Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1986 1
1987 1
1988 1
1992 3
1994 2
1999 1
2000 2
2001 3
2003 2
2004 1
2006 4
2007 5
2008 7
2009 6
2010 3
2011 4
2012 7
2013 4
2014 8
2015 6
2016 12
2017 14
2018 13
2019 10
2020 30
2021 60
2022 59
2023 61
2024 22

Text availability

Article attribute

Article type

Publication date

Search Results

309 results

Results by year

Filters applied: . Clear all
Page 1
The impact of loneliness and social isolation on the development of cognitive decline and Alzheimer's Disease.
Ren Y, Savadlou A, Park S, Siska P, Epp JR, Sargin D. Ren Y, et al. Front Neuroendocrinol. 2023 Apr;69:101061. doi: 10.1016/j.yfrne.2023.101061. Epub 2023 Feb 8. Front Neuroendocrinol. 2023. PMID: 36758770 Free article. Review.
Alzheimer's Disease (AD) is the leading cause of dementia, observed at a higher incidence in women compared with men. ...Isolation and loneliness have been identified among the major risk factors for AD. ...
Alzheimer's Disease (AD) is the leading cause of dementia, observed at a higher incidence in women compared with men. . …
Associations of loneliness with risk of Alzheimer's disease dementia in the Framingham Heart Study.
Akhter-Khan SC, Tao Q, Ang TFA, Itchapurapu IS, Alosco ML, Mez J, Piers RJ, Steffens DC, Au R, Qiu WQ. Akhter-Khan SC, et al. Alzheimers Dement. 2021 Oct;17(10):1619-1627. doi: 10.1002/alz.12327. Epub 2021 Mar 24. Alzheimers Dement. 2021. PMID: 33760348 Free PMC article.
INTRODUCTION: The relationship between persistent loneliness and Alzheimer's disease (AD) is unclear. We examined the relationship between different types of mid-life loneliness and the development of dementia and AD. ...We defined loneliness …
INTRODUCTION: The relationship between persistent loneliness and Alzheimer's disease (AD) is unclear. We examine …
Social networks and loneliness in people with Alzheimer's dementia.
Balouch S, Rifaat E, Chen HL, Tabet N. Balouch S, et al. Int J Geriatr Psychiatry. 2019 May;34(5):666-673. doi: 10.1002/gps.5065. Epub 2019 Feb 28. Int J Geriatr Psychiatry. 2019. PMID: 30706526
OBJECTIVES: Modifiable lifestyle risk factors are of great interest in the prevention and management of Alzheimer's disease (AD). Loneliness and social networks may influence onset of AD, but little is known about this relationship in people with AD. . …
OBJECTIVES: Modifiable lifestyle risk factors are of great interest in the prevention and management of Alzheimer's disease …
Association between hearing aid use and all-cause and cause-specific dementia: an analysis of the UK Biobank cohort.
Jiang F, Mishra SR, Shrestha N, Ozaki A, Virani SS, Bright T, Kuper H, Zhou C, Zhu D. Jiang F, et al. Lancet Public Health. 2023 May;8(5):e329-e338. doi: 10.1016/S2468-2667(23)00048-8. Epub 2023 Apr 14. Lancet Public Health. 2023. PMID: 37062296 Free article. Retracted.
We used Cox proportional hazards models to estimate hazard ratios (HRs) and 95% CIs between self-reported hearing aid use status (hearing loss with or without hearing aids) at baseline and risk of dementia (all-cause dementia, Alzheimer's disease, vascular de …
We used Cox proportional hazards models to estimate hazard ratios (HRs) and 95% CIs between self-reported hearing aid use status (hearing lo …
Hallucinations, loneliness, and social isolation in Alzheimer's disease.
El Haj M, Jardri R, Larøi F, Antoine P. El Haj M, et al. Cogn Neuropsychiatry. 2016;21(1):1-13. doi: 10.1080/13546805.2015.1121139. Epub 2016 Jan 6. Cogn Neuropsychiatry. 2016. PMID: 26740416
INTRODUCTION: Cognitive and functional compromise, as frequently observed in Alzheimer's disease (AD), hinders communication and social interactions. One consequence of this hindrance may be a feeling of loneliness. Moreover, emptiness and boredom, as …
INTRODUCTION: Cognitive and functional compromise, as frequently observed in Alzheimer's disease (AD), hinders communic …
Associations of Social Isolation and Loneliness With Later Dementia.
Shen C, Rolls ET, Cheng W, Kang J, Dong G, Xie C, Zhao XM, Sahakian BJ, Feng J. Shen C, et al. Neurology. 2022 Jul 11;99(2):e164-e175. doi: 10.1212/WNL.0000000000200583. Neurology. 2022. PMID: 35676089
METHODS: We utilized the UK Biobank cohort to establish Cox proportional hazard models with social isolation and loneliness as separate exposures. Demographic (sex, age, and ethnicity), socioeconomic (education level, household income, and Townsend deprivation index), biol …
METHODS: We utilized the UK Biobank cohort to establish Cox proportional hazard models with social isolation and loneliness as separa …
Loneliness could be a predictor for Alzheimer's disease.
[No authors listed] [No authors listed] Nurs Stand. 2016 Nov 23;31(13):17. doi: 10.7748/ns.31.13.17.s19. Nurs Stand. 2016. PMID: 27892212
Lonely people have an increased risk of developing Alzheimer's disease because they have high levels of the protein amyloid in the brain, suggest US researchers....
Lonely people have an increased risk of developing Alzheimer's disease because they have high levels of the protein amy …
Loneliness Increases the Risk of All-Cause Dementia and Alzheimer's Disease.
Sundström A, Adolfsson AN, Nordin M, Adolfsson R. Sundström A, et al. J Gerontol B Psychol Sci Soc Sci. 2020 Apr 16;75(5):919-926. doi: 10.1093/geronb/gbz139. J Gerontol B Psychol Sci Soc Sci. 2020. PMID: 31676909 Free PMC article.
OBJECTIVES: To examine the effect of perceived loneliness on the development of dementia (all-cause), Alzheimers disease (AD), and vascular dementia (VaD). ...These results underscore the importance of paying attention to subjective reports of loneliness …
OBJECTIVES: To examine the effect of perceived loneliness on the development of dementia (all-cause), Alzheimers disease …
Loneliness and risk of all-cause, Alzheimer's, vascular, and frontotemporal dementia: a prospective study of 492,322 individuals over 15 years.
Sutin AR, Luchetti M, Aschwanden D, Zhu X, Stephan Y, Terracciano A. Sutin AR, et al. Int Psychogeriatr. 2023 Jun;35(6):283-292. doi: 10.1017/S1041610222001028. Epub 2022 Dec 9. Int Psychogeriatr. 2023. PMID: 36482759 Free PMC article.
PARTICIPANTS: Participants were from the UK Biobank (N = 492,322). INTERVENTION: None. MEASUREMENTS: Loneliness was measured with a standard item. The diagnosis of dementia was derived from health and death records, which included all-cause dementia and the specific diagno …
PARTICIPANTS: Participants were from the UK Biobank (N = 492,322). INTERVENTION: None. MEASUREMENTS: Loneliness was measured with a s …
The Association between Social Engagement, Loneliness, and Risk of Dementia: A Systematic Review and Meta-Analysis.
Penninkilampi R, Casey AN, Singh MF, Brodaty H. Penninkilampi R, et al. J Alzheimers Dis. 2018;66(4):1619-1633. doi: 10.3233/JAD-180439. J Alzheimers Dis. 2018. PMID: 30452410
We included cohort and case-control studies examining the association between social engagement or loneliness and dementia risk, pooling data using a random-effects model. ...In long-term studies (10 years), good social engagement was modestly protective (RR = 0.88, 95% CI …
We included cohort and case-control studies examining the association between social engagement or loneliness and dementia risk, pool …
309 results