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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1968 1
1971 2
1972 8
1973 9
1974 9
1975 20
1976 11
1977 10
1978 13
1979 14
1980 14
1981 13
1982 22
1983 8
1984 24
1985 22
1986 14
1987 22
1988 21
1989 26
1990 31
1991 20
1992 23
1993 14
1994 22
1995 28
1996 20
1997 30
1998 25
1999 22
2000 18
2001 19
2002 22
2003 22
2004 30
2005 25
2006 24
2007 32
2008 38
2009 52
2010 63
2011 74
2012 119
2013 166
2014 204
2015 255
2016 264
2017 303
2018 329
2019 426
2020 554
2021 602
2022 620
2023 692
2024 334

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5,062 results

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Page 1
Ketamine for depression.
Jelen LA, Stone JM. Jelen LA, et al. Int Rev Psychiatry. 2021 May;33(3):207-228. doi: 10.1080/09540261.2020.1854194. Epub 2021 Feb 11. Int Rev Psychiatry. 2021. PMID: 33569971 Review.
Ketamine is a racemic mixture composed of equal amounts of (S)-ketamine and (R)-ketamine. ...A synopsis of some of the putative neurobiological mechanisms underlying ketamine's rapid-acting antidepressant effects is provided before finally outli …
Ketamine is a racemic mixture composed of equal amounts of (S)-ketamine and (R)-ketamine. ...A synopsis of some of the …
Synthesizing the Evidence for Ketamine and Esketamine in Treatment-Resistant Depression: An International Expert Opinion on the Available Evidence and Implementation.
McIntyre RS, Rosenblat JD, Nemeroff CB, Sanacora G, Murrough JW, Berk M, Brietzke E, Dodd S, Gorwood P, Ho R, Iosifescu DV, Lopez Jaramillo C, Kasper S, Kratiuk K, Lee JG, Lee Y, Lui LMW, Mansur RB, Papakostas GI, Subramaniapillai M, Thase M, Vieta E, Young AH, Zarate CA Jr, Stahl S. McIntyre RS, et al. Am J Psychiatry. 2021 May 1;178(5):383-399. doi: 10.1176/appi.ajp.2020.20081251. Epub 2021 Mar 17. Am J Psychiatry. 2021. PMID: 33726522 Free PMC article. Review.
Ketamine and esketamine represent pharmacologically novel treatment avenues for adults with treatment-resistant depression. In addition to providing hope to affected persons, these agents represent the first non-monoaminergic agents with proven rapid-onset ef …
Ketamine and esketamine represent pharmacologically novel treatment avenues for adults with treatment-resistant depression …
Comparative efficacy of racemic ketamine and esketamine for depression: A systematic review and meta-analysis.
Bahji A, Vazquez GH, Zarate CA Jr. Bahji A, et al. J Affect Disord. 2021 Jan 1;278:542-555. doi: 10.1016/j.jad.2020.09.071. Epub 2020 Sep 23. J Affect Disord. 2021. PMID: 33022440 Free PMC article. Review.
BACKGROUND: Ketamine appears to have a therapeutic role in certain mental disorders, most notably depression. ...RR = 1.47), as well as lower dropouts (RR = 0.76 vs. RR = 1.37). CONCLUSIONS: Intravenous ketamine appears to be more efficacious than intranasal …
BACKGROUND: Ketamine appears to have a therapeutic role in certain mental disorders, most notably depression. ...RR = 1.47), a …
Maintenance ketamine treatment for depression: a systematic review of efficacy, safety, and tolerability.
Smith-Apeldoorn SY, Veraart JK, Spijker J, Kamphuis J, Schoevers RA. Smith-Apeldoorn SY, et al. Lancet Psychiatry. 2022 Nov;9(11):907-921. doi: 10.1016/S2215-0366(22)00317-0. Lancet Psychiatry. 2022. PMID: 36244360 Review.
Ketamine has rapid yet often transient antidepressant effects in patients with treatment-resistant depression. Different strategies have been proposed to prolong these effects. Maintenance ketamine treatment appears promising, but little is known about its ef …
Ketamine has rapid yet often transient antidepressant effects in patients with treatment-resistant depression. Different strat …
Oral ketamine for depression: An updated systematic review.
Meshkat S, Haikazian S, Di Vincenzo JD, Fancy F, Johnson D, Chen-Li D, McIntyre RS, Mansur R, Rosenblat JD. Meshkat S, et al. World J Biol Psychiatry. 2023 Sep-Oct;24(7):545-557. doi: 10.1080/15622975.2023.2169349. Epub 2023 Jan 31. World J Biol Psychiatry. 2023. PMID: 36651238 Review.
Objectives: Ketamine is a glutamate N-methyl-D-aspartate receptor antagonist that can be used to treat major depressive disorder by single or repeated infusions. However, the accessibility and scalability of oral ketamine make it preferred over intrave …
Objectives: Ketamine is a glutamate N-methyl-D-aspartate receptor antagonist that can be used to treat major depressive dis …
Use of ketamine and esketamine for depression: an overview of systematic reviews with meta-analyses.
Lima TM, Visacri MB, Aguiar PM. Lima TM, et al. Eur J Clin Pharmacol. 2022 Mar;78(3):311-338. doi: 10.1007/s00228-021-03216-8. Epub 2021 Oct 27. Eur J Clin Pharmacol. 2022. PMID: 34705064 Review.
PURPOSE: To summarize the evidence of efficacy and safety of the use of ketamine and esketamine for depression. METHODS: A literature search was performed in Medline, the Cochrane Library, LILACS, and CRD until November 2020. ...Ketamine and esketam …
PURPOSE: To summarize the evidence of efficacy and safety of the use of ketamine and esketamine for depression. METHODS …
Ketamine for Depression in Older Adults.
Subramanian S, Lenze EJ. Subramanian S, et al. Am J Geriatr Psychiatry. 2021 Sep;29(9):914-916. doi: 10.1016/j.jagp.2021.01.005. Epub 2021 Jan 19. Am J Geriatr Psychiatry. 2021. PMID: 33509675 No abstract available.
Ketamine as a therapeutic agent for depression and pain: mechanisms and evidence.
Subramanian S, Haroutounian S, Palanca BJA, Lenze EJ. Subramanian S, et al. J Neurol Sci. 2022 Mar 15;434:120152. doi: 10.1016/j.jns.2022.120152. Epub 2022 Jan 14. J Neurol Sci. 2022. PMID: 35092901
Ketamine is an anesthetic drug which is now used to treat chronic pain conditions and psychiatric disorders, especially depression. ...Many clinical trials have utilized intravenous or intranasal ketamine for treating depression and pain. Intravenous …
Ketamine is an anesthetic drug which is now used to treat chronic pain conditions and psychiatric disorders, especially depression …
Ketamine for resistant depression: a scoping review.
Eduardo TQ, Angela A, Mateo L, Melanie LZ, Valentina PF, David C, Estefania C, Natalia RS, Andrés VC, Angel RO, Juan G, Juan P. Eduardo TQ, et al. Actas Esp Psiquiatr. 2022 May;50(3):144-159. Epub 2022 May 1. Actas Esp Psiquiatr. 2022. PMID: 35643973 Free PMC article. Review.
Ketamine is a fast-acting anesthetic with hypnotic properties. Moreover, could potentially improve affective symptoms in patients with refractory depressive disorder. Objective. explore the scientific literature available until December 10, 2021, about the ef …
Ketamine is a fast-acting anesthetic with hypnotic properties. Moreover, could potentially improve affective symptoms in patients wit …
Ketamine and other glutamate receptor modulators for depression in adults with unipolar major depressive disorder.
Dean RL, Hurducas C, Hawton K, Spyridi S, Cowen PJ, Hollingsworth S, Marquardt T, Barnes A, Smith R, McShane R, Turner EH, Cipriani A. Dean RL, et al. Cochrane Database Syst Rev. 2021 Sep 12;9(9):CD011612. doi: 10.1002/14651858.CD011612.pub3. Cochrane Database Syst Rev. 2021. PMID: 34510411 Free PMC article. Review.
This is an update of a review first published in 2015 focusing on the use of glutamate receptor modulators in unipolar depression. OBJECTIVES: To assess the effects - and review the acceptability and tolerability - of ketamine and other glutamate receptor modulators …
This is an update of a review first published in 2015 focusing on the use of glutamate receptor modulators in unipolar depression. OB …
5,062 results