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Showing results for magnolia
Search for magnolax instead (1 results)
The MAGNOLIA Trial: Zanubrutinib, a Next-Generation Bruton Tyrosine Kinase Inhibitor, Demonstrates Safety and Efficacy in Relapsed/Refractory Marginal Zone Lymphoma.
Opat S, Tedeschi A, Linton K, McKay P, Hu B, Chan H, Jin J, Sobieraj-Teague M, Zinzani PL, Coleman M, Thieblemont C, Browett P, Ke X, Sun M, Marcus R, Portell CA, Ardeshna K, Bijou F, Walker P, Hawkes EA, Mapp S, Ho SJ, Talaulikar D, Zhou KS, Co M, Li X, Zhou W, Cappellini M, Tankersley C, Huang J, Trotman J. Opat S, et al. Clin Cancer Res. 2021 Dec 1;27(23):6323-6332. doi: 10.1158/1078-0432.CCR-21-1704. Epub 2021 Sep 15. Clin Cancer Res. 2021. PMID: 34526366 Free PMC article.
PATIENTS AND METHODS: Patients with R/R MZL were enrolled in the phase II MAGNOLIA (BGB-3111-214) study. The primary endpoint was overall response rate (ORR) as determined by an independent review committee (IRC) based on the Lugano 2014 classification. ...
PATIENTS AND METHODS: Patients with R/R MZL were enrolled in the phase II MAGNOLIA (BGB-3111-214) study. The primary endpoint was ove …
Safety and efficacy of zanubrutinib in relapsed/refractory marginal zone lymphoma: final analysis of the MAGNOLIA study.
Opat S, Tedeschi A, Hu B, Linton KM, McKay P, Leitch S, Coleman M, Zinzani PL, Jin J, Sun M, Sobieraj-Teague M, Browett P, Ke X, Thieblemont C, Ardeshna K, Bijou F, Walker P, Hawkes EA, Ho SJ, Zhou K, Liang Z, Xu J, Tankersley C, Delarue R, Co M, Trotman J. Opat S, et al. Blood Adv. 2023 Nov 28;7(22):6801-6811. doi: 10.1182/bloodadvances.2023010668. Blood Adv. 2023. PMID: 37682792 Free PMC article. Clinical Trial.
Presented here, is the final analysis of MAGNOLIA, performed to characterize the durability of response and longer-term safety and tolerability. ...Neutropenia (n = 8 [11.8%]) was the most common grade 3 adverse event. In this final analysis of MAGNOLIA, zanubrutini …
Presented here, is the final analysis of MAGNOLIA, performed to characterize the durability of response and longer-term safety and to …
Effect of Coptis chinensis franch and Magnolia officinalis on intestinal flora and intestinal barrier in a TNBS-induced ulcerative colitis rats model.
Xie Q, Li H, Ma R, Ren M, Li Y, Li J, Chen H, Chen Z, Gong D, Wang J. Xie Q, et al. Phytomedicine. 2022 Mar;97:153927. doi: 10.1016/j.phymed.2022.153927. Epub 2022 Jan 5. Phytomedicine. 2022. PMID: 35030387
BACKGROUND: In folk medicine Coptis chinensis Franch (Huanglian in Chinese, HL) and Magnoliae officinalis (Houpo, HP) have been used to treat gastrointestinal disorders over hundreds of years, such as ulcers and inflammation. ...In addition, HL+HP could also inhibit the in …
BACKGROUND: In folk medicine Coptis chinensis Franch (Huanglian in Chinese, HL) and Magnoliae officinalis (Houpo, HP) have been used …
The Potential of Magnolia spp. in the Production of Alternative Pest Control Substances.
Hernandez-Rocha JV, Vásquez-Morales SG. Hernandez-Rocha JV, et al. Molecules. 2023 Jun 9;28(12):4681. doi: 10.3390/molecules28124681. Molecules. 2023. PMID: 37375236 Free PMC article. Review.
From 11 Magnolia species, 277 natural compounds were obtained, 68.7% of which were terpenoids, phenolic compounds, and alkaloids. Finally, the importance of a correct management of Magnolia species to ensure their sustainable use and conservation is stressed....
From 11 Magnolia species, 277 natural compounds were obtained, 68.7% of which were terpenoids, phenolic compounds, and alkaloids. Fin …
Magnolol: A Neolignan from the Magnolia Family for the Prevention and Treatment of Cancer.
Ranaware AM, Banik K, Deshpande V, Padmavathi G, Roy NK, Sethi G, Fan L, Kumar AP, Kunnumakkara AB. Ranaware AM, et al. Int J Mol Sci. 2018 Aug 10;19(8):2362. doi: 10.3390/ijms19082362. Int J Mol Sci. 2018. PMID: 30103472 Free PMC article. Review.
Magnolol is a hydroxylated biphenyl isolated from the root and stem bark of Magnolia tree. Magnolol can efficiently prevent or inhibit the growth of various cancers originating from different organs such as brain, breast, cervical, colon, liver, lung, prostate, skin, etc. …
Magnolol is a hydroxylated biphenyl isolated from the root and stem bark of Magnolia tree. Magnolol can efficiently prevent or inhibi …
Safety and Toxicology of Magnolol and Honokiol.
Sarrica A, Kirika N, Romeo M, Salmona M, Diomede L. Sarrica A, et al. Planta Med. 2018 Nov;84(16):1151-1164. doi: 10.1055/a-0642-1966. Epub 2018 Jun 20. Planta Med. 2018. PMID: 29925102 Free article. Review.
Magnolia officinalis and Magnolia obovata bark extracts have been used for thousands of years in Chinese and Japanese traditional medicines and are still widely employed as herbal preparations for their sedative, antioxidant, anti-inflammatory, antibiotic, and antis
Magnolia officinalis and Magnolia obovata bark extracts have been used for thousands of years in Chinese and Japanese traditio
Extracts of Magnolia Species-Induced Prevention of Diabetic Complications: A Brief Review.
Zhao X, Li F, Sun W, Gao L, Kim KS, Kim KT, Cai L, Zhang Z, Zheng Y. Zhao X, et al. Int J Mol Sci. 2016 Sep 24;17(10):1629. doi: 10.3390/ijms17101629. Int J Mol Sci. 2016. PMID: 27669240 Free PMC article. Review.
Several studies have established the anti-inflammatory and oxidative roles of bioactive constituents in Magnolia bark, which has been widely used in the traditional herbal medicines in Chinese society. These findings have attracted various scientists to investigate the eff …
Several studies have established the anti-inflammatory and oxidative roles of bioactive constituents in Magnolia bark, which has been …
Cardiovascular Modulating Effects of Magnolol and Honokiol, Two Polyphenolic Compounds from Traditional Chinese Medicine-Magnolia Officinalis.
Yuan Y, Zhou X, Wang Y, Wang Y, Teng X, Wang S. Yuan Y, et al. Curr Drug Targets. 2020;21(6):559-572. doi: 10.2174/1389450120666191024175727. Curr Drug Targets. 2020. PMID: 31749425 Review.
Honokiol and its isomer magnolol are poly-phenolic compounds isolated from the Magnolia officinalis that exert cardiovascular modulating effects via a variety of mechanisms. ...
Honokiol and its isomer magnolol are poly-phenolic compounds isolated from the Magnolia officinalis that exert cardiovascular modulat …
Compound from Magnolia officinalis Ameliorates White Matter Injury by Promoting Oligodendrocyte Maturation in Chronic Cerebral Ischemia Models.
Zhang Z, Shu X, Cao Q, Xu L, Wang Z, Li C, Xia S, Shao P, Bao X, Sun L, Xu Y, Xu Y. Zhang Z, et al. Neurosci Bull. 2023 Oct;39(10):1497-1511. doi: 10.1007/s12264-023-01068-z. Epub 2023 Jun 9. Neurosci Bull. 2023. PMID: 37291477 Free PMC article.
In this study, we found that honokiol and magnolol, two compounds derived from Magnolia officinalis, significantly facilitated the differentiation of primary oligodendrocyte precursor cells (OPCs) into mature oligodendrocytes, with a more prominent effect of the former com …
In this study, we found that honokiol and magnolol, two compounds derived from Magnolia officinalis, significantly facilitated the di …
Therapeutic applications of compounds in the Magnolia family.
Lee YJ, Lee YM, Lee CK, Jung JK, Han SB, Hong JT. Lee YJ, et al. Pharmacol Ther. 2011 May;130(2):157-76. doi: 10.1016/j.pharmthera.2011.01.010. Epub 2011 Jan 26. Pharmacol Ther. 2011. PMID: 21277893 Review.
The bark and/or seed cones of the Magnolia tree have been used in traditional herbal medicines in Korea, China and Japan. ...The aim of this study was to review a variety of experimental and clinical reports and, describe the effectiveness, toxicities and pharmacokinetics, …
The bark and/or seed cones of the Magnolia tree have been used in traditional herbal medicines in Korea, China and Japan. ...The aim …
3,828 results