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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1983 1
1984 4
1985 11
1986 15
1987 16
1988 23
1989 28
1990 29
1991 28
1992 32
1993 44
1994 39
1995 35
1996 37
1997 24
1998 31
1999 27
2000 32
2001 22
2002 25
2003 36
2004 32
2005 31
2006 35
2007 36
2008 42
2009 42
2010 36
2011 27
2012 34
2013 43
2014 35
2015 32
2016 41
2017 34
2018 32
2019 39
2020 28
2021 35
2022 39
2023 27
2024 10

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1,161 results

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Page 1
Antiprogestins for breast cancer treatment: We are almost ready.
Elia A, Pataccini G, Saldain L, Ambrosio L, Lanari C, Rojas P. Elia A, et al. J Steroid Biochem Mol Biol. 2024 Mar 28;241:106515. doi: 10.1016/j.jsbmb.2024.106515. Online ahead of print. J Steroid Biochem Mol Biol. 2024. PMID: 38554981
The development of antiprogestins was initially a gynecological purpose. However, since mifepristone was developed, its application for breast cancer treatment was immediately proposed. ...We highlight the potential use of antiprogestins in breast cancer prev …
The development of antiprogestins was initially a gynecological purpose. However, since mifepristone was developed, its application f …
Natural Killer Cell Dysfunction in Premenopausal BRCA1 Mutation Carriers: A Potential Mechanism for Ovarian Carcinogenesis.
Haran S, Chindera K, Sabry M, Wilkinson N, Arora R, Zubiak A, Bartlett TE, Evans I, Jones A, Reisel D, Herzog C, Alkasalias T, Newman M, Kim J, Rådestad AF, Gemzell-Danielsson K, Rosenthal AN, Dubeau L, Lowdell MW, Widschwendter M. Haran S, et al. Cancers (Basel). 2024 Mar 18;16(6):1186. doi: 10.3390/cancers16061186. Cancers (Basel). 2024. PMID: 38539519 Free PMC article.
We aimed to assess the cell autonomous and cell-nonautonomous implications of a germline BRCA1 mutation in the context of cancer immunosurveillance of CD3(-) CD56(+) natural killer (NK) cells. ...Hypoxia-inducible factor 1-alpha (HIF-1alpha) immunohistochemistry of canc
We aimed to assess the cell autonomous and cell-nonautonomous implications of a germline BRCA1 mutation in the context of cancer immu …
Selective Modulation of the Human Glucocorticoid Receptor Compromises GR Chromatin Occupancy and Recruitment of p300/CBP and the Mediator Complex.
Van Moortel L, Verhee A, Thommis J, Houtman R, Melchers D, Delhaye L, Van Leene C, Hellemans M, Gevaert K, Eyckerman S, De Bosscher K. Van Moortel L, et al. Mol Cell Proteomics. 2024 Mar;23(3):100741. doi: 10.1016/j.mcpro.2024.100741. Epub 2024 Feb 20. Mol Cell Proteomics. 2024. PMID: 38387774 Free PMC article.
Exogenous glucocorticoids are frequently used to treat inflammatory disorders and as adjuncts for the treatment of solid cancers. However, their use is associated with severe side effects and therapy resistance. ...
Exogenous glucocorticoids are frequently used to treat inflammatory disorders and as adjuncts for the treatment of solid cancers. How …
Significant Palliative Benefits Following Therapy With Mifepristone for Advanced Treatment Resistant Small Cell Lung Cancer.
Check JH, Check DL, DO TP, Srivastava M, Check E. Check JH, et al. Anticancer Res. 2024 Feb;44(2):659-664. doi: 10.21873/anticanres.16855. Anticancer Res. 2024. PMID: 38307551
BACKGROUND/AIM: Progesterone receptor antagonists have been found to provide significant extension of life and considerable palliative benefits in a large variety of very advanced cancers. Most of these treated cancers lack the classical nuclear progesterone recepto …
BACKGROUND/AIM: Progesterone receptor antagonists have been found to provide significant extension of life and considerable palliative benef …
Establishment of tumor microenvironment-preserving organoid model from patients with intracranial meningioma.
Kim D, Park J, Park HC, Zhang S, Park M, Park SA, Lee SH, Lee YS, Park JS, Jeun SS, Chung YJ, Ahn S. Kim D, et al. Cancer Cell Int. 2024 Jan 18;24(1):36. doi: 10.1186/s12935-024-03225-4. Cancer Cell Int. 2024. PMID: 38238738 Free PMC article.
As a representative application, we utilized MNOs in drug screening, and mifepristone, an antagonist of progesterone receptor, showed prominent antitumor efficacy with respect to viability, invasiveness, and protein expression. ...
As a representative application, we utilized MNOs in drug screening, and mifepristone, an antagonist of progesterone receptor, showed …
[Tongxie Yaofang regulates tumor-associated macrophage polarization in colorectal cancer under chronic stress].
Yang Y, Hu YE, Huang YQ, Jiang YF, Fu X, You FM. Yang Y, et al. Zhongguo Zhong Yao Za Zhi. 2023 Nov;48(22):6142-6153. doi: 10.19540/j.cnki.cjcmm.20230811.703. Zhongguo Zhong Yao Za Zhi. 2023. PMID: 38114221 Chinese.
This study aims to investigate the intervention effect and mechanism of Tongxie Yaofang in regulating tumor-associated macrophage polarization on colorectal cancer under chronic stress. BALB/C mice were randomized into blank, control, model, mifepristone, and low-, …
This study aims to investigate the intervention effect and mechanism of Tongxie Yaofang in regulating tumor-associated macrophage polarizati …
Repositioning of mifepristone as an integrated stress response activator to potentiate cisplatin efficacy in non-small cell lung cancer.
Namkaew J, Zhang J, Yamakawa N, Hamada Y, Tsugawa K, Oyadomari M, Miyake M, Katagiri T, Oyadomari S. Namkaew J, et al. Cancer Lett. 2024 Feb 1;582:216509. doi: 10.1016/j.canlet.2023.216509. Epub 2023 Nov 28. Cancer Lett. 2024. PMID: 38036042
Lung cancer, primarily non-small-cell lung cancer (NSCLC), is a significant cause of cancer-related mortality worldwide. ...To expedite and economize the development of chemosensitizers for cisplatin treatment in NSCLC, we employed a strategy to screen an FDA …
Lung cancer, primarily non-small-cell lung cancer (NSCLC), is a significant cause of cancer-related mortality worldwide …
The inhibitory effect of trastuzumab on BT474 triple-positive breast cancer cell viability is reversed by the combination of progesterone and estradiol.
López-Méndez JA, Ventura-Gallegos JL, Camacho-Arroyo I, Lizano M, Cabrera-Quintero AJ, Romero-Córdoba SL, Martínez-Vázquez M, Jacobo-Herrera NJ, León-Del-Río A, Paredes-Villa AA, Zentella-Dehesa A. López-Méndez JA, et al. Oncol Lett. 2023 Nov 15;27(1):19. doi: 10.3892/ol.2023.14152. eCollection 2024 Jan. Oncol Lett. 2023. PMID: 38034484 Free PMC article.
Breast cancer expressing the estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor-2 (HER2) is known as triple-positive (TPBC). TPBC represents 9-11% of breast cancer cases worldwide and is a heterogeneous subtype. Notably, TP …
Breast cancer expressing the estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor-2 (HER2) i …
1,161 results