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Page 1
Luteolin, a flavonoid, as an anticancer agent: A review.
Imran M, Rauf A, Abu-Izneid T, Nadeem M, Shariati MA, Khan IA, Imran A, Orhan IE, Rizwan M, Atif M, Gondal TA, Mubarak MS. Imran M, et al. Biomed Pharmacother. 2019 Apr;112:108612. doi: 10.1016/j.biopha.2019.108612. Epub 2019 Feb 21. Biomed Pharmacother. 2019. PMID: 30798142 Free article. Review.
Many food-derived phytochemicals and their derivatives represent a cornucopia of new anti-cancer compounds. Luteolin (3,4,5,7-tetrahydroxy flavone) is a flavonoid found in different plants such as vegetables, medicinal herbs, and fruits. ...Accordingly, the present review …
Many food-derived phytochemicals and their derivatives represent a cornucopia of new anti-cancer compounds. Luteolin (3,4,5,7-tetrahy …
Can luteolin be a therapeutic molecule for both colon cancer and diabetes?
Ambasta RK, Gupta R, Kumar D, Bhattacharya S, Sarkar A, Kumar P. Ambasta RK, et al. Brief Funct Genomics. 2018 Jul 22;18(4):230-239. doi: 10.1093/bfgp/ely036. Brief Funct Genomics. 2018. PMID: 30462152 Review.
The search confirms that luteolin can be a remedial molecule for both cancer and diabetes via acting on variety of signaling pathway. Furthermore, we also intend to illustrate/compare the predicted and verified molecular modes of action of luteolin. Fluorescence in …
The search confirms that luteolin can be a remedial molecule for both cancer and diabetes via acting on variety of signaling pathway. …
Plant-derived bioactive compounds in colon cancer treatment: An updated review.
Esmeeta A, Adhikary S, Dharshnaa V, Swarnamughi P, Ummul Maqsummiya Z, Banerjee A, Pathak S, Duttaroy AK. Esmeeta A, et al. Biomed Pharmacother. 2022 Sep;153:113384. doi: 10.1016/j.biopha.2022.113384. Epub 2022 Jul 9. Biomed Pharmacother. 2022. PMID: 35820317 Free article. Review.
Colon cancer is the third most predominant cancer caused by genetic, environmental and nutritional factors. ...Medicinal plants contain many bioactive phytochemicals such as flavonoids, polyphenol compounds, caffeic acid, catechins, saponins, polysaccharides, triterpenoids
Colon cancer is the third most predominant cancer caused by genetic, environmental and nutritional factors. ...Medicinal plants conta
Luteolin alleviates inflammation and modulates gut microbiota in ulcerative colitis rats.
Li B, Du P, Du Y, Zhao D, Cai Y, Yang Q, Guo Z. Li B, et al. Life Sci. 2021 Mar 15;269:119008. doi: 10.1016/j.lfs.2020.119008. Epub 2021 Jan 9. Life Sci. 2021. PMID: 33434535 Free article.
In this study, we investigated the effects of luteolin on colonic structure and inflammation of dextran sulfate sodium (DSS)-induced rats using hematoxylin-eosin staining, immunohistochemistry and enzyme-linked immunosorbent assay and evaluated the effects of lut
In this study, we investigated the effects of luteolin on colonic structure and inflammation of dextran sulfate sodium (DSS)-i …
Luteolin exhibits synergistic therapeutic efficacy with erastin to induce ferroptosis in colon cancer cells through the HIC1-mediated inhibition of GPX4 expression.
Zheng Y, Li L, Chen H, Zheng Y, Tan X, Zhang G, Jiang R, Yu H, Lin S, Wei Y, Wang Y, Zhang R, Liu Z, Wu J. Zheng Y, et al. Free Radic Biol Med. 2023 Nov 1;208:530-544. doi: 10.1016/j.freeradbiomed.2023.09.014. Epub 2023 Sep 17. Free Radic Biol Med. 2023. PMID: 37717793
The results showed that combinative treatment of luteolin and erastin effectively inhibited the viability and proliferation of colon cancer cells. ...Mechanistically, luteolin in combination with erastin synergistically reduced the expression of glutathione p …
The results showed that combinative treatment of luteolin and erastin effectively inhibited the viability and proliferation of col
Luteolin Induces Apoptosis and Autophagy in HCT116 Colon Cancer Cells via p53-Dependent Pathway.
Yoo HS, Won SB, Kwon YH. Yoo HS, et al. Nutr Cancer. 2022;74(2):677-686. doi: 10.1080/01635581.2021.1903947. Epub 2021 Mar 24. Nutr Cancer. 2022. PMID: 33757400
Here, we investigated whether luteolin exhibits its anticancer effects by induction of apoptosis and autophagy in a p53-dependent manner in colon cancer cells. ...The expressions of proteins and mRNAs were measured by immunoblotting and reverse transcription polymer …
Here, we investigated whether luteolin exhibits its anticancer effects by induction of apoptosis and autophagy in a p53-dependent man …
Luteolin suppresses the growth of colon cancer cells by inhibiting the IL-6/STAT3 signaling pathway.
Jiang J, Zhu F, Zhang H, Sun T, Fu F, Chen X, Zhang Y. Jiang J, et al. J Gastrointest Oncol. 2022 Aug;13(4):1722-1732. doi: 10.21037/jgo-22-507. J Gastrointest Oncol. 2022. PMID: 36092354 Free PMC article.
This study aimed to discuss the potential of luteolin in the treatment of colon cancer, from the perspective of traditional Chinese medicine, with a particular focus on the tumor microenvironment. ...In addition, IL-6 promoted LPS-induced M1 polarization, while the …
This study aimed to discuss the potential of luteolin in the treatment of colon cancer, from the perspective of traditional Ch …
Combined Curcumin and Luteolin Synergistically Inhibit Colon Cancer Associated with Notch1 and TGF-beta Signaling Pathways in Cultured Cells and Xenograft Mice.
Aromokeye R, Si H. Aromokeye R, et al. Cancers (Basel). 2022 Jun 18;14(12):3001. doi: 10.3390/cancers14123001. Cancers (Basel). 2022. PMID: 35740666 Free PMC article.
This study aimed to select a combination of curcumin and luteolin, two phytochemicals from food, at lower concentrations with a higher inhibitory effect on colon cancer growth and investigate possible molecular mechanisms of this anti-colon cancer effect. ... …
This study aimed to select a combination of curcumin and luteolin, two phytochemicals from food, at lower concentrations with a highe …
Antitumor activity of luteolin in human colon cancer SW620 cells is mediated by the ERK/FOXO3a signaling pathway.
Potočnjak I, Šimić L, Gobin I, Vukelić I, Domitrović R. Potočnjak I, et al. Toxicol In Vitro. 2020 Aug;66:104852. doi: 10.1016/j.tiv.2020.104852. Epub 2020 Apr 5. Toxicol In Vitro. 2020. PMID: 32268164
The aim of this study was to investigate the mechanism of the anticancer activity of luteolin in metastatic human colon cancer SW620 cells. Luteolin dose-dependently reduced the viability and proliferation of SW620 cells and increased the expression of antiox …
The aim of this study was to investigate the mechanism of the anticancer activity of luteolin in metastatic human colon cancer …
Luteolin induces apoptotic cell death via antioxidant activity in human colon cancer cells.
Kang KA, Piao MJ, Ryu YS, Hyun YJ, Park JE, Shilnikova K, Zhen AX, Kang HK, Koh YS, Jeong YJ, Hyun JW. Kang KA, et al. Int J Oncol. 2017 Oct;51(4):1169-1178. doi: 10.3892/ijo.2017.4091. Epub 2017 Aug 2. Int J Oncol. 2017. PMID: 28791416
The present study determined whether luteolin induces HT-29 colon cancer cell death through an antioxidant effect such as the activation of antioxidant enzymes. Luteolin decreased cell viability in human colon cancer cells (HT-29), whereas it had no ef …
The present study determined whether luteolin induces HT-29 colon cancer cell death through an antioxidant effect such as the …
155 results