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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1953 1
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1967 12
1968 6
1969 7
1970 7
1971 20
1972 32
1973 30
1974 24
1975 28
1976 30
1977 29
1978 25
1979 25
1980 24
1981 29
1982 23
1983 23
1984 33
1985 35
1986 28
1987 35
1988 28
1989 26
1990 17
1991 32
1992 26
1993 19
1994 36
1995 32
1996 25
1997 27
1998 31
1999 30
2000 36
2001 33
2002 33
2003 41
2004 43
2005 35
2006 40
2007 36
2008 41
2009 44
2010 52
2011 40
2012 49
2013 50
2014 43
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2023 48
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1,898 results

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Page 1
Lysine Hydroxylation and Cross-Linking of Collagen.
Yamauchi M, Terajima M, Shiiba M. Yamauchi M, et al. Methods Mol Biol. 2019;1934:309-324. doi: 10.1007/978-1-4939-9055-9_19. Methods Mol Biol. 2019. PMID: 31256387
Collagens represent a large family of structurally related proteins containing a unique triple-helical structure. ...This chapter presents an overview of lysine hydroxylation and cross-linking of collagen, and the analytical methods we have developed....
Collagens represent a large family of structurally related proteins containing a unique triple-helical structure. ...This chapter pre …
Recombinant expression of hydroxylated human collagen in Escherichia coli.
Rutschmann C, Baumann S, Cabalzar J, Luther KB, Hennet T. Rutschmann C, et al. Appl Microbiol Biotechnol. 2014 May;98(10):4445-55. doi: 10.1007/s00253-013-5447-z. Epub 2013 Dec 21. Appl Microbiol Biotechnol. 2014. PMID: 24362857 Free article.
The respective levels of prolyl and lysyl hydroxylation reaching 25 % and 26 % were similar to the hydroxylation levels of native human collagen type III. ...The triple helix signature of recombinant hydroxylated collagen was confirmed by circul …
The respective levels of prolyl and lysyl hydroxylation reaching 25 % and 26 % were similar to the hydroxylation levels of nat …
Contrasting Local and Macroscopic Effects of Collagen Hydroxylation.
Varma S, Orgel JPRO, Schieber JD. Varma S, et al. Int J Mol Sci. 2021 Aug 23;22(16):9068. doi: 10.3390/ijms22169068. Int J Mol Sci. 2021. PMID: 34445791 Free PMC article.
Collagen is heavily hydroxylated. Experiments show that proline hydroxylation is important to triple helix (monomer) stability, fibril assembly, and interaction of fibrils with other molecules. ...Our simulations reproduce the experimental observation that …
Collagen is heavily hydroxylated. Experiments show that proline hydroxylation is important to triple helix (monomer) st …
Collagen type II-hyaluronan interactions - the effect of proline hydroxylation: a molecular dynamics study.
Bełdowski P, Przybyłek M, Bełdowski D, Dedinaite A, Sionkowska A, Cysewski P, Claesson PM. Bełdowski P, et al. J Mater Chem B. 2022 Nov 30;10(46):9713-9723. doi: 10.1039/d2tb01550a. J Mater Chem B. 2022. PMID: 36413305
This article presents the results from molecular dynamics calculations of HA-collagen type II interactions with hyaluronan. The applied protocol employed docking and geometry optimization of complexes built using collagen structures with different numbers of hydr …
This article presents the results from molecular dynamics calculations of HA-collagen type II interactions with hyaluronan. The appli …
Investigation of Triple-Helix Collagen Hydroxylation by Solid-State NMR Spectroscopy.
Chow WY. Chow WY. Methods Mol Biol. 2019;1944:57-77. doi: 10.1007/978-1-4939-9095-5_5. Methods Mol Biol. 2019. PMID: 30840235
Solid-state nuclear magnetic resonance spectroscopy (ssNMR) is an emerging technique in structural methods of studying collagen proteins, capable of identifying features on an atomic length scale in tissues and protein samples without extensive extraction or purification. …
Solid-state nuclear magnetic resonance spectroscopy (ssNMR) is an emerging technique in structural methods of studying collagen prote …
Components of the collagen prolyl 3-hydroxylation complex are crucial for normal bone development.
Marini JC, Cabral WA, Barnes AM, Chang W. Marini JC, et al. Cell Cycle. 2007 Jul 15;6(14):1675-81. doi: 10.4161/cc.6.14.4474. Epub 2007 May 18. Cell Cycle. 2007. PMID: 17630507 Review.
Prolyl 3-hydroxylase 1 (P3H1), cartilage-associated protein (CRTAP) and cyclophilin B (CyPB) form a complex in the endoplasmic reticulum which is responsible for 3-hydroxylation of a limited number of proline residues in types I, II and V collagens. In this complex, …
Prolyl 3-hydroxylase 1 (P3H1), cartilage-associated protein (CRTAP) and cyclophilin B (CyPB) form a complex in the endoplasmic reticulum whi …
Developmental growth plate cartilage formation suppressed by artificial light at night via inhibiting BMAL1-driven collagen hydroxylation.
Chen G, Tang Q, Yu S, Shen Y, Sun J, Peng J, Yin Y, Feng G, Lu X, Mei G, Zhang Y, Wan Q, Zhang L, Chen L. Chen G, et al. Cell Death Differ. 2023 Jun;30(6):1503-1516. doi: 10.1038/s41418-023-01152-x. Epub 2023 Apr 7. Cell Death Differ. 2023. PMID: 37029304
Excessive LAN exposure induces downregulation of the core circadian clock protein BMAL1, which leads to collagen accumulation in the ER. Further investigations suggest that BMAL1 is the direct transcriptional activator of prolyl 4-hydroxylase subunit alpha 1 (P4ha1) in cho …
Excessive LAN exposure induces downregulation of the core circadian clock protein BMAL1, which leads to collagen accumulation in the …
Role of prolyl hydroxylation in the molecular interactions of collagens.
Rappu P, Salo AM, Myllyharju J, Heino J. Rappu P, et al. Essays Biochem. 2019 Sep 13;63(3):325-335. doi: 10.1042/EBC20180053. Print 2019 Sep 13. Essays Biochem. 2019. PMID: 31350381 Free PMC article. Review.
Co- and post-translational hydroxylation of proline residues is critical for the stability of the triple helical collagen structure. In this review, we summarise the biology of collagen prolyl 4-hydroxylases and collagen prolyl 3-hydroxylases, the enzy …
Co- and post-translational hydroxylation of proline residues is critical for the stability of the triple helical collagen stru …
Ascorbate requirement for hydroxylation and secretion of procollagen: relationship to inhibition of collagen synthesis in scurvy.
Peterkofsky B. Peterkofsky B. Am J Clin Nutr. 1991 Dec;54(6 Suppl):1135S-1140S. doi: 10.1093/ajcn/54.6.1135s. Am J Clin Nutr. 1991. PMID: 1720597 Review.
Vitamin C deficiency is associated with defective connective tissue, particularly in wound healing. Ascorbate is required for hydroxylation of proline residues in procollagen and hydroxyproline stabilizes the collagen triple helical structure. Consequently, ascorbat …
Vitamin C deficiency is associated with defective connective tissue, particularly in wound healing. Ascorbate is required for hydroxylati …
Differential effects of collagen prolyl 3-hydroxylation on skeletal tissues.
Homan EP, Lietman C, Grafe I, Lennington J, Morello R, Napierala D, Jiang MM, Munivez EM, Dawson B, Bertin TK, Chen Y, Lua R, Lichtarge O, Hicks J, Weis MA, Eyre D, Lee BH. Homan EP, et al. PLoS Genet. 2014 Jan;10(1):e1004121. doi: 10.1371/journal.pgen.1004121. Epub 2014 Jan 23. PLoS Genet. 2014. PMID: 24465224 Free PMC article.
Recent data suggest that prolyl 3-hydroxylation of Pro986 is not required for the structural stability of collagen; however, the absence of this post-translational modification may disrupt protein-protein interactions integral for proper collagen folding and …
Recent data suggest that prolyl 3-hydroxylation of Pro986 is not required for the structural stability of collagen; however, t …
1,898 results