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Chromatin compartmentalization regulates the response to DNA damage.
Arnould C, Rocher V, Saur F, Bader AS, Muzzopappa F, Collins S, Lesage E, Le Bozec B, Puget N, Clouaire T, Mangeat T, Mourad R, Ahituv N, Noordermeer D, Erdel F, Bushell M, Marnef A, Legube G. Arnould C, et al. Among authors: legube g. Nature. 2023 Nov;623(7985):183-192. doi: 10.1038/s41586-023-06635-y. Epub 2023 Oct 18. Nature. 2023. PMID: 37853125 Free PMC article.
Loop extrusion as a mechanism for formation of DNA damage repair foci.
Arnould C, Rocher V, Finoux AL, Clouaire T, Li K, Zhou F, Caron P, Mangeot PE, Ricci EP, Mourad R, Haber JE, Noordermeer D, Legube G. Arnould C, et al. Among authors: legube g. Nature. 2021 Feb;590(7847):660-665. doi: 10.1038/s41586-021-03193-z. Epub 2021 Feb 17. Nature. 2021. PMID: 33597753 Free PMC article.
Comprehensive Mapping of Histone Modifications at DNA Double-Strand Breaks Deciphers Repair Pathway Chromatin Signatures.
Clouaire T, Rocher V, Lashgari A, Arnould C, Aguirrebengoa M, Biernacka A, Skrzypczak M, Aymard F, Fongang B, Dojer N, Iacovoni JS, Rowicka M, Ginalski K, Côté J, Legube G. Clouaire T, et al. Among authors: legube g. Mol Cell. 2018 Oct 18;72(2):250-262.e6. doi: 10.1016/j.molcel.2018.08.020. Epub 2018 Sep 27. Mol Cell. 2018. PMID: 30270107 Free PMC article.
Genome editing in primary cells and in vivo using viral-derived Nanoblades loaded with Cas9-sgRNA ribonucleoproteins.
Mangeot PE, Risson V, Fusil F, Marnef A, Laurent E, Blin J, Mournetas V, Massouridès E, Sohier TJM, Corbin A, Aubé F, Teixeira M, Pinset C, Schaeffer L, Legube G, Cosset FL, Verhoeyen E, Ohlmann T, Ricci EP. Mangeot PE, et al. Among authors: legube g. Nat Commun. 2019 Jan 3;10(1):45. doi: 10.1038/s41467-018-07845-z. Nat Commun. 2019. PMID: 30604748 Free PMC article.
Chromatin organization drives the search mechanism of nuclear factors.
Mazzocca M, Loffreda A, Colombo E, Fillot T, Gnani D, Falletta P, Monteleone E, Capozi S, Bertrand E, Legube G, Lavagnino Z, Tacchetti C, Mazza D. Mazzocca M, et al. Among authors: legube g. Nat Commun. 2023 Oct 13;14(1):6433. doi: 10.1038/s41467-023-42133-5. Nat Commun. 2023. PMID: 37833263 Free PMC article.
Taming Tricky DSBs: ATM on duty.
Clouaire T, Marnef A, Legube G. Clouaire T, et al. Among authors: legube g. DNA Repair (Amst). 2017 Aug;56:84-91. doi: 10.1016/j.dnarep.2017.06.010. Epub 2017 Jun 9. DNA Repair (Amst). 2017. PMID: 28624372 Free article. Review.
Mitotic DNA synthesis is caused by transcription-replication conflicts in BRCA2-deficient cells.
Groelly FJ, Dagg RA, Petropoulos M, Rossetti GG, Prasad B, Panagopoulos A, Paulsen T, Karamichali A, Jones SE, Ochs F, Dionellis VS, Puig Lombardi E, Miossec MJ, Lockstone H, Legube G, Blackford AN, Altmeyer M, Halazonetis TD, Tarsounas M. Groelly FJ, et al. Among authors: legube g. Mol Cell. 2022 Sep 15;82(18):3382-3397.e7. doi: 10.1016/j.molcel.2022.07.011. Epub 2022 Aug 23. Mol Cell. 2022. PMID: 36002001 Free PMC article.
DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells.
He YJ, Meghani K, Caron MC, Yang C, Ronato DA, Bian J, Sharma A, Moore J, Niraj J, Detappe A, Doench JG, Legube G, Root DE, D'Andrea AD, Drané P, De S, Konstantinopoulos PA, Masson JY, Chowdhury D. He YJ, et al. Among authors: legube g. Nature. 2018 Nov;563(7732):522-526. doi: 10.1038/s41586-018-0670-5. Epub 2018 Oct 31. Nature. 2018. PMID: 30464262 Free PMC article.
Author Correction: Chromatin compartmentalization regulates the response to DNA damage.
Arnould C, Rocher V, Saur F, Bader AS, Muzzopappa F, Collins S, Lesage E, Le Bozec B, Puget N, Clouaire T, Mangeat T, Mourad R, Ahituv N, Noordermeer D, Erdel F, Bushell M, Marnef A, Legube G. Arnould C, et al. Among authors: legube g. Nature. 2023 Dec;624(7990):E1. doi: 10.1038/s41586-023-06841-8. Nature. 2023. PMID: 37974007 Free PMC article. No abstract available.
59 results