Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 1
1971 1
1972 1
1975 1
1978 1
1980 1
1982 2
1986 1
1987 1
1988 1
1990 1
1991 1
1993 1
1995 1
1996 3
1997 2
2000 2
2001 2
2002 3
2006 2
2007 1
2011 1
2012 2
2014 1
2015 2
2016 1
2017 1
2018 1
2019 3
2020 4
2021 1
2022 2
2023 1
2024 1

Text availability

Article attribute

Article type

Publication date

Search Results

47 results

Results by year

Filters applied: . Clear all
Page 1
Showing results for mercaptopurine native
Your search for mercaptopurin-nativ retrieved no results
Long-term outcomes of patients with type 1 or 2 autoimmune hepatitis presenting in childhood.
Maggiore G, Bernard O, Mosca A, Ballot E, Johanet C, Jacquemin E. Maggiore G, et al. J Hepatol. 2023 May;78(5):979-988. doi: 10.1016/j.jhep.2023.01.013. Epub 2023 Jan 25. J Hepatol. 2023. PMID: 36708813
Liver transplantation was performed in 23 patients at a median age of 21 years. The 30-year probabilities of overall and native liver survival were 81% and 61%, respectively. No differences were observed between type 1 and 2 hepatitis for any of the component parts of outc …
Liver transplantation was performed in 23 patients at a median age of 21 years. The 30-year probabilities of overall and native liver …
Comprehensive analysis of dose intensity of acute lymphoblastic leukemia chemotherapy.
Karol SE, Pei D, Smith CA, Liu Y, Yang W, Kornegay NM, Panetta JC, Crews KR, Cheng C, Finch ER, Inaba H, Metzger ML, Rubnitz JE, Ribeiro RC, Gruber TA, Yang JJ, Evans WE, Jeha S, Pui CH, Relling MV. Karol SE, et al. Haematologica. 2022 Feb 1;107(2):371-380. doi: 10.3324/haematol.2021.278411. Haematologica. 2022. PMID: 34196166 Free PMC article.
The only dose intensity measure predicting a higher risk of relapse on both studies was higher mercaptopurine dose intensity, but this did not reach statistical significance (P=0.03 T15; P=0.07 T16). In these intensive multiagent trials, higher dosages of asparaginase comp …
The only dose intensity measure predicting a higher risk of relapse on both studies was higher mercaptopurine dose intensity, but thi …
Reduced vs. standard dose native E. coli-asparaginase therapy in childhood acute lymphoblastic leukemia: long-term results of the randomized trial Moscow-Berlin 2002.
Karachunskiy A, Tallen G, Roumiantseva J, Lagoiko S, Chervova A, von Stackelberg A, Aleinikova O, Bydanov O, Bajdun L, Nasedkina T, Korepanova N, Kuznetsov S, Novichkova G, Goroshkova M, Litvinov D, Myakova N, Ponomareva N, Inyushkina E, Kondratchik K, Abugova J, Fechina L, Arakaev O, Karelin A, Lebedev V, Judina N, Scharapova G, Spichak I, Shamardina A, Ryskal O, Shapochnik A, Rumjanzew A, Boos J, Henze G; ALL-MB study group. Karachunskiy A, et al. J Cancer Res Clin Oncol. 2019 Apr;145(4):1001-1012. doi: 10.1007/s00432-019-02854-x. Epub 2019 Mar 6. J Cancer Res Clin Oncol. 2019. PMID: 30840197 Free PMC article. Clinical Trial.
One major component of this regimen included a total of 18 doses of weekly intramuscular (IM) native Escherichia coli-derived asparaginase (E. coli-ASP) at 10000 U/m(2) during three consolidation courses. ...
One major component of this regimen included a total of 18 doses of weekly intramuscular (IM) native Escherichia coli-derived asparag …
Pharmacogenomics of thiopurines: distribution of TPMT and NUDT15 polymorphisms in the Brazilian Amazon.
Ferreira GMA, Ribeiro Elias AB, Nascimento J, Monteiro WM, Melo GC, Baia-da-Silva DC, Lacerda MVG, Suarez-Kurtz G. Ferreira GMA, et al. Pharmacogenet Genomics. 2020 Oct;30(8):184-189. doi: 10.1097/FPC.0000000000000411. Pharmacogenet Genomics. 2020. PMID: 32453263
The average proportion of Native and European ancestry differed greatly and significantly between self-declared Amerindians and non-Amerindians, although extensive admixture in both groups was evident. Native ancestry was not significantly associated with the freque …
The average proportion of Native and European ancestry differed greatly and significantly between self-declared Amerindians and non-A …
Biochemical Characterization of the Methylmercaptopropionate:Cob(I)alamin Methyltransferase from Methanosarcina acetivorans.
Fu H, Goettge MN, Metcalf WW. Fu H, et al. J Bacteriol. 2019 May 22;201(12):e00130-19. doi: 10.1128/JB.00130-19. Print 2019 Jun 15. J Bacteriol. 2019. PMID: 30936368 Free PMC article.
To test this, MtpA was purified after overexpression in its native host and characterized biochemically. MtpA catalyzes a robust methyl transfer reaction using free methylcob(III)alamin as the donor and mercaptopropionate (MPA) as the acceptor, with k(cat) of 0.315 s(-1) a …
To test this, MtpA was purified after overexpression in its native host and characterized biochemically. MtpA catalyzes a robust meth …
Pharmacogeomic implications of population diversity in Latin America: TPMT and NUDT15 polymorphisms and thiopurine dosing.
Suarez-Kurtz G, Araújo GS, de Sousa SJ. Suarez-Kurtz G, et al. Pharmacogenet Genomics. 2020 Jan;30(1):1-4. doi: 10.1097/FPC.0000000000000388. Pharmacogenet Genomics. 2020. PMID: 31651720
Significant differences were observed in the distribution of TPMT and NUDT15 haplotypes (star alleles) between individuals with predominant (>70%) European versus Native ancestry. The largest difference is related to NUDT15 rs116855232. ...These findings may be relevant …
Significant differences were observed in the distribution of TPMT and NUDT15 haplotypes (star alleles) between individuals with predominant …
[Primary CNS lymphoma in azathioprine therapy for autoimmune diseases: review of the literature and case report].
Kästner F, Paulus W, Deckert M, Schlegel P, Evers S, Husstedt IW. Kästner F, et al. Nervenarzt. 2007 Apr;78(4):451-6. doi: 10.1007/s00115-007-2255-7. Nervenarzt. 2007. PMID: 17375274 Review. German.
Prophylactic therapy with azathioprine over 9 months was stopped after the development of listeria meningitis which was treated successfully with antibiotics. At this time native CCT was normal. Three months later the patient developed an epileptic seizure and multiple cer …
Prophylactic therapy with azathioprine over 9 months was stopped after the development of listeria meningitis which was treated successfully …
Genotyping NUDT15*3 rs1166855232 reveals higher frequency of potential adverse effects of thiopurines in Natives and Mestizos from Mexico.
Texis T, Guzmán-Cruz C, Rodríguez-Dorantes M, Sánchez-García S, Mino-León D, Gonzalez-Covarrubias V. Texis T, et al. Pharmacol Rep. 2022 Feb;74(1):257-262. doi: 10.1007/s43440-021-00287-3. Epub 2021 Jun 6. Pharmacol Rep. 2022. PMID: 34091879
METHODS: Fifteen NUDT15 and TPMT variants were retrieved for 1270 Mestizos and 20 Natives genotyped from previous studies using the GSA-Illumina microarray. ...RESULTS: We report relevant populations differences in actionable TPMT*3B and NUDT15 rs116855232 as the allele fr …
METHODS: Fifteen NUDT15 and TPMT variants were retrieved for 1270 Mestizos and 20 Natives genotyped from previous studies using the G …
Identification of NUDT15 gene variants in Amazonian Amerindians and admixed individuals from northern Brazil.
Rodrigues JCG, Souza TP, Pastana LF, Ribeiro Dos Santos AM, Fernandes MR, Pinto P, Wanderley AV, Souza SJ, Kroll JE, Pereira AL, Magalhães L, Mercês LRD, Vidal AF, Vinasco-Sandoval T, Cavalcante GC, Guerreiro JF, Assumpção PP, Ribeiro-Dos-Santos Â, Santos S, Santos NPCD. Rodrigues JCG, et al. PLoS One. 2020 Apr 15;15(4):e0231651. doi: 10.1371/journal.pone.0231651. eCollection 2020. PLoS One. 2020. PMID: 32294118 Free PMC article.
Azathioprine metabolite measurements are not useful in following treatment of autoimmune hepatitis in Alaska Native and other non-Caucasian people.
Ferucci ED, Hurlburt KJ, Mayo MJ, Livingston S, Deubner H, Gove J, Plotnik J, McMahon BJ. Ferucci ED, et al. Can J Gastroenterol. 2011 Jan;25(1):21-7. doi: 10.1155/2011/137476. Can J Gastroenterol. 2011. PMID: 21258664 Free PMC article.
OBJECTIVE: To evaluate the association between TPMT genotype and enzyme activity, and the impact of TPMT enzyme activity on levels of azathioprine metabolites and leukopenia to assess the clinical utility of monitoring azathioprine metabolites in Alaska Native and other no …
OBJECTIVE: To evaluate the association between TPMT genotype and enzyme activity, and the impact of TPMT enzyme activity on levels of azathi …
47 results