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A Magtein(), Magnesium L-Threonate, -Based Formula Improves Brain Cognitive Functions in Healthy Chinese Adults.
Zhang C, Hu Q, Li S, Dai F, Qian W, Hewlings S, Yan T, Wang Y. Zhang C, et al. Nutrients. 2022 Dec 8;14(24):5235. doi: 10.3390/nu14245235. Nutrients. 2022. PMID: 36558392 Free PMC article. Clinical Trial.
Magnesium supplements mostly have low bioavailability, except magnesium L-threonate. In 2010, a novel magnesium compound, magnesium L-threonate (Magtein()) was identified and was shown to raise the magnesium levels in …
Magnesium supplements mostly have low bioavailability, except magnesium L-threonate. In 2010, a novel magnesi …
Magnesium-L-threonate treats Alzheimer's disease by modulating the microbiota-gut-brain axis.
Liao W, Wei J, Liu C, Luo H, Ruan Y, Mai Y, Yu Q, Cao Z, Xu J, Zheng D, Sheng Z, Zhou X, Liu J. Liao W, et al. Neural Regen Res. 2024 Oct 1;19(10):2281-2289. doi: 10.4103/1673-5374.391310. Epub 2023 Dec 21. Neural Regen Res. 2024. PMID: 38488562 Free PMC article.
However, the effects of magnesium-L-threonate on the gut microbiota in Alzheimer's disease remain unknown. ...We also found that differential metabolites in the magnesium-L-threonate-regulated serum were enriched in various pathways assoc …
However, the effects of magnesium-L-threonate on the gut microbiota in Alzheimer's disease remain unknown. ...We also f …
Magnesium-L-threonate alleviate colonic inflammation and memory impairment in chronic-plus-binge alcohol feeding mice.
Liu C, Cheng Y, Guo Y, Qian H. Liu C, et al. Brain Res Bull. 2021 Sep;174:184-193. doi: 10.1016/j.brainresbull.2021.06.009. Epub 2021 Jun 16. Brain Res Bull. 2021. PMID: 34144203
Magnesium-l-threonate (MgT) is considered a food supplement. Alcohol-mediated diseases (AMD) are accompanied by inflammation and memory impairment. ...
Magnesium-l-threonate (MgT) is considered a food supplement. Alcohol-mediated diseases (AMD) are accompanied by inflamm …
Oral application of magnesium-L-threonate enhances analgesia and reduces the dosage of opioids needed in advanced cancer patients-A randomized, double-blind, placebo-controlled trial.
Wu S, Jin T, Ma B, Ji Y, Huang X, Wang P, Liu X, Krylov BV, Liu X, Ma K. Wu S, et al. Cancer Med. 2023 Feb;12(4):4343-4351. doi: 10.1002/cam4.4922. Epub 2023 Jan 26. Cancer Med. 2023. PMID: 36703238 Free PMC article. Clinical Trial.
PURPOSE: To investigate the effects of oral administration of magnesium-L-threonate, a novel magnesium compound, on the analgesic effect of opioids in patients with advanced cancer. ...
PURPOSE: To investigate the effects of oral administration of magnesium-L-threonate, a novel magnesium compound, …
Role of magnesium-L-Threonate in alleviating skin/muscle incision and retraction induced mechanical allodynia and anxiodepressive-like behaviors in male rats.
Chen Y, Zhang Y, Lin W, Tang Y, Chen L, Gao Y, Gao G, Luo X, Chen A, Lin C. Chen Y, et al. Brain Res. 2023 Oct 15;1817:148476. doi: 10.1016/j.brainres.2023.148476. Epub 2023 Jul 3. Brain Res. 2023. PMID: 37406874
However, its underlying mechanism remains unclear. Emerging studies indicate that magnesium deficiency is associated with neurological diseases, and magnesium supplement confers protection under these disease conditions. In this study, we examined the role and mecha …
However, its underlying mechanism remains unclear. Emerging studies indicate that magnesium deficiency is associated with neurologica …
Magnesium-L-threonate exhibited a neuroprotective effect against oxidative stress damage in HT22 cells and Alzheimer's disease mouse model.
Xiong Y, Ruan YT, Zhao J, Yang YW, Chen LP, Mai YR, Yu Q, Cao ZY, Liu FF, Liao W, Liu J. Xiong Y, et al. World J Psychiatry. 2022 Mar 19;12(3):410-424. doi: 10.5498/wjp.v12.i3.410. eCollection 2022 Mar 19. World J Psychiatry. 2022. PMID: 35433327 Free PMC article.
BACKGROUND: Oxidative stress results in the production of excess reactive oxygen species (ROS) and triggers hippocampal neuronal damage as well as occupies a key role in the pathological mechanisms of neurodegenerative disorders such as Alzheimer's disease (AD). A recent study co …
BACKGROUND: Oxidative stress results in the production of excess reactive oxygen species (ROS) and triggers hippocampal neuronal damage as w …
Neuroprotective effects of magnesium L-threonate in a hypoxic zebrafish model.
Kim YS, Won YJ, Lim BG, Min TJ, Kim YH, Lee IO. Kim YS, et al. BMC Neurosci. 2020 Jun 26;21(1):29. doi: 10.1186/s12868-020-00580-6. BMC Neurosci. 2020. PMID: 32590943 Free PMC article.
BACKGROUND: Hypoxia inhibits the uptake of glutamate (a major neurotransmitter in the brain closely related to cognitive function) into brain cells, and the initial response of cells to cortical hypoxia depends on glutamate. Previous studies have suggested that magnesium m …
BACKGROUND: Hypoxia inhibits the uptake of glutamate (a major neurotransmitter in the brain closely related to cognitive function) into brai …
Treatment Of Magnesium-L-Threonate Elevates The Magnesium Level In The Cerebrospinal Fluid And Attenuates Motor Deficits And Dopamine Neuron Loss In A Mouse Model Of Parkinson's disease.
Shen Y, Dai L, Tian H, Xu R, Li F, Li Z, Zhou J, Wang L, Dong J, Sun L. Shen Y, et al. Neuropsychiatr Dis Treat. 2019 Nov 11;15:3143-3153. doi: 10.2147/NDT.S230688. eCollection 2019. Neuropsychiatr Dis Treat. 2019. PMID: 31806980 Free PMC article.
PURPOSE: Epidemiology research has demonstrated that magnesium (Mg) deficiency is associated with a high incidence of Parkinson's disease (PD). It is known that the systemic administration of MgSO(4) is not able to elevate the Mg concentration in cerebrospinal fluid (CSF). …
PURPOSE: Epidemiology research has demonstrated that magnesium (Mg) deficiency is associated with a high incidence of Parkinson's dis …
Oral Application of Magnesium-L-Threonate Attenuates Vincristine-induced Allodynia and Hyperalgesia by Normalization of Tumor Necrosis Factor-alpha/Nuclear Factor-kappaB Signaling.
Xu T, Li D, Zhou X, Ouyang HD, Zhou LJ, Zhou H, Zhang HM, Wei XH, Liu G, Liu XG. Xu T, et al. Anesthesiology. 2017 Jun;126(6):1151-1168. doi: 10.1097/ALN.0000000000001601. Anesthesiology. 2017. PMID: 28306698 Free article.
Reducing Mg activated tumor necrosis factor-alpha/nuclear factor-kappaB signaling in cultured dorsal root ganglion neurons. Oral application of magnesium-L-threonate prevented magnesium deficiency and attenuated both activation of tumor necrosis factor …
Reducing Mg activated tumor necrosis factor-alpha/nuclear factor-kappaB signaling in cultured dorsal root ganglion neurons. Oral application …
Chronic Oral Administration of Magnesium-L-Threonate Prevents Oxaliplatin-Induced Memory and Emotional Deficits by Normalization of TNF-alpha/NF-kappaB Signaling in Rats.
Zhou X, Huang Z, Zhang J, Chen JL, Yao PW, Mai CL, Mai JZ, Zhang H, Liu XG. Zhou X, et al. Neurosci Bull. 2021 Jan;37(1):55-69. doi: 10.1007/s12264-020-00563-x. Epub 2020 Aug 28. Neurosci Bull. 2021. PMID: 32857294 Free PMC article.
The OXA-induced behavioral and synaptic changes were prevented by chronic oral administration of magnesium-L-threonate (L-TAMS, 604 mg/kg per day, from 2 days before until the end of experiments). ...
The OXA-induced behavioral and synaptic changes were prevented by chronic oral administration of magnesium-L-threonate …
38 results