Ex vivo characterization of particle transport in mucus secretions coating freshly excised mucosal tissues.
Ensign LM, Henning A, Schneider CS, Maisel K, Wang YY, Porosoff MD, Cone R, Hanes J.
Ensign LM, et al.
Mol Pharm. 2013 Jun 3;10(6):2176-82. doi: 10.1021/mp400087y. Epub 2013 May 23.
Mol Pharm. 2013.
PMID: 23617606
Free PMC article.
Thus, it is important to evaluate the mucus-penetrating ability of nanosized delivery systems in preclinical animal studies, and for administration to humans. We describe a simple ex vivo method to visualize and quantify nanoparticle transport in mucus on fresh muco …
Thus, it is important to evaluate the mucus-penetrating ability of nanosized delivery systems in preclinical animal studies, and for …