PMID: 37358001 Free PMC article.
Measurement of 21-deoxycortisol (21DF) may simplify the diagnosis of heterozygosity (HTZ), the presence of 1 affected CYP21A2 allele, which currently relies on complex molecular studies. OBJECTIVE: We aimed to determine LC-MS/MS-specific criteria for NCCAH and HTZ a …
Measurement of 21-deoxycortisol (21DF) may simplify the diagnosis of heterozygosity (HTZ), the presence of 1 affected CYP21A2 allele, …
Egg White Protein Carrier-Assisted Development of Solid Dispersion for Improved Aqueous Solubility and Permeability of Poorly Water Soluble Hydrochlorothiazide.
Telange DR, Jain SP, Pethe AM, Kharkar PS. Telange DR, et al. AAPS PharmSciTech. 2021 Mar 8;22(3):94. doi: 10.1208/s12249-021-01967-2. AAPS PharmSciTech. 2021. PMID: 33683493
The dissolution study in phosphate buffer media (pH 6.8) revealed that HTZ-EWP SD4 significantly enhanced the release rate of HTZ (~ 87 %) over to HTZ (~ 25 %). The permeation rate of HTZ from optimized HTZ-EWP SD4 was enhanced significantly (~ …
The dissolution study in phosphate buffer media (pH 6.8) revealed that HTZ-EWP SD4 significantly enhanced the release rate of HTZ
Generalizability and Diagnostic Performance of AI Models for Thyroid US.
Xu W, Jia X, Mei Z, Gu X, Lu Y, Fu CC, Zhang R, Gu Y, Chen X, Luo X, Li N, Bai B, Li Q, Yan J, Zhai H, Guan L, Gong B, Zhao K, Fang Q, He C, Zhan W, Luo T, Zhang H, Dong Y, Zhou J; Chinese Artificial Intelligence Alliance for Thyroid and Breast Ultrasound. Xu W, et al. Radiology. 2023 Jun;307(5):e221157. doi: 10.1148/radiol.221157. Radiology. 2023. PMID: 37338356
Systemic evaluation of novel acaricide hexythiazox for bioactivity improvement and risk reduction at the enantiomer level.
Zhang P, Yang F, Ran L, Yang C, Tang C, Ke X, Chen J, Xiao W, He L, Xu Z. Zhang P, et al. Sci Total Environ. 2024 May 20;926:171907. doi: 10.1016/j.scitotenv.2024.171907. Epub 2024 Mar 22. Sci Total Environ. 2024. PMID: 38522548
Molecular docking indicated greater interactions between (4R, 5R)-(+)-HTZ and chitin synthase leading to higher bioactivity of (4R, 5R)-(+)-HTZ. ...These findings suggest that earthworms exhibited enantiomer-specific responses to (4R, 5R)-(+)-HTZ and (4S, 5S) …
Molecular docking indicated greater interactions between (4R, 5R)-(+)-HTZ and chitin synthase leading to higher bioactivity of (4R, 5 …
Lipoprotein apheresis: state of the art and novelties.
Stefanutti C, Julius U. Stefanutti C, et al. Atheroscler Suppl. 2013 Jan;14(1):19-27. doi: 10.1016/j.atherosclerosissup.2012.10.021. Atheroscler Suppl. 2013. PMID: 23357136 Review.
A therapy based solely on current available drugs does not achieve the desired results in the Hoz- and DHtz forms of FH or in approximately 10-20% of the Htz form. For the aforementioned clinical conditions, LA treatment offers a necessary therapeutic approach. ...Clinical …
A therapy based solely on current available drugs does not achieve the desired results in the Hoz- and DHtz forms of FH or in approximately …
154 results