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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1916 1
1919 1
1924 1
1925 1
1926 1
1928 1
1929 2
1931 2
1932 7
1933 2
1936 1
1942 4
1943 2
1944 3
1945 3
1946 7
1947 18
1948 13
1949 15
1950 16
1951 19
1952 39
1953 36
1954 41
1955 27
1956 60
1957 64
1958 71
1959 110
1960 137
1961 158
1962 185
1963 304
1964 556
1965 686
1966 1084
1967 1335
1968 1518
1969 1746
1970 1714
1971 1942
1972 2046
1973 2065
1974 2060
1975 2125
1976 1881
1977 1823
1978 1712
1979 1679
1980 1638
1981 1582
1982 1633
1983 1777
1984 1924
1985 1915
1986 2058
1987 1920
1988 1977
1989 2188
1990 2219
1991 2348
1992 2344
1993 2380
1994 2481
1995 2363
1996 2409
1997 2346
1998 2280
1999 2423
2000 2612
2001 2575
2002 2649
2003 2790
2004 2830
2005 3142
2006 3444
2007 3612
2008 3663
2009 3870
2010 4213
2011 4593
2012 4937
2013 5128
2014 5389
2015 5581
2016 5573
2017 5450
2018 5752
2019 5799
2020 6094
2021 5720
2022 4814
2023 4479
2024 2543
2025 1

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162,862 results

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Page 1
Lactate: the ugly duckling of energy metabolism.
Rabinowitz JD, Enerbäck S. Rabinowitz JD, et al. Nat Metab. 2020 Jul;2(7):566-571. doi: 10.1038/s42255-020-0243-4. Epub 2020 Jul 20. Nat Metab. 2020. PMID: 32694798 Free PMC article. Review.
Lactate, perhaps the best-known metabolic waste product, was first isolated from sour milk, in which it is produced by lactobacilli. ...The build-up of lactate in stressed muscle and ischaemic tissues has established lactate's reputation as a de …
Lactate, perhaps the best-known metabolic waste product, was first isolated from sour milk, in which it is produced by lactoba …
Lactate as a fulcrum of metabolism.
Brooks GA. Brooks GA. Redox Biol. 2020 Aug;35:101454. doi: 10.1016/j.redox.2020.101454. Epub 2020 Feb 9. Redox Biol. 2020. PMID: 32113910 Free PMC article. Review.
By inhibiting lipolysis in adipose via HCAR-1, and muscle mitochondrial fatty acid uptake via malonyl-CoA and CPT1, lactate controls energy substrate partitioning. ...Lactate is the fulcrum of metabolic regulation in vivo....
By inhibiting lipolysis in adipose via HCAR-1, and muscle mitochondrial fatty acid uptake via malonyl-CoA and CPT1, lactate co …
The Science and Translation of Lactate Shuttle Theory.
Brooks GA. Brooks GA. Cell Metab. 2018 Apr 3;27(4):757-785. doi: 10.1016/j.cmet.2018.03.008. Cell Metab. 2018. PMID: 29617642 Free article. Review.
Once thought to be a waste product of anaerobic metabolism, lactate is now known to form continuously under aerobic conditions. ...The above, as well as historic and recent studies of lactate metabolism and shuttling, are discussed in the following rev …
Once thought to be a waste product of anaerobic metabolism, lactate is now known to form continuously under aerobic conditions …
Lactate Metabolism, Signaling, and Function in Brain Development, Synaptic Plasticity, Angiogenesis, and Neurodegenerative Diseases.
Wu A, Lee D, Xiong WC. Wu A, et al. Int J Mol Sci. 2023 Aug 29;24(17):13398. doi: 10.3390/ijms241713398. Int J Mol Sci. 2023. PMID: 37686202 Free PMC article. Review.
The astrocyte-neuron lactate-shuttle hypothesis states that lactate, once released into the extracellular space by astrocytes, can be up-taken and metabolized by neurons. This review focuses on this hypothesis, highlighting lactate's emerging ro …
The astrocyte-neuron lactate-shuttle hypothesis states that lactate, once released into the extracellular space by astrocytes, …
Lactate: Friend or Foe.
Hall MM, Rajasekaran S, Thomsen TW, Peterson AR. Hall MM, et al. PM R. 2016 Mar;8(3 Suppl):S8-S15. doi: 10.1016/j.pmrj.2015.10.018. PM R. 2016. PMID: 26972271 Review.
Lactic acid has played an important role in the traditional theory of muscle fatigue and limitation of endurance exercise performance. ...This review will provide the sports medicine clinician with an understanding of contemporary lactate theories, including …
Lactic acid has played an important role in the traditional theory of muscle fatigue and limitation of endurance exercise perf …
Brain lactate metabolism: the discoveries and the controversies.
Dienel GA. Dienel GA. J Cereb Blood Flow Metab. 2012 Jul;32(7):1107-38. doi: 10.1038/jcbfm.2011.175. Epub 2011 Dec 21. J Cereb Blood Flow Metab. 2012. PMID: 22186669 Free PMC article. Review.
Brain activation in subjects with low plasma lactate causes outward, brain-to-blood lactate gradients, and lactate is quickly released in substantial amounts. Lactate utilization by the adult brain increases during lactate infusions and strenuou …
Brain activation in subjects with low plasma lactate causes outward, brain-to-blood lactate gradients, and lactate is q …
Effect of water-based recovery on blood lactate removal after high-intensity exercise.
Lucertini F, Gervasi M, D'Amen G, Sisti D, Rocchi MBL, Stocchi V, Benelli P. Lucertini F, et al. PLoS One. 2017 Sep 6;12(9):e0184240. doi: 10.1371/journal.pone.0184240. eCollection 2017. PLoS One. 2017. PMID: 28877225 Free PMC article. Clinical Trial.
Blood lactate concentration was measured 8 times during each recovery condition and lactate clearance was modeled over a negative exponential function using non-linear regression. ...Non-linear regression parameters (coefficients of the exponential decay of lacta …
Blood lactate concentration was measured 8 times during each recovery condition and lactate clearance was modeled over a negat …
The emerging era of lactate: A rising star in cellular signaling and its regulatory mechanisms.
Wu D, Zhang K, Khan FA, Wu Q, Pandupuspitasari NS, Tang Y, Guan K, Sun F, Huang C. Wu D, et al. J Cell Biochem. 2023 Aug;124(8):1067-1081. doi: 10.1002/jcb.30458. Epub 2023 Aug 11. J Cell Biochem. 2023. PMID: 37566665 Review.
Beyond their cognate roles, they have signaling functions as the ligands for specific receptors and the precursors for epigenetic or posttranslational modifications. Lactate has long been recognized as a metabolic waste and fatigue product mainly produced from glyco …
Beyond their cognate roles, they have signaling functions as the ligands for specific receptors and the precursors for epigenetic or posttra …
Lactate metabolism in acute uremia.
Leverve X, Mustafa I, Novak I, Krouzecky A, Rokyta R, Matejovic M, Ichai C. Leverve X, et al. J Ren Nutr. 2005 Jan;15(1):58-62. doi: 10.1053/j.jrn.2004.09.023. J Ren Nutr. 2005. PMID: 15648009
The metabolic disorders related to acute renal failure or associated with it, such as liver failure, may affect lactate metabolism, and therefore they are often regarded as limiting factors for the use of lactate-containing fluids in such patients. By …
The metabolic disorders related to acute renal failure or associated with it, such as liver failure, may affect lactate met …
162,862 results
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Searches related to "lactate metabolism"