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Showing results for l asparaginase
Search for l-asparaginaze instead (2 results)
A Comprehensive Review on L-Asparaginase and Its Applications.
Batool T, Makky EA, Jalal M, Yusoff MM. Batool T, et al. Appl Biochem Biotechnol. 2016 Mar;178(5):900-23. doi: 10.1007/s12010-015-1917-3. Epub 2015 Nov 7. Appl Biochem Biotechnol. 2016. PMID: 26547852 Review.
L-asparaginase (LA) catalyzes the degradation of asparagine, an essential amino acid for leukemic cells, into ammonia and aspartate. ...Pieces of information about the three-dimensional structure of L-asparaginase from Escherichia coli and Erwinia sp. …
L-asparaginase (LA) catalyzes the degradation of asparagine, an essential amino acid for leukemic cells, into ammonia and aspa …
L-asparaginase-mediated Therapy in L-asparagine Auxotrophic Cancers: A Review.
Sindhu R, Manonmani HK. Sindhu R, et al. Anticancer Agents Med Chem. 2022;22(13):2393-2410. doi: 10.2174/1871520622666220106103336. Anticancer Agents Med Chem. 2022. PMID: 34994334 Review.
Microbial L-asparaginase is the most effective first-line therapy used in the treatment protocols of paediatric and adult leukemia. Leukemic cells' auxotrophy for L-asparagine is exploited as a therapeutic strategy to mediate cell death through metabolic blockade of …
Microbial L-asparaginase is the most effective first-line therapy used in the treatment protocols of paediatric and adult leuk …
L-Asparaginase delivery systems targeted to minimize its side-effects.
Talluri VP, Mutaliyeva B, Sharipova A, Ulaganathan V, Lanka SS, Aidarova S, Suigenbayeva A, Tleuova A. Talluri VP, et al. Adv Colloid Interface Sci. 2023 Jun;316:102915. doi: 10.1016/j.cis.2023.102915. Epub 2023 May 3. Adv Colloid Interface Sci. 2023. PMID: 37159987 Review.
L-asparaginase (L-ASP) is one of the key enzymes used in therapeutic applications, particularly to treat Acute Lymphocytic Leukemia (ALL). ...
L-asparaginase (L-ASP) is one of the key enzymes used in therapeutic applications, particularly to treat Acute Lymphocytic Leu …
L-Asparaginase as the gold standard in the treatment of acute lymphoblastic leukemia: a comprehensive review.
Tosta Pérez M, Herrera Belén L, Letelier P, Calle Y, Pessoa A, Farías JG. Tosta Pérez M, et al. Med Oncol. 2023 Apr 15;40(5):150. doi: 10.1007/s12032-023-02014-9. Med Oncol. 2023. PMID: 37060469 Review.
L-Asparaginase is an antileukemic drug long approved for clinical use to treat childhood acute lymphoblastic leukemia, the most common cancer in this population worldwide. ...For this reason, the search for new, less immunogenic variants has long been the subject of …
L-Asparaginase is an antileukemic drug long approved for clinical use to treat childhood acute lymphoblastic leukemia, the mos …
Circumventing the side effects of L-asparaginase.
Fonseca MHG, Fiúza TDS, Morais SB, Souza TACB, Trevizani R. Fonseca MHG, et al. Biomed Pharmacother. 2021 Jul;139:111616. doi: 10.1016/j.biopha.2021.111616. Epub 2021 Apr 28. Biomed Pharmacother. 2021. PMID: 33932739 Free article. Review.
L-asparaginase is an enzyme that catalyzes the degradation of asparagine and successfully used in the treatment of acute lymphoblastic leukemia. ...PEGylated versions have been incorporated into the treatment protocols to reduce immunogenicity and an alternative …
L-asparaginase is an enzyme that catalyzes the degradation of asparagine and successfully used in the treatment of acute lymph …
Structural and biochemical properties of L-asparaginase.
Lubkowski J, Wlodawer A. Lubkowski J, et al. FEBS J. 2021 Jul;288(14):4183-4209. doi: 10.1111/febs.16042. Epub 2021 Jun 19. FEBS J. 2021. PMID: 34060231 Free article. Review.
l-Asparaginase (a hydrolase converting l-asparagine to l-aspartic acid) was the first enzyme to be used in clinical practice as an anticancer agent after its approval in 1978 as a component of a treatment protocol for childhood acute lymphoblastic leukemia. ...
l-Asparaginase (a hydrolase converting l-asparagine to l-aspartic acid) was the first enzyme to be used in clinical practice a …
Therapeutic l-asparaginase: upstream, downstream and beyond.
Lopes AM, Oliveira-Nascimento L, Ribeiro A, Tairum CA Jr, Breyer CA, Oliveira MA, Monteiro G, Souza-Motta CM, Magalhães PO, Avendaño JG, Cavaco-Paulo AM, Mazzola PG, Rangel-Yagui CO, Sette LD, Converti A, Pessoa A. Lopes AM, et al. Crit Rev Biotechnol. 2017 Feb;37(1):82-99. doi: 10.3109/07388551.2015.1120705. Epub 2015 Dec 23. Crit Rev Biotechnol. 2017. PMID: 26694875 Review.
l-asparaginase (l-asparagine amino hydrolase, E.C.3.5.1.1) is an enzyme clinically accepted as an antitumor agent to treat acute lymphoblastic leukemia and lymphosarcoma. It catalyzes l-asparagine (Asn) hydrolysis to l-aspartate and ammonia, and Asn effective deplet …
l-asparaginase (l-asparagine amino hydrolase, E.C.3.5.1.1) is an enzyme clinically accepted as an antitumor agent to treat acu …
Microbial L-asparaginase: purification, characterization and applications.
Muneer F, Siddique MH, Azeem F, Rasul I, Muzammil S, Zubair M, Afzal M, Nadeem H. Muneer F, et al. Arch Microbiol. 2020 Jul;202(5):967-981. doi: 10.1007/s00203-020-01814-1. Epub 2020 Feb 12. Arch Microbiol. 2020. PMID: 32052094 Review.
L-asparaginase (E.C.3.5.1.1) is an important enzyme that has been purified and characterized for over decades to study and evaluate its anti-carcinogenic activity against different lymphoproliferative disorders such as acute lymphoblastic leukemia (ALL) and Hodgkin' …
L-asparaginase (E.C.3.5.1.1) is an important enzyme that has been purified and characterized for over decades to study and eva …
L-asparaginase--antileukemia agent.
Bukhari SZ, Yaqub M. Bukhari SZ, et al. J Pak Med Assoc. 1977 Jan;27(1):262-4. J Pak Med Assoc. 1977. PMID: 19639 Review.
This paper describes the most recent development in the field of biosynthesis of L-Asparaginase by means of various culture, purification by Column Chromatography, informations of the Catabolite repression of L-Asparaginase and its metabolism in mycoba …
This paper describes the most recent development in the field of biosynthesis of L-Asparaginase by means of various culture, p …
L-asparaginase.
Whitecar JP Jr, Bodey GP, Harris JE, Freireich EJ. Whitecar JP Jr, et al. N Engl J Med. 1970 Mar 26;282(13):732-4. doi: 10.1056/NEJM197003262821307. N Engl J Med. 1970. PMID: 4906449 Review. No abstract available.
6,806 results