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Page 1
Microglia-mediated demyelination protects against CD8+ T cell-driven axon degeneration in mice carrying PLP defects.
Nat Commun. 2023 Oct 30;14(1):6911. doi: 10.1038/s41467-023-42570-2.
Nat Commun. 2023.
PMID: 37903797
Free PMC article.
CNS-associated T-lymphocytes in a mouse model of Hereditary Spastic Paraplegia type 11 (SPG11) are therapeutic targets for established immunomodulators.
Hörner M, Groh J, Klein D, Ilg W, Schöls L, Dos Santos S, Bergmann A, Klebe S, Cauhape M, Branchu J, El Hachimi KH, Stevanin G, Darios F, Martini R.
Hörner M, et al.
Exp Neurol. 2022 Sep;355:114119. doi: 10.1016/j.expneurol.2022.114119. Epub 2022 May 20.
Exp Neurol. 2022.
PMID: 35605667
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Pathogenic inflammation in the CNS of mice carrying human PLP1 mutations.
Groh J, Friedman HC, Orel N, Ip CW, Fischer S, Spahn I, Schäffner E, Hörner M, Stadler D, Buttmann M, Varallyay C, Solymosi L, Sendtner M, Peterson AC, Martini R.
Groh J, et al. Among authors: horner m.
Hum Mol Genet. 2016 Nov 1;25(21):4686-4702. doi: 10.1093/hmg/ddw296.
Hum Mol Genet. 2016.
PMID: 28173160
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Clinically approved immunomodulators ameliorate behavioral changes in a mouse model of hereditary spastic paraplegia type 11.
Hörner M, Popp S, Branchu J, Stevanin G, Darios F, Klebe S, Groh J, Martini R.
Hörner M, et al.
Front Neurosci. 2024 Feb 16;18:1299554. doi: 10.3389/fnins.2024.1299554. eCollection 2024.
Front Neurosci. 2024.
PMID: 38435059
Free PMC article.
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Unraveling Axonal Transcriptional Landscapes: Insights from iPSC-Derived Cortical Neurons and Implications for Motor Neuron Degeneration.
Xu J, Hörner M, Nagel M, Korneck M, Noß M, Hauser S, Schöls L, Admard J, Casadei N, Schüle R.
Xu J, et al. Among authors: horner m.
bioRxiv [Preprint]. 2024 Mar 29:2024.03.26.586780. doi: 10.1101/2024.03.26.586780.
bioRxiv. 2024.
PMID: 38585749
Free PMC article.
Preprint.
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Teriflunomide attenuates neuroinflammation-related neural damage in mice carrying human PLP1 mutations.
Groh J, Hörner M, Martini R.
Groh J, et al. Among authors: horner m.
J Neuroinflammation. 2018 Jul 3;15(1):194. doi: 10.1186/s12974-018-1228-z.
J Neuroinflammation. 2018.
PMID: 29970109
Free PMC article.
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