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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1972 2
1973 2
1974 5
1975 6
1976 11
1977 15
1978 5
1979 9
1980 11
1981 18
1982 6
1983 6
1984 7
1985 16
1986 3
1987 10
1988 6
1989 6
1990 6
1991 4
1992 9
1993 10
1994 16
1995 7
1996 10
1997 7
1998 12
1999 10
2000 17
2001 10
2002 6
2003 11
2004 17
2005 16
2006 15
2007 15
2008 16
2009 17
2010 25
2011 21
2012 19
2013 28
2014 23
2015 32
2016 27
2017 26
2018 46
2019 43
2020 39
2021 63
2022 40
2023 32
2024 13

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769 results

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Page 1
Lysyl hydroxylase LH1 promotes confined migration and metastasis of cancer cells by stabilizing Septin2 to enhance actin network.
Yang Z, Zhou L, Si T, Chen S, Liu C, Ng KK, Wang Z, Chen Z, Qiu C, Liu G, Wang Q, Zhou X, Zhang L, Yao Z, He S, Yang M, Zhou Z. Yang Z, et al. Mol Cancer. 2023 Jan 31;22(1):21. doi: 10.1186/s12943-023-01727-9. Mol Cancer. 2023. PMID: 36721170 Free PMC article.
Immunofluorescent staining, FRET, RT-PCR, Western blotting, FRAP, CCK-8, transwell cell migration, wound healing, orthotopic liver injection mouse model and in vivo imaging were used to evaluate the target expression and cellular phenotype. RESULTS: Lysyl hydroxylase …
Immunofluorescent staining, FRET, RT-PCR, Western blotting, FRAP, CCK-8, transwell cell migration, wound healing, orthotopic liver injection …
Lysyl hydroxylase 1 (LH1) deficiency promotes angiotensin II (Ang II)-induced dissecting abdominal aortic aneurysm.
Li H, Xu H, Wen H, Wang H, Zhao R, Sun Y, Bai C, Ping J, Song L, Luo M, Chen J. Li H, et al. Theranostics. 2021 Sep 21;11(19):9587-9604. doi: 10.7150/thno.65277. eCollection 2021. Theranostics. 2021. PMID: 34646388 Free PMC article.
Rationale: The progressive disruption of extracellular matrix (ECM) proteins, particularly early elastin fragmentation followed by abnormalities in collagen fibril organization, are key pathological processes that contribute to dissecting abdominal aortic aneurysm (AAA) pathogene …
Rationale: The progressive disruption of extracellular matrix (ECM) proteins, particularly early elastin fragmentation followed by abnormali …
Lysyl hydroxylase 2 deficiency promotes filopodia formation and fibroblast migration.
Nozaki R, Kasamatsu A, Moss J, Uzawa K. Nozaki R, et al. Biochem Biophys Res Commun. 2022 Jan 8;587:146-152. doi: 10.1016/j.bbrc.2021.11.100. Epub 2021 Nov 30. Biochem Biophys Res Commun. 2022. PMID: 34875533 Free PMC article.
Lysyl hydroxylase 2 (LH2) regulates intermolecular cross-linking of collagen molecules. ...
Lysyl hydroxylase 2 (LH2) regulates intermolecular cross-linking of collagen molecules. ...
Lysyl hydroxylase 2 mediated collagen post-translational modifications and functional outcomes.
Terajima M, Taga Y, Nakamura T, Guo HF, Kayashima Y, Maeda-Smithies N, Parag-Sharma K, Kim JS, Amelio AL, Mizuno K, Kurie JM, Yamauchi M. Terajima M, et al. Sci Rep. 2022 Aug 22;12(1):14256. doi: 10.1038/s41598-022-18165-0. Sci Rep. 2022. PMID: 35995931 Free PMC article.
Lysyl hydroxylase 2 (LH2) is a member of LH family that catalyzes the hydroxylation of lysine (Lys) residues on collagen, and this particular isozyme has been implicated in various diseases. ...
Lysyl hydroxylase 2 (LH2) is a member of LH family that catalyzes the hydroxylation of lysine (Lys) residues on collagen, and …
Collagen cross-linking mediated by lysyl hydroxylase 2: an enzymatic battlefield to combat fibrosis.
Piersma B, Bank RA. Piersma B, et al. Essays Biochem. 2019 Sep 13;63(3):377-387. doi: 10.1042/EBC20180051. Print 2019 Sep 13. Essays Biochem. 2019. PMID: 31324706 Review.
Hydroxyallysine is derived from a hydroxylysine in the telopeptides of collagen. The expression of lysyl hydroxylase (LH) 2 (LH2), the enzyme responsible for the formation of telopeptidyl hydroxylysine, is universally up-regulated in fibrosis. ...
Hydroxyallysine is derived from a hydroxylysine in the telopeptides of collagen. The expression of lysyl hydroxylase (LH) 2 (L …
Lysyl hydroxylase 3-mediated post-translational modifications are required for proper biosynthesis of collagen alpha1alpha1alpha2(IV).
Ishikawa Y, Taga Y, Coste T, Tufa SF, Keene DR, Mizuno K, Tournier-Lasserve E, Gould DB. Ishikawa Y, et al. J Biol Chem. 2022 Dec;298(12):102713. doi: 10.1016/j.jbc.2022.102713. Epub 2022 Nov 17. J Biol Chem. 2022. PMID: 36403858 Free PMC article.
Pathogenic variants in genes encoding collagens cause connective tissue disorders, including osteogenesis imperfecta, Ehlers-Danlos syndrome, and Gould syndrome (caused by mutations in COL4A1 and COL4A2), and pathogenic variants in genes encoding proteins required for collagen bi …
Pathogenic variants in genes encoding collagens cause connective tissue disorders, including osteogenesis imperfecta, Ehlers-Danlos syndrome …
Lysyl hydroxylase 2-induced collagen cross-link switching promotes metastasis in head and neck squamous cell carcinomas.
Sato K, Parag-Sharma K, Terajima M, Musicant AM, Murphy RM, Ramsey MR, Hibi H, Yamauchi M, Amelio AL. Sato K, et al. Neoplasia. 2021 Jun;23(6):594-606. doi: 10.1016/j.neo.2021.05.014. Epub 2021 Jun 6. Neoplasia. 2021. PMID: 34107376 Free PMC article.
HNSCC patient prognosis is closely related to the occurrence of tumor metastases, and collagen within the tumor microenvironment (TME) plays a key role in this process. Lysyl hydroxylase 2 (LH2), encoded by the Procollagen-Lysine,2-Oxoglutara …
HNSCC patient prognosis is closely related to the occurrence of tumor metastases, and collagen within the tumor microenvironment (TME) plays …
Lysyl hydroxylase 3 is required for normal lens capsule formation and maintenance of lens epithelium integrity and fate.
Taler K, Weiss O, Rotem-Bamberger S, Rubinstein AM, Seritrakul P, Gross JM, Inbal A. Taler K, et al. Dev Biol. 2020 Feb 15;458(2):177-188. doi: 10.1016/j.ydbio.2019.10.020. Epub 2019 Oct 24. Dev Biol. 2020. PMID: 31669351 Free article.
Here we describe a zebrafish mutation causing the embryonic lens epithelium to generate cellular masses comprising partially differentiated lens fiber cells. We identify the mutant gene as plod3, which encodes for Lysyl hydroxylase 3 (Lh3), an enzyme essential for m …
Here we describe a zebrafish mutation causing the embryonic lens epithelium to generate cellular masses comprising partially differentiated …
Expanding the lysyl hydroxylase toolbox: new insights into the localization and activities of lysyl hydroxylase 3 (LH3).
Myllylä R, Wang C, Heikkinen J, Juffer A, Lampela O, Risteli M, Ruotsalainen H, Salo A, Sipilä L. Myllylä R, et al. J Cell Physiol. 2007 Aug;212(2):323-9. doi: 10.1002/jcp.21036. J Cell Physiol. 2007. PMID: 17516569 Review.
Since the last published reviews, significant new data have accumulated regarding these modifications. One of the lysyl hydroxylase isoforms, lysyl hydroxylase 3 (LH3), has been shown to possess three catalytic activities required sequentially to produ …
Since the last published reviews, significant new data have accumulated regarding these modifications. One of the lysyl hydroxylas …
Recombinant expression of hydroxylated human collagen in Escherichia coli.
Rutschmann C, Baumann S, Cabalzar J, Luther KB, Hennet T. Rutschmann C, et al. Appl Microbiol Biotechnol. 2014 May;98(10):4445-55. doi: 10.1007/s00253-013-5447-z. Epub 2013 Dec 21. Appl Microbiol Biotechnol. 2014. PMID: 24362857 Free article.
The characterization of new prolyl and lysyl hydroxylase genes encoded by the giant virus mimivirus reveals a method for production of hydroxylated collagen. ...The respective levels of prolyl and lysyl hydroxylation reaching 25 % and 26 % were similar to the …
The characterization of new prolyl and lysyl hydroxylase genes encoded by the giant virus mimivirus reveals a method for produ …
769 results

Searches related to "lysyl hydroxylase"