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Showing results for merosin
Your search for merosan retrieved no results
Merosin/laminin-2 and muscular dystrophy.
Wewer UM, Engvall E. Wewer UM, et al. Neuromuscul Disord. 1996 Dec;6(6):409-18. doi: 10.1016/s0960-8966(96)00384-7. Neuromuscul Disord. 1996. PMID: 9027848 Review.
The particular importance of laminins for the formation and stability of cell adhesion complexes is highlighted in severe inherited diseases of muscle and skin. Merosin is the collective name for laminins that share a common subunit, the laminin alpha 2 chain. Me …
The particular importance of laminins for the formation and stability of cell adhesion complexes is highlighted in severe inherited diseases …
Merosin and congenital muscular dystrophy.
Miyagoe-Suzuki Y, Nakagawa M, Takeda S. Miyagoe-Suzuki Y, et al. Microsc Res Tech. 2000 Feb 1-15;48(3-4):181-91. doi: 10.1002/(SICI)1097-0029(20000201/15)48:3/4<181::AID-JEMT6>3.0.CO;2-Q. Microsc Res Tech. 2000. PMID: 10679965 Review.
Merosin (also called as Laminin-2) is an isoform of laminin comprised of the alpha2, beta1 and gamma1 chains. In European populations, half of the patients with classical congenital muscular dystrophy have mutations of the LAMA2 gene (6q22-23) and present red …
Merosin (also called as Laminin-2) is an isoform of laminin comprised of the alpha2, beta1 and gamma1 chains. In Europe …
Merosin (laminin-2) localization in basal lamina of normal skeletal muscle fibers and changes in plasma membrane of merosin-deficient skeletal muscle fibers.
Shibuya S, Wakayama Y, Inoue M, Kojima H, Oniki H. Shibuya S, et al. Med Electron Microsc. 2003 Dec;36(4):213-20. doi: 10.1007/s00795-003-0227-y. Med Electron Microsc. 2003. PMID: 16228654 Review.
Primary deficiency of merosin causes a severe congenital muscular dystrophy (CMD) and a mouse dystrophy (dy/dy mouse). ...Thus, further studies including the functional role of OAs would be required to understand the pathomechanism of merosin-deficient CMD....
Primary deficiency of merosin causes a severe congenital muscular dystrophy (CMD) and a mouse dystrophy (dy/dy mouse). ...Thus, furth …
Prenatal Diagnosis of Merosin-Deficient Muscular Dystrophy.
Fadiloglu E, Ozten G, Unal C, Talim B, Topaloglu H, Beksac MS. Fadiloglu E, et al. Fetal Pediatr Pathol. 2018 Dec;37(6):418-423. doi: 10.1080/15513815.2018.1520944. Epub 2018 Oct 25. Fetal Pediatr Pathol. 2018. PMID: 30358464
GOAL: We evaluated the potential for prenatal diagnosis of merosin-negative muscular dystrophies by immunohistochemistry. MATERIALS AND METHODS: This is a retrospective study of 12 pregnancies with merosin-negative muscular dystrophy in a prior child. ...Eight of th …
GOAL: We evaluated the potential for prenatal diagnosis of merosin-negative muscular dystrophies by immunohistochemistry. MATERIALS A …
Peripheral nerve involvement in merosin-deficient congenital muscular dystrophy and dy mouse.
Matsumura K, Yamada H, Saito F, Sunada Y, Shimizu T. Matsumura K, et al. Neuromuscul Disord. 1997 Jan;7(1):7-12. doi: 10.1016/s0960-8966(96)00402-6. Neuromuscul Disord. 1997. PMID: 9132144 Review.
Merosin, also called laminin-2, is an isoform of laminin comprised of the alpha 2, beta 1 and gamma 1 chains. ...Together with the well known fact that the deposition of laminin in the basement membrane is essential for Schwann cell myelination, these …
Merosin, also called laminin-2, is an isoform of laminin comprised of the alpha 2, beta 1 and gamma 1 chains. ...Togeth …
Myelin abnormalities in merosin-deficient congenital muscular dystrophy.
Saito Y, Ishiyama A, Saito Y, Komaki H, Sasaki M. Saito Y, et al. Muscle Nerve. 2024 Jan;69(1):55-63. doi: 10.1002/mus.28002. Epub 2023 Nov 7. Muscle Nerve. 2024. PMID: 37933889
INTRODUCTION/AIMS: Merosin is a protein complex located in the basement membrane of skeletal muscles and laminin alpha2-containing regions of the central and peripheral nervous systems. ...DISCUSSION: We postulate that the thin myelin associated with MDC1A reflects …
INTRODUCTION/AIMS: Merosin is a protein complex located in the basement membrane of skeletal muscles and laminin alpha2-contai …
Laminin: loss-of-function studies.
Yao Y. Yao Y. Cell Mol Life Sci. 2017 Mar;74(6):1095-1115. doi: 10.1007/s00018-016-2381-0. Epub 2016 Oct 1. Cell Mol Life Sci. 2017. PMID: 27696112 Review.
Not only do these studies suggest novel functions of laminin, but also they provide invaluable animal models that allow investigation of laminin's functions at late stages. Here, I first briefly introduce the nomenclature, structure, and biochemistry of laminin …
Not only do these studies suggest novel functions of laminin, but also they provide invaluable animal models that allow investigation …
[Primary merosin deficiency].
Hayashi YK. Hayashi YK. Ryoikibetsu Shokogun Shirizu. 2001;(35):103-6. Ryoikibetsu Shokogun Shirizu. 2001. PMID: 11555881 Review. Japanese. No abstract available.
Laminin-11.
Miner JH, Patton BL. Miner JH, et al. Int J Biochem Cell Biol. 1999 Aug;31(8):811-6. doi: 10.1016/s1357-2725(99)00030-8. Int J Biochem Cell Biol. 1999. PMID: 10481268 Review.
Consistent with these observations, both motoneurons and Schwann cells distinguish laminin-11 from other isoforms in vitro. These results suggest that laminin-11 is a structural component of the basement membrane which influences cell behavior in physiologically rel …
Consistent with these observations, both motoneurons and Schwann cells distinguish laminin-11 from other isoforms in vitro. These res …
The expanding phenotype of laminin alpha2 chain (merosin) abnormalities: case series and review.
Jones KJ, Morgan G, Johnston H, Tobias V, Ouvrier RA, Wilkinson I, North KN. Jones KJ, et al. J Med Genet. 2001 Oct;38(10):649-57. doi: 10.1136/jmg.38.10.649. J Med Genet. 2001. PMID: 11584042 Free PMC article. Review.
Initial reports of patients with laminin alpha2 chain (merosin) deficiency had a relatively homogeneous phenotype, with classical congenital muscular dystrophy (CMD) characterised by severe muscle weakness, inability to achieve independent ambulation, markedly raise …
Initial reports of patients with laminin alpha2 chain (merosin) deficiency had a relatively homogeneous phenotype, with classi …
27,906 results
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