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88 results

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Page 1
Screening of flavor compounds using Ucp1-luciferase reporter beige adipocytes identified 5-methylquinoxaline as a novel UCP1-inducing compound.
Kawarasaki S, Matsuo K, Kuwata H, Zhou L, Kwon J, Ni Z, Takahashi H, Nomura W, Kenmotsu H, Inoue K, Kawada T, Goto T. Kawarasaki S, et al. Biosci Biotechnol Biochem. 2022 Feb 24;86(3):380-389. doi: 10.1093/bbb/zbab216. Biosci Biotechnol Biochem. 2022. PMID: 34935880
Using this reporter preadipocyte line, 654 flavor compounds were screened, and a novel Ucp1 expression-inducing compound, 5-methylquinoxaline, was identified. Adipocytes treated with 5-methylquinoxaline showed increased Ucp1 mRNA expression levels and enhanced oxyge …
Using this reporter preadipocyte line, 654 flavor compounds were screened, and a novel Ucp1 expression-inducing compound, 5-methylquinoxa …
Synthesis of deuterium-labeled 2-quinoxalinecarboxylic acid and 3-methylquinoxaline-2-carboxylic acid from deuterium aniline.
Chen W, Zhao C, Deng X. Chen W, et al. J Labelled Comp Radiopharm. 2018 Dec;61(14):1043-1047. doi: 10.1002/jlcr.3679. Epub 2018 Sep 2. J Labelled Comp Radiopharm. 2018. PMID: 30132955
An efficient and simple synthetic route of deuterium-labeled 2-quinoxalinecarboxylic acid-d(4) (QCA-d(4) ) and 3-methylquinoxaline-2-carboxylic acid-d(4) (MQCA-d(4) ) is presented with 99.9% and 99.6% isotopic enrichment using aniline-d(5) as labeled starting material. ...
An efficient and simple synthetic route of deuterium-labeled 2-quinoxalinecarboxylic acid-d(4) (QCA-d(4) ) and 3-methylquinoxaline-2- …
RIFM fragrance ingredient safety assessment, 5-methylquinoxaline, CAS Registry Number 13708-12-8.
Api AM, Belsito D, Botelho D, Bruze M, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Fryer AD, Jones L, Joshi K, Kumar M, Lapczynski A, Lavelle M, Lee I, Liebler DC, Moustakas H, Muldoon J, Penning TM, Ritacco G, Romine J, Sadekar N, Schultz TW, Selechnik D, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, Tokura Y. Api AM, et al. Food Chem Toxicol. 2024 Mar;183 Suppl 1:114364. doi: 10.1016/j.fct.2023.114364. Epub 2023 Dec 13. Food Chem Toxicol. 2024. PMID: 38101605 No abstract available.
2-(3-Aryl-2-propenoyl)-3-methylquinoxaline-1,4-dioxides: a novel cluster of tumor-specific cytotoxins which reverse multidrug resistance.
Das U, Pati HN, Panda AK, De Clercq E, Balzarini J, Molnár J, Baráth Z, Ocsovszki I, Kawase M, Zhou L, Sakagami H, Dimmock JR. Das U, et al. Bioorg Med Chem. 2009 Jun 1;17(11):3909-15. doi: 10.1016/j.bmc.2009.04.021. Epub 2009 Apr 17. Bioorg Med Chem. 2009. PMID: 19427790 Free PMC article.
A series of 2-(3-aryl-2-propenoyl)-3-methylquinoxaline-1,4-dioxides 3a-l were prepared by condensation of various aryl aldehydes with 2-acetyl-3-methylquinoxaline-1,4-dioxide 2. ...
A series of 2-(3-aryl-2-propenoyl)-3-methylquinoxaline-1,4-dioxides 3a-l were prepared by condensation of various aryl aldehydes with …
Design, synthesis, docking, ADMET studies, and anticancer evaluation of new 3-methylquinoxaline derivatives as VEGFR-2 inhibitors and apoptosis inducers.
Alanazi MM, Eissa IH, Alsaif NA, Obaidullah AJ, Alanazi WA, Alasmari AF, Albassam H, Elkady H, Elwan A. Alanazi MM, et al. J Enzyme Inhib Med Chem. 2021 Dec;36(1):1760-1782. doi: 10.1080/14756366.2021.1956488. J Enzyme Inhib Med Chem. 2021. PMID: 34340610 Free PMC article.
Inhibition of VEGFR-2 activity proved effective suppression of tumour propagation. Accordingly, two series of new 3-methylquinoxaline derivatives have been designed and synthesised as VEGFR-2 inhibitors. ...
Inhibition of VEGFR-2 activity proved effective suppression of tumour propagation. Accordingly, two series of new 3-methylquinoxaline …
[Determination of 3-methylquinoxaline-2-carboxylic acid of olaquindox marker residue in chicken muscles by liquid chromatography-tandem mass spectrometry].
Li E, Zhang M, Ma H, Zhang J, Liu R, Zeng Z, He L. Li E, et al. Se Pu. 2018 May 8;36(5):446-451. doi: 10.3724/SP.J.1123.2017.12023. Se Pu. 2018. PMID: 30136485 Chinese.
A simple, sensitive, scientific and reproducible liquid chromatography-tandem mass spectrometric method was developed to determine 3-methylquinoxaline-2-carboxylic acid (MQCA) of olaquindox marker residue in chicken muscle tissues. ...
A simple, sensitive, scientific and reproducible liquid chromatography-tandem mass spectrometric method was developed to determine 3-meth …
88 results