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Year Number of Results
2019 1
2020 125
2021 250
2022 250
2023 136
2024 32

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711 results

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Efficacy and safety of ivermectin in patients with mild COVID-19 in Japan and Thailand.
Mikamo H, Takahashi S, Yamagishi Y, Hirakawa A, Harada T, Nagashima H, Noguchi C, Masuko K, Maekawa H, Kashii T, Ohbayashi H, Hosokawa S, Maejima K, Yamato M, Manosuthi W, Paiboonpol S, Suganami H, Tanigawa R, Kawamura H; IVERMILCO Study Group. Mikamo H, et al. J Infect Chemother. 2024 Jun;30(6):536-543. doi: 10.1016/j.jiac.2023.12.012. Epub 2023 Dec 27. J Infect Chemother. 2024. PMID: 38154616 Free article. Clinical Trial.
Fundamental research suggests that ivermectin is effective against coronavirus disease 2019 (COVID-19); therefore, we investigated the efficacy and safety of ivermectin as a COVID-19 treatment option. ...CONCLUSIONS: The results sh …
Fundamental research suggests that ivermectin is effective against coronavirus disease 2019 (COVID-19); therefor …
Favorable Antiviral Effect of Metformin on Severe Acute Respiratory Syndrome Coronavirus 2 Viral Load in a Randomized, Placebo-Controlled Clinical Trial of Coronavirus Disease 2019.
Bramante CT, Beckman KB, Mehta T, Karger AB, Odde DJ, Tignanelli CJ, Buse JB, Johnson DM, Watson RHB, Daniel JJ, Liebovitz DM, Nicklas JM, Cohen K, Puskarich MA, Belani HK, Siegel LK, Klatt NR, Anderson B, Hartman KM, Rao V, Hagen AA, Patel B, Fenno SL, Avula N, Reddy NV, Erickson SM, Fricton RD, Lee S, Griffiths G, Pullen MF, Thompson JL, Sherwood NE, Murray TA, Rose MR, Boulware DR, Huling JD; COVID-OUT Study Team. Bramante CT, et al. Clin Infect Dis. 2024 May 1:ciae159. doi: 10.1093/cid/ciae159. Online ahead of print. Clin Infect Dis. 2024. PMID: 38690892
BACKGROUND: Metformin has antiviral activity against RNA viruses including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The mechanism appears to be suppression of protein translation via targeting the …
BACKGROUND: Metformin has antiviral activity against RNA viruses including severe acute respiratory syndrome
A randomized trial to assess the acceleration of viral clearance by the combination Favipiravir/Ivermectin/Niclosamide in mild-to-moderate COVID-19 adult patients (FINCOV).
Siripongboonsitti T, Tawinprai K, Avirutnan P, Jitobaom K, Auewarakul P. Siripongboonsitti T, et al. J Infect Public Health. 2024 May;17(5):897-905. doi: 10.1016/j.jiph.2024.03.030. Epub 2024 Mar 29. J Infect Public Health. 2024. PMID: 38569269 Free article. Clinical Trial.
BACKGROUND: The efficacy of the viral clearance and clinical outcomes of favipiravir (FPV) in outpatients being treated for coronavirus disease 2019 (COVID-19) is unclear. Ivermectin (IVM), niclosamide (NCL), and FPV demonstrated synergistic effects in …
BACKGROUND: The efficacy of the viral clearance and clinical outcomes of favipiravir (FPV) in outpatients being treated for coronavirus
Discovery of common molecular signatures and drug repurposing for COVID-19/Asthma comorbidity: ACE2 and multi-partite networks.
Xu J, Abdulsalam Khaleel R, Zaidan HK, Faisal Mutee A, Fahmi Fawy K, Gehlot A, Abbas AH, Arias Gonzáles JL, Amin AH, Ruiz-Balvin MC, Imannezhad S, Bahrami A, Akhavan-Sigari R. Xu J, et al. Cell Cycle. 2024 Apr 19:1-30. doi: 10.1080/15384101.2024.2340859. Online ahead of print. Cell Cycle. 2024. PMID: 38640424
Angiotensin-converting enzyme 2 (ACE2) is identified as the functional receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the ongoing global coronavirus disease-20 …
Angiotensin-converting enzyme 2 (ACE2) is identified as the functional receptor for severe acute respiratory syndrom
Ivermectin for COVID-19 in adults in the community (PRINCIPLE): An open, randomised, controlled, adaptive platform trial of short- and longer-term outcomes.
Hayward G, Yu LM, Little P, Gbinigie O, Shanyinde M, Harris V, Dorward J, Saville BR, Berry N, Evans PH, Thomas NPB, Patel MG, Richards D, Hecke OV, Detry MA, Saunders C, Fitzgerald M, Robinson J, Latimer-Bell C, Allen J, Ogburn E, Grabey J, de Lusignan S, Hobbs FR, Butler CC; PRINCIPLE Trial Collaborative Group. Hayward G, et al. J Infect. 2024 Apr;88(4):106130. doi: 10.1016/j.jinf.2024.106130. Epub 2024 Feb 29. J Infect. 2024. PMID: 38431155 Free PMC article. Clinical Trial.
BACKGROUND: The evidence for whether ivermectin impacts recovery, hospital admissions, and longer-term outcomes in COVID-19 is contested. ...Further trials of ivermectin for SARS-Cov-2 infection in vaccinated community populations …
BACKGROUND: The evidence for whether ivermectin impacts recovery, hospital admissions, and longer-term outcomes in COVID-19
A remodeled ivermectin polycaprolactone-based nanoparticles for inhalation as a promising treatment of pulmonary inflammatory diseases.
Mohammed SW, El-Megrab NA, Hasan AA, Gomaa E. Mohammed SW, et al. Eur J Pharm Sci. 2024 Apr 1;195:106714. doi: 10.1016/j.ejps.2024.106714. Epub 2024 Jan 30. Eur J Pharm Sci. 2024. PMID: 38301972 Free article.
In recent years, ivermectin (IVM), an antiparasitic drug of low water solubility and poor oral bioavailability, has shown a profound effect on inflammatory mediators involved in diseases, such as acute lung injury, lung fibrosis, and COVID-19. ...
In recent years, ivermectin (IVM), an antiparasitic drug of low water solubility and poor oral bioavailability, has shown a profound …
A guide to COVID-19 antiviral therapeutics: a summary and perspective of the antiviral weapons against SARS-CoV-2 infection.
Brady DK, Gurijala AR, Huang L, Hussain AA, Lingan AL, Pembridge OG, Ratangee BA, Sealy TT, Vallone KT, Clements TP. Brady DK, et al. FEBS J. 2024 Apr;291(8):1632-1662. doi: 10.1111/febs.16662. Epub 2022 Nov 5. FEBS J. 2024. PMID: 36266238 Free PMC article. Review.
Antiviral therapies are integral in the fight against SARS-CoV-2 (i.e. severe acute respiratory syndrome coronavirus 2), the causative agent of COVID-19. ...Learning more about these therapies helps rais …
Antiviral therapies are integral in the fight against SARS-CoV-2 (i.e. severe acute respiratory
Ivermectin for treatment of COVID-19: A systematic review and meta-analysis.
Song Z, Shi S, Zhang Y. Song Z, et al. Heliyon. 2024 Mar 11;10(6):e27647. doi: 10.1016/j.heliyon.2024.e27647. eCollection 2024 Mar 30. Heliyon. 2024. PMID: 38510038 Free PMC article.
The effect of ivermectin (IVM) in treating coronavirus disease 2019 (COVID-19) is still controversial, yet the drug has been widely used in the world. ...There were significant differences in MV requirement (RR 0.67, 95% CI 0.47-0.96) and AEs (RR 0.87, …
The effect of ivermectin (IVM) in treating coronavirus disease 2019 (COVID-19) is still controversial, yet the d …
Scabies in infants and children - a narrative review.
Chiriac A, Diaconeasa A, Miulescu R, Chiriac AE, Wollina U. Chiriac A, et al. Eur J Pediatr. 2024 Mar 27. doi: 10.1007/s00431-024-05535-1. Online ahead of print. Eur J Pediatr. 2024. PMID: 38536458 Review.
Polymerase chain reaction (PCR) is less sensitive and specific than microscopy of skin scrapings. Treatment of choice is topical permethrin 5%. Ivermectin is the only oral drug FDA-approved for scabies. It should be used in cases non-responsive to topical therapy and in ca …
Polymerase chain reaction (PCR) is less sensitive and specific than microscopy of skin scrapings. Treatment of choice is topical permethrin …
Impact of annual community-directed treatment with ivermectin on the incidence of epilepsy in Mvolo, a two-year prospective study.
Amaral LJ, Jada SR, Ndjanfa AK, Carter JY, Abd-Elfarag G, Okaro S, Logora MY, Bol YY, Lakwo T, Fodjo JNS, Colebunders R. Amaral LJ, et al. PLoS Negl Trop Dis. 2024 Mar 21;18(3):e0012059. doi: 10.1371/journal.pntd.0012059. eCollection 2024 Mar. PLoS Negl Trop Dis. 2024. PMID: 38512994 Free PMC article.
The incidence of epilepsy, including pNS, was analysed using 95% confidence intervals (CIs). Data on ivermectin intake and onchocerciasis-associated manifestations (itching and blindness) were collected. ...Coverage of CDTI was suboptimal, reaching only 64.0% of participan …
The incidence of epilepsy, including pNS, was analysed using 95% confidence intervals (CIs). Data on ivermectin intake and onchocerci …
711 results