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Year Number of Results
1988 1
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1992 2
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1998 4
1999 1
2002 3
2003 3
2004 3
2005 6
2006 10
2007 1
2008 8
2009 13
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2015 8
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231 results

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Page 1
A Miniature Orthogonal Injection Ion Funnel (MO-IF) Providing Enhanced Performance for the Miniature Mass Spectrometer.
Tu M, Xu W, Zhai Y. Tu M, et al. J Am Soc Mass Spectrom. 2024 Apr 29. doi: 10.1021/jasms.4c00100. Online ahead of print. J Am Soc Mass Spectrom. 2024. PMID: 38683544
As a result, a lower limit of detection of 0.5 ng/mL were obtained with good linearity for hypaconitine. Additionally, the MO-IF further decreased the buffer gas pressure in the second vacuum chamber and improved the mass resolution by 1.1-1.5 times at different scan rates …
As a result, a lower limit of detection of 0.5 ng/mL were obtained with good linearity for hypaconitine. Additionally, the MO-IF furt …
Mahuang Fuzi Xixin decoction alleviates allergic rhinitis by inhibiting NLRP3/Caspase-1/GSDMD-N-mediated pyroptosis.
Ding M, Wei X, Liu C, Tan X. Ding M, et al. J Ethnopharmacol. 2024 Jun 12;327:118041. doi: 10.1016/j.jep.2024.118041. Epub 2024 Mar 11. J Ethnopharmacol. 2024. PMID: 38479543
RESULTS: Thirty-three compounds in MFXD were identified, including ephedrine, pseudoephedrine, higenamine, aconine, aconitine, benzoylmesaconitine, benzoylhypaconine and hypaconitine. In the in vivo study, oral taken of MFXD/dexamethasone significantly ameliorated AR sympt …
RESULTS: Thirty-three compounds in MFXD were identified, including ephedrine, pseudoephedrine, higenamine, aconine, aconitine, benzoylmesaco …
Anti-rheumatic potential vis-a-vis aconitine and hypaconitine content analysis in different Aconitum spp. from Sikkim Himalayas (India).
Kumar B, Misra A, Rawat P, Agnihotri P, Srivastava S. Kumar B, et al. Chem Biodivers. 2024 Feb;21(2):e202301656. doi: 10.1002/cbdv.202301656. Epub 2024 Jan 31. Chem Biodivers. 2024. PMID: 38217357
The present study aims to evaluate anti-rheumatic potential in seven Aconitum species and correlation with aconitine and hypaconitine content. Anti-rheumatic potential was analyzed through in vitro xanthine oxidase inhibition, anti-inflammatory and ROS scavenging assays; a …
The present study aims to evaluate anti-rheumatic potential in seven Aconitum species and correlation with aconitine and hypaconitine …
[Differences in chemical components in processing of dried ginger-steamed, sand-fried, and rice swill water-bleached Aconiti Lateralis Radix Praeparata pieces in "Jianchang" faction based on UPLC-MS/MS].
Zhou Y, Zhong LY, Luo HB, Zhong SM, Liu B, Deng Q, Xu FY. Zhou Y, et al. Zhongguo Zhong Yao Za Zhi. 2023 Dec;48(23):6387-6395. doi: 10.19540/j.cnki.cjcmm.20230908.301. Zhongguo Zhong Yao Za Zhi. 2023. PMID: 38211995 Chinese.
Samples were collected during the processing of the three types of ALRP pieces, yielding raw ALRP pieces, water-bleached Yin-FP, ginger juice-moistened Yin-FP, steamed Yin-FP, water-bleached Yang-FP, sand-fried Yang-FP, water-bleached DFP, rice swill water-bleached DFP, and roast …
Samples were collected during the processing of the three types of ALRP pieces, yielding raw ALRP pieces, water-bleached Yin-FP, ginger juic …
Unlocking the hidden potential: Enhancing the utilization of stems and leaves through metabolite analysis and toxicity assessment of various parts of Aconitum carmichaelii.
Zhou Y, Qu C, Yan H, Chu T, Wu J, Kang Q, Peng C, Wang Y, Tan Y. Zhou Y, et al. J Ethnopharmacol. 2024 Apr 6;323:117693. doi: 10.1016/j.jep.2023.117693. Epub 2024 Jan 2. J Ethnopharmacol. 2024. PMID: 38176669
Finally, through correlation analysis and animal experimental verification, mesaconitine, deoxyaconitine, and hypaconitine were used as toxicity markers. CONCLUSION: Given the low toxicity of the stems and leaves and the potential efficacy of aporphine alkaloids, the stems …
Finally, through correlation analysis and animal experimental verification, mesaconitine, deoxyaconitine, and hypaconitine were used …
Comprehensive insight into the pharmacology, pharmacokinetics, toxicity, detoxification and extraction of hypaconitine from Aconitum plants.
Xiang G, Guo S, Qin J, Gao H, Zhang Y, Wang S. Xiang G, et al. J Ethnopharmacol. 2024 Mar 1;321:117505. doi: 10.1016/j.jep.2023.117505. Epub 2023 Nov 26. J Ethnopharmacol. 2024. PMID: 38016573 Review.
ETHNOPHARMACOLOGICAL RELEVANCE: Hypaconitine (HA), a diterpenoid alkaloid, mainly derived from Aconitum plants such as Acoitum carmichaeli Debx. ...The search was performed using specific keywords such as "hypaconitine," "heart failure," "anti-inflammatory," "aconit …
ETHNOPHARMACOLOGICAL RELEVANCE: Hypaconitine (HA), a diterpenoid alkaloid, mainly derived from Aconitum plants such as Acoitum carmic …
Sensitive quantitation of ultra-trace toxic aconitines in complex matrices by perfusion nano-electrospray ionization mass spectrometry combined with gas-liquid microextraction.
Qiu Z, Wei C, Kang L, Zhou L, Lai C, Li X, Yan B, Xu J, Wang S, Huang L. Qiu Z, et al. Talanta. 2024 Mar 1;269:125402. doi: 10.1016/j.talanta.2023.125402. Epub 2023 Nov 11. Talanta. 2024. PMID: 37979510
Further, GLME device was applied to obtain the highly specific enrichment of the target diester alkaloids more than 1000-fold, and accurate absolute quantitation of trace aconitine, mesaconitine, and hypaconitine in the extracts of Heishunpian, Zhichuanwu and Zhicaowu was …
Further, GLME device was applied to obtain the highly specific enrichment of the target diester alkaloids more than 1000-fold, and accurate …
Effect of microneedle roller on promoting transdermal absorption of crossbow-medicine liquid via transdermal administration of Traditional Chinese Medicine and the safety of crossbow-medicine needle therapy: An experimental study.
Luo H, Zan F, Cui J. Luo H, et al. J Ethnopharmacol. 2023 Dec 5;317:116751. doi: 10.1016/j.jep.2023.116751. Epub 2023 Jun 7. J Ethnopharmacol. 2023. PMID: 37295573 Free article.
In-vitro experiment: In the microneedle-roller group and crossbow-medicine liquid application group, the effect of transdermal delivery was identified in all the four ingredients of anabasine, chlorogenic acid, mesaconitine and hypaconitine. The 24h cumulative transdermal …
In-vitro experiment: In the microneedle-roller group and crossbow-medicine liquid application group, the effect of transdermal delivery was …
Rapid determination of five common toxic alkaloids in blood by UPLC-MRM-IDA-EPI: Application to poisoning case.
Zhang S, Chen S, Zhu F, Wang A, Xia B, Wang J, Huang J, Liu Y, Luo P. Zhang S, et al. Leg Med (Tokyo). 2023 Jul;63:102267. doi: 10.1016/j.legalmed.2023.102267. Epub 2023 May 2. Leg Med (Tokyo). 2023. PMID: 37201269
This study developed a method for determining five common toxic alkaloids in blood, including brucine, strychnine, aconitine, mesaconitine, and hypaconitine using ultra-high liquid chromatography-tandem quadrupole/linear ion trap mass spectrometry (QTRAP UPLC-MS/MS). ...
This study developed a method for determining five common toxic alkaloids in blood, including brucine, strychnine, aconitine, mesaconitine, …
The Metabolic Pathways and Products of Ten Aconitum Alkaloids in Sanwujiao Pills from Eight Organs of Mice by UHPLC-Q-TOF-MS/MS.
Pei WH, Huang YF, Xie Y, Qu Y, He F, Zhou H. Pei WH, et al. Curr Drug Metab. 2023;24(4):290-302. doi: 10.2174/1389200224666230505122353. Curr Drug Metab. 2023. PMID: 37151055
METHOD: The biosamples were investigated by a four-step strategy of UPLC-Q-TOF-MS /MS technology. RESULTS: Aconitine (AC), mesaconitine (MA), and hypaconitine (HA) were not detected in any organs. The highest concentrations of the other seven AAs occurred at 0.5 h. ...
METHOD: The biosamples were investigated by a four-step strategy of UPLC-Q-TOF-MS /MS technology. RESULTS: Aconitine (AC), mesaconitine (MA) …
231 results