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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 1
1992 1
1993 1
1998 1
1999 1
2002 2
2009 1
2012 1
2013 1
2014 2
2015 1
2018 1
2020 2
2021 1
2023 1
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16 results

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Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Metadoxine in acute alcohol intoxication: a double-blind, randomized, placebo-controlled study.
Shpilenya LS, Muzychenko AP, Gasbarrini G, Addolorato G. Shpilenya LS, et al. Alcohol Clin Exp Res. 2002 Mar;26(3):340-6. Alcohol Clin Exp Res. 2002. PMID: 11923586 Clinical Trial.
The present study was planned with the aim of investigating the effectiveness of metadoxine in the management of patients affected by acute ethanol intoxication. ...Metadoxine could be helpful in the management of acute ethanol intoxication....
The present study was planned with the aim of investigating the effectiveness of metadoxine in the management of patients affected by …
Metadoxine accelerates fatty liver recovery in alcoholic patients: results of a randomized double-blind, placebo-control trial. Spanish Group for the Study of Alcoholic Fatty Liver.
Caballería J, Parés A, Brú C, Mercader J, García Plaza A, Caballería L, Clemente G, Rodrigo L, Rodés J. Caballería J, et al. J Hepatol. 1998 Jan;28(1):54-60. doi: 10.1016/s0168-8278(98)80202-x. J Hepatol. 1998. PMID: 9537864 Clinical Trial.
In the metadoxine group, the biochemical changes were similar in both the abstinent and the nonabstinent patients. ...Thus, metadoxine could be useful in the treatment of the early stages of alcoholic liver disease....
In the metadoxine group, the biochemical changes were similar in both the abstinent and the nonabstinent patients. ...Thus, metado …
[Capsule metadoxine in the treatment of alcoholic liver disease: a randomized, double-blind, placebo-controlled, multicenter study].
Mao YM, Zeng MD, Li YM, Wang BY, Shang J, Shi RH, Liu JY, Lu LG, Cao AP. Mao YM, et al. Zhonghua Gan Zang Bing Za Zhi. 2009 Mar;17(3):213-6. Zhonghua Gan Zang Bing Za Zhi. 2009. PMID: 19335986 Clinical Trial. Chinese.
OBJECTIVE: To evaluate the efficacy and safety of Capsule metadoxine in the treatment of alcoholic liver disease. METHODS: A randomized double blind multicenter placebo-controlled clinical study was performed to evaluate the therapeutic effectiveness and safety of capsule …
OBJECTIVE: To evaluate the efficacy and safety of Capsule metadoxine in the treatment of alcoholic liver disease. METHODS: A randomiz …
Efficacy of metadoxine extended release in patients with predominantly inattentive subtype attention-deficit/hyperactivity disorder.
Manor I, Newcorn JH, Faraone SV, Adler LA. Manor I, et al. Postgrad Med. 2013 Jul;125(4):181-90. doi: 10.3810/pgm.2013.07.2689. Postgrad Med. 2013. PMID: 23933905 Clinical Trial.
Test of Variables of Attention ADHD scores were significantly decreased in the metadoxine ER group compared with the placebo group for patients with ADHD-PI, but not those with ADHD-CT. CONCLUSION: These data suggest that metadoxine ER is selectively efficacious for …
Test of Variables of Attention ADHD scores were significantly decreased in the metadoxine ER group compared with the placebo group fo …
Metadoxine improves the three- and six-month survival rates in patients with severe alcoholic hepatitis.
Higuera-de la Tijera F, Servín-Caamaño AI, Serralde-Zúñiga AE, Cruz-Herrera J, Pérez-Torres E, Abdo-Francis JM, Salas-Gordillo F, Pérez-Hernández JL. Higuera-de la Tijera F, et al. World J Gastroenterol. 2015 Apr 28;21(16):4975-85. doi: 10.3748/wjg.v21.i16.4975. World J Gastroenterol. 2015. PMID: 25945012 Free PMC article. Clinical Trial.
AIM: To evaluate the impact of metadoxine (MTD) on the 3- and 6-mo survival of patients with severe alcoholic hepatitis (AH). ...
AIM: To evaluate the impact of metadoxine (MTD) on the 3- and 6-mo survival of patients with severe alcoholic hepatitis (AH). ...
Treatment with metadoxine and its impact on early mortality in patients with severe alcoholic hepatitis.
Higuera-de la Tijera F, Servín-Caamaño AI, Cruz-Herrera J, Serralde-Zúñiga AE, Abdo-Francis JM, Gutiérrez-Reyes G, Pérez-Hernández JL. Higuera-de la Tijera F, et al. Ann Hepatol. 2014 May-Jun;13(3):343-52. Ann Hepatol. 2014. PMID: 24756009 Free article. Clinical Trial.
The aim of this study was to evaluate the impact of the addition of metadoxine, a drug which possesses a multifactorial mechanism of action, including antioxidant properties, to standard treatment with glucocorticoids in patients with severe alcoholic hepatitis. ...The fir …
The aim of this study was to evaluate the impact of the addition of metadoxine, a drug which possesses a multifactorial mechanism of …
Efficacy of metadoxine in the management of acute alcohol intoxication.
Díaz Martínez MC, Díaz Martínez A, Villamil Salcedo V, Cruz Fuentes C. Díaz Martínez MC, et al. J Int Med Res. 2002 Jan-Feb;30(1):44-51. doi: 10.1177/147323000203000107. J Int Med Res. 2002. PMID: 11921498 Free article. Clinical Trial.
Metadoxine improved the clinical signs of acute alcohol intoxication and accelerated alcohol clearance from the blood, thus supporting existing data. In contrast to previous data, these effects were concurrent but independent. No adverse effects were observed with metad …
Metadoxine improved the clinical signs of acute alcohol intoxication and accelerated alcohol clearance from the blood, thus supportin …
A randomized, double-blind, placebo-controlled, multicenter study evaluating the efficacy, safety, and tolerability of extended-release metadoxine in adults with attention-deficit/hyperactivity disorder.
Manor I, Ben-Hayun R, Aharon-Peretz J, Salomy D, Weizman A, Daniely Y, Megiddo D, Newcorn JH, Biederman J, Adler LA. Manor I, et al. J Clin Psychiatry. 2012 Dec;73(12):1517-23. doi: 10.4088/JCP.12m07767. J Clin Psychiatry. 2012. PMID: 23290324 Free article. Clinical Trial.
Metadoxine ER was generally well tolerated, with nausea (17% [10/58] vs 0% [0/59]), fatigue (31% [18/58] vs 27% [16/59]), and headaches (29% [17/58] vs 39% [23/59]) being the most frequently reported adverse effects for the metadoxine ER and placebo groups, respecti …
Metadoxine ER was generally well tolerated, with nausea (17% [10/58] vs 0% [0/59]), fatigue (31% [18/58] vs 27% [16/59]), and headach …
[Effects of metadoxine on main biohumoral changes induced by chronic alcoholism].
Corsini G, Gelso E, Giuliano G. Corsini G, et al. Clin Ter. 1992 Mar;140(3):251-7. Clin Ter. 1992. PMID: 1568369 Clinical Trial. Italian.
The paper aims to evaluate the effects of metadoxine on liver function tests in chronic alcohol abusers without a clear alcohol dependence, by means of an open trial carried out in 7 hospitals in Tuscany. ...No unfavorable side effects were observed that could be attribute …
The paper aims to evaluate the effects of metadoxine on liver function tests in chronic alcohol abusers without a clear alcohol depen …
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