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Kaempferia parviflora, a plant used in traditional medicine to enhance sexual performance contains large amounts of low affinity PDE5 inhibitors.
Temkitthawon P, Hinds TR, Beavo JA, Viyoch J, Suwanborirux K, Pongamornkul W, Sawasdee P, Ingkaninan K. Temkitthawon P, et al. J Ethnopharmacol. 2011 Oct 11;137(3):1437-41. doi: 10.1016/j.jep.2011.08.025. Epub 2011 Aug 30. J Ethnopharmacol. 2011. PMID: 21884777 Free PMC article.
RESULTS: From forty one plant extracts tested, four showed the PDE5 inhibitory effect. The chemical constituents isolated from rhizomes of Kaempferia parviflora were further investigated on inhibitory activity against PDE5 and PDE6. ...Structure activi …
RESULTS: From forty one plant extracts tested, four showed the PDE5 inhibitory effect. The chemical constituents isolated from rhizom …
Medicinal plants as a potential source of Phosphodiesterase-5 inhibitors: A review.
Anand Ganapathy A, Hari Priya VM, Kumaran A. Anand Ganapathy A, et al. J Ethnopharmacol. 2021 Mar 1;267:113536. doi: 10.1016/j.jep.2020.113536. Epub 2020 Nov 1. J Ethnopharmacol. 2021. PMID: 33137431 Review.
Therefore, the exploration of medicinal plants as PDE5 inhibitors will be worthwhile in tackling the problems as many plant extracts and fractions have been long used as aphrodisiacs and sexual stimulants which may be found to be active against PDE5 enzyme. ...Tradi …
Therefore, the exploration of medicinal plants as PDE5 inhibitors will be worthwhile in tackling the problems as many plant extracts …