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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1926 1
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1965 1
1967 1
1968 1
1969 4
1970 3
1973 1
1974 3
1975 4
1976 3
1977 5
1978 2
1979 4
1980 1
1981 3
1982 4
1983 5
1984 2
1985 1
1986 4
1987 5
1989 11
1990 4
1991 8
1992 2
1993 3
1994 4
1995 10
1996 5
1997 6
1998 9
1999 5
2000 7
2001 4
2002 7
2003 5
2004 12
2005 15
2006 8
2007 12
2008 17
2009 8
2010 18
2011 12
2012 13
2013 12
2014 7
2015 16
2016 9
2017 12
2018 18
2019 21
2020 20
2021 20
2022 13
2023 10
2024 6

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394 results

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Page 1
New Vistas in the Biology of the Flagellum-Leishmania Parasites.
Landfear SM. Landfear SM. Pathogens. 2022 Apr 7;11(4):447. doi: 10.3390/pathogens11040447. Pathogens. 2022. PMID: 35456123 Free PMC article. Review.
Like other kinetoplastid protozoa, the flagellum in Leishmania parasites plays central roles throughout the life cycle. ...This focused review will highlight recent advances that contribute to understanding flagellar function in the various biological contexts encou …
Like other kinetoplastid protozoa, the flagellum in Leishmania parasites plays central roles throughout the life cycle. ...Thi …
Nutrient sensing in Leishmania: Flagellum and cytosol.
Kelly FD, Yates PA, Landfear SM. Kelly FD, et al. Mol Microbiol. 2021 May;115(5):849-859. doi: 10.1111/mmi.14635. Epub 2020 Nov 21. Mol Microbiol. 2021. PMID: 33112443 Free PMC article. Review.
Hence, sensing and acquiring nutrients for which the parasite and host compete is central to the parasitic mode of existence. Leishmania are flagellated kinetoplastid parasites that parasitize phagocytic cells, principally macrophages, of vertebrate hosts and the alimentar …
Hence, sensing and acquiring nutrients for which the parasite and host compete is central to the parasitic mode of existence. Leishmania …
Flagellum assembly and function during the Leishmania life cycle.
Gluenz E, Ginger ML, McKean PG. Gluenz E, et al. Curr Opin Microbiol. 2010 Aug;13(4):473-9. doi: 10.1016/j.mib.2010.05.008. Epub 2010 Jun 11. Curr Opin Microbiol. 2010. PMID: 20541962 Review.
During a complex digenetic life cycle flagellated Leishmania parasites alternate between promastigote and amastigote forms which differ significantly in cellular morphology and flagellum length. Recent studies have provided important new insights into mechanisms by …
During a complex digenetic life cycle flagellated Leishmania parasites alternate between promastigote and amastigote forms which diff …
The single flagellum of Leishmania has a fixed polarisation of its asymmetric beat.
Wang Z, Beneke T, Gluenz E, Wheeler RJ. Wang Z, et al. J Cell Sci. 2020 Oct 22;133(20):jcs246637. doi: 10.1242/jcs.246637. J Cell Sci. 2020. PMID: 33093230 Free PMC article.
Eukaryotic flagella undertake different beat types as necessary for different functions; for example, the Leishmania parasite flagellum undergoes a symmetric tip-to-base beat for forward swimming and an asymmetric base-to-tip beat to rotate the cell. ...Polar …
Eukaryotic flagella undertake different beat types as necessary for different functions; for example, the Leishmania parasite …
Disruption of Leishmania flagellum attachment zone architecture causes flagellum loss.
Halliday C, de Liz LV, Vaughan S, Sunter JD. Halliday C, et al. Mol Microbiol. 2024 Jan;121(1):53-68. doi: 10.1111/mmi.15199. Epub 2023 Nov 27. Mol Microbiol. 2024. PMID: 38010644 Free PMC article.
We identified 27 FAZ proteins and our deletion analysis showed that deletion of two FAZ proteins in the flagellum, FAZ27 and FAZ34 resulted in a reduction in cell body size, and flagellum loss in some cells. ...This process of adaptation has important implications f …
We identified 27 FAZ proteins and our deletion analysis showed that deletion of two FAZ proteins in the flagellum, FAZ27 and FAZ34 re …
Leishmania flagellum attachment zone is critical for flagellar pocket shape, development in the sand fly, and pathogenicity in the host.
Sunter JD, Yanase R, Wang Z, Catta-Preta CMC, Moreira-Leite F, Myskova J, Pruzinova K, Volf P, Mottram JC, Gull K. Sunter JD, et al. Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6351-6360. doi: 10.1073/pnas.1812462116. Epub 2019 Mar 8. Proc Natl Acad Sci U S A. 2019. PMID: 30850532 Free PMC article.
The Leishmania FP has a bulbous region posterior to the FP collar and a distal neck region where the FP membrane surrounds the flagellum more closely. The flagellum is attached to one side of the FP neck by the short flagellum attachment zone (FAZ). .. …
The Leishmania FP has a bulbous region posterior to the FP collar and a distal neck region where the FP membrane surrounds the fla …
Role for the flagellum attachment zone in Leishmania anterior cell tip morphogenesis.
Halliday C, Yanase R, Catta-Preta CMC, Moreira-Leite F, Myskova J, Pruzinova K, Volf P, Mottram JC, Sunter JD. Halliday C, et al. PLoS Pathog. 2020 Oct 22;16(10):e1008494. doi: 10.1371/journal.ppat.1008494. eCollection 2020 Oct. PLoS Pathog. 2020. PMID: 33091070 Free PMC article.
The shape of the Leishmania cell is defined by the sub-pellicular microtubule array and the positioning of the nucleus, kinetoplast and the flagellum within this array. ...Within the flagellar pocket the flagellum is laterally attached to the side of the flag …
The shape of the Leishmania cell is defined by the sub-pellicular microtubule array and the positioning of the nucleus, kinetoplast a …
Isolation of Leishmania Promastigote Flagella.
Beneke T, Demay F, Wheeler RJ, Gluenz E. Beneke T, et al. Methods Mol Biol. 2020;2116:485-495. doi: 10.1007/978-1-0716-0294-2_29. Methods Mol Biol. 2020. PMID: 32221938
Leishmania possess a single flagellum at all stages of their life cycle. ...This protocol describes a simple method for the isolation of Leishmania mexicana promastigote flagella, optimized to yield intact flagella that retain both the cytoskele …
Leishmania possess a single flagellum at all stages of their life cycle. ...This protocol describes a simple method for the is …
Assembly of the Leishmania amazonensis flagellum during cell differentiation.
Gadelha AP, Cunha-e-Silva NL, de Souza W. Gadelha AP, et al. J Struct Biol. 2013 Nov;184(2):280-92. doi: 10.1016/j.jsb.2013.09.006. Epub 2013 Sep 14. J Struct Biol. 2013. PMID: 24041804 Free article.
In contrast to promastigotes, which contain a long and motile flagellum, the amastigote form of Leishmania displays a short flagellum without a PFR that is limited to the flagellar pocket domain. Here, we investigated the biogenesis of the Leishmania …
In contrast to promastigotes, which contain a long and motile flagellum, the amastigote form of Leishmania displays a short …
The kinesin of the flagellum attachment zone in Leishmania is required for cell morphogenesis, cell division and virulence in the mammalian host.
Corrales RM, Vaselek S, Neish R, Berry L, Brunet CD, Crobu L, Kuk N, Mateos-Langerak J, Robinson DR, Volf P, Mottram JC, Sterkers Y, Bastien P. Corrales RM, et al. PLoS Pathog. 2021 Jun 18;17(6):e1009666. doi: 10.1371/journal.ppat.1009666. eCollection 2021 Jun. PLoS Pathog. 2021. PMID: 34143858 Free PMC article.
Leishmania parasites possess a unique and complex cytoskeletal structure termed flagellum attachment zone (FAZ) connecting the base of the flagellum to one side of the flagellar pocket (FP), an invagination of the cell body membrane and the sole site for endo …
Leishmania parasites possess a unique and complex cytoskeletal structure termed flagellum attachment zone (FAZ) connecting the …
394 results