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Retinoid stability and degradation kinetics in commercial cosmetic products.
Temova Rakuša Ž, Škufca P, Kristl A, Roškar R. Temova Rakuša Ž, et al. J Cosmet Dermatol. 2021 Jul;20(7):2350-2358. doi: 10.1111/jocd.13852. Epub 2020 Dec 2. J Cosmet Dermatol. 2021. PMID: 33206444
METHODS: A validated HPLC-UV methodology was utilized for determination of the most common retinoids in cosmetics (retinol, retinyl palmitate, beta-carotene) and a newer promising retinoid (hydroxypinacolone retinoate). The stability of 16 retinoid derivatives in 12 …
METHODS: A validated HPLC-UV methodology was utilized for determination of the most common retinoids in cosmetics (retinol, retinyl palmitat …
The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging.
Wang Q, Hu F, Hu X, Xie Y, Du L, Ye R. Wang Q, et al. J Cosmet Dermatol. 2023 Jul;22(7):2040-2049. doi: 10.1111/jocd.15662. Epub 2023 Feb 10. J Cosmet Dermatol. 2023. PMID: 36762391
OBJECTIVE: In this study, we aimed to determine the optimal ratio of two retinol derivatives-hydroxypinacolone retinoate (HPR) and retinyl propionate (RP) in terms of dermal remodeling and skin aging prevention-and to investigate their synergistic antiaging effects …
OBJECTIVE: In this study, we aimed to determine the optimal ratio of two retinol derivatives-hydroxypinacolone retinoate (HPR) …
High Stability and Low Irritation of Retinol Propionate and Hydroxypinacolone Retinoate Supramolecular Nanoparticles with Effective Anti-Wrinkle Efficacy.
Bai D, Hu F, Xu H, Huang J, Wu C, Zhang J, Ye R. Bai D, et al. Pharmaceutics. 2023 Feb 22;15(3):731. doi: 10.3390/pharmaceutics15030731. Pharmaceutics. 2023. PMID: 36986592 Free PMC article.
Gravi-A nanoparticles, composed of retinyl propionate (RP) and hydroxypinacolone retinoate (HPR), were prepared by encapsulating the two using the high-pressure homogenization technique. ...
Gravi-A nanoparticles, composed of retinyl propionate (RP) and hydroxypinacolone retinoate (HPR), were prepared by encapsulati …
Efficacy and safety of a new topical gel formulation containing retinol encapsulated in glycospheres and hydroxypinacolone retinoate, an antimicrobial peptide, salicylic acid, glycolic acid and niacinamide for the treatment of mild acne: preliminary results of a 2-month prospective study.
Villani A, Annunziata MC, Cinelli E, Donnarumma M, Milani M, Fabbrocini G. Villani A, et al. G Ital Dermatol Venereol. 2020 Oct;155(5):676-679. doi: 10.23736/S0392-0488.20.06581-5. Epub 2020 Sep 1. G Ital Dermatol Venereol. 2020. PMID: 32869963
The aim of this study was to evaluate the efficacy and tolerability of a new topical gel formulation that combines retinol encapsulated in glycospheres and hydroxypinacolone retinoate, associated with an anti-microbial peptide (BIOPEP-15) salicylic acid, glycolic ac …
The aim of this study was to evaluate the efficacy and tolerability of a new topical gel formulation that combines retinol encapsulated in g …
Efficacy and safety of a 12-month treatment with a combination of hydroxypinacolone retinoate and retinol glycospheres as maintenance therapy in acne patients after oral isotretinoin.
Bettoli V, Zauli S, Borghi A, Toni G, Ricci M, Bertoldi AM, Virgili A. Bettoli V, et al. G Ital Dermatol Venereol. 2017 Feb;152(1):13-17. doi: 10.23736/S0392-0488.16.05201-9. Epub 2016 Feb 18. G Ital Dermatol Venereol. 2017. PMID: 26889724 Clinical Trial.
The aim of this study is to investigate efficacy and safety of a 12-month maintenance treatment with a product, based on Retinsphere technology that combines retinol encapsulated in glycospheres and hydroxypinacolone retinoate (Biretix gel), to control acne relapse …
The aim of this study is to investigate efficacy and safety of a 12-month maintenance treatment with a product, based on Retinsphere technol …
Quality control of retinoids in commercial cosmetic products.
Temova Rakuša Ž, Škufca P, Kristl A, Roškar R. Temova Rakuša Ž, et al. J Cosmet Dermatol. 2021 Apr;20(4):1166-1175. doi: 10.1111/jocd.13686. Epub 2020 Sep 16. J Cosmet Dermatol. 2021. PMID: 32813932
However, retinoid concentration in cosmetics is restricted, and one particular form-retinoic acid, is banned in cosmetics due to safety reasons. AIMS: Within this study, we aimed to examine the quality of a considerable number of commercial retinoid cosmetic products in te …
However, retinoid concentration in cosmetics is restricted, and one particular form-retinoic acid, is banned in cosmetics due to safe …
Treatment of mild to moderate acne with a fixed combination of hydroxypinacolone retinoate, retinol glycospheres and papain glycospheres.
Veraldi S, Barbareschi M, Guanziroli E, Bettoli V, Minghetti S, Capitanio B, Sinagra JL, Sedona P, Schianchi R. Veraldi S, et al. G Ital Dermatol Venereol. 2015 Apr;150(2):143-7. G Ital Dermatol Venereol. 2015. PMID: 25876142 Clinical Trial.
AIM: A fixed combination of 0.1% hydroxypinacolone retinoate (synthetic esther of 9-cis-retinoic acid), 1% retinol in glycospheres and 2% papain in glycospheres in aqueous gel has been recently introduced into the Italian market in order to reduce the inciden …
AIM: A fixed combination of 0.1% hydroxypinacolone retinoate (synthetic esther of 9-cis-retinoic acid), 1% retinol in g …
Probiotic supplement combined with topical therapy in the treatment of mild to moderate acne: results from an Italian single centre interventional study.
Marasca C, Ruggiero A, Cacciapuoti S, Fabbrocini G, Annunziata MC. Marasca C, et al. Ital J Dermatol Venerol. 2022 Dec;157(6):510-514. doi: 10.23736/S2784-8671.22.07361-3. Epub 2022 Sep 30. Ital J Dermatol Venerol. 2022. PMID: 36177779 Free article.
The aim of our study was to evaluate the efficacy of a new treatment protocol for acne based on an oral supplement composed of biotin and 3 strains of lactic ferments combined with a topical gel composed of azelaic acid, hydroxypinacolone retinoate, and alpha-hydrox …
The aim of our study was to evaluate the efficacy of a new treatment protocol for acne based on an oral supplement composed of biotin and 3 …
Evaluation of the safety and efficacy of cosmetics ingredient Spherulites Paeony Superior Retinol.
Han J, Gong R, Wang B, Gong T, Chen X. Han J, et al. J Cosmet Dermatol. 2024 Apr 25. doi: 10.1111/jocd.16345. Online ahead of print. J Cosmet Dermatol. 2024. PMID: 38665039
BACKGROUND: Microencapsulation of hydroxypinacolone retinoate (HPR) can improve its application in cosmetics. ...
BACKGROUND: Microencapsulation of hydroxypinacolone retinoate (HPR) can improve its application in cosmetics. ...
Characterization of Acne-Prone Skin with Reflectance Confocal Microscopy and Optical Coherence Tomography and Modifications Induced by Topical Treatment and Probiotic Supplementation.
Manfredini M, Sticchi A, Lippolis N, Pedroni G, Giovani M, Ciardo S, Chello C, Guida S, Farnetani F, Pellacani G. Manfredini M, et al. J Clin Med. 2023 Jul 20;12(14):4787. doi: 10.3390/jcm12144787. J Clin Med. 2023. PMID: 37510902 Free PMC article.
A group of 20 patients received a daily combined treatment over a period of 3 months, consisting of probiotic supplementation with three strains of 10(9) colony-forming units of Lactobacillus (Lactobacillus reuteri, Lactobacillus casei subsp. rhamnosus, Lactobacillus plantarum) a …
A group of 20 patients received a daily combined treatment over a period of 3 months, consisting of probiotic supplementation with three str …
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