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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 1
1970 3
1971 2
1972 1
1973 3
1974 7
1975 6
1976 9
1977 14
1978 13
1979 20
1980 12
1981 9
1982 13
1983 16
1984 22
1985 21
1986 17
1987 18
1988 19
1989 24
1990 28
1991 30
1992 23
1993 36
1994 24
1995 40
1996 49
1997 32
1998 42
1999 40
2000 44
2001 44
2002 56
2003 46
2004 65
2005 82
2006 76
2007 82
2008 83
2009 82
2010 88
2011 100
2012 94
2013 111
2014 102
2015 96
2016 86
2017 94
2018 89
2019 103
2020 113
2021 105
2022 45
2023 58
2024 28

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2,380 results

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Page 1
Cell-type-specific metabolic labeling of nascent proteomes in vivo.
Alvarez-Castelao B, Schanzenbächer CT, Hanus C, Glock C, Tom Dieck S, Dörrbaum AR, Bartnik I, Nassim-Assir B, Ciirdaeva E, Mueller A, Dieterich DC, Tirrell DA, Langer JD, Schuman EM. Alvarez-Castelao B, et al. Nat Biotechnol. 2017 Dec;35(12):1196-1201. doi: 10.1038/nbt.4016. Epub 2017 Nov 6. Nat Biotechnol. 2017. PMID: 29106408 Free article.
This is because the existing methods for metabolic protein labeling in vivo access all cell types. We report the development of a transgenic mouse line where Cre-recombinase-induced expression of a mutant methionyl-tRNA synthetase (L274G) enables the cell-type-specific lab …
This is because the existing methods for metabolic protein labeling in vivo access all cell types. We report the development of a transgenic …
Phase-separated ribosome-nascent chain complexes in genotoxic stress response.
Németh-Szatmári O, Nagy-Mikó B, Györkei Á, Varga D, Kovács BBH, Igaz N, Bognár B, Rázga Z, Nagy G, Zsindely N, Bodai L, Papp B, Erdélyi M, Kiricsi M, Blastyák A, Collart MA, Boros IM, Villányi Z. Németh-Szatmári O, et al. RNA. 2023 Oct;29(10):1557-1574. doi: 10.1261/rna.079755.123. Epub 2023 Jul 17. RNA. 2023. PMID: 37460154 Free article.
Assemblysomes are EDTA- and RNase-resistant ribonucleoprotein (RNP) complexes of paused ribosomes with protruding nascent polypeptide chains. They have been described in yeast and human cells for the proteasome subunit Rpt1, and the disordered amino-terminal part of the …
Assemblysomes are EDTA- and RNase-resistant ribonucleoprotein (RNP) complexes of paused ribosomes with protruding nascent polypeptide …
Eyes on Translation.
Chekulaeva M, Landthaler M. Chekulaeva M, et al. Mol Cell. 2016 Sep 15;63(6):918-25. doi: 10.1016/j.molcel.2016.08.031. Mol Cell. 2016. PMID: 27635758 Free article. Review.
., 2016) describing novel approaches to imaging in real time the synthesis of nascent peptides from individual mRNAs in living cells....
., 2016) describing novel approaches to imaging in real time the synthesis of nascent peptides from individual mRNAs in living cells. …
Mindfulness in PTSD treatment.
Lang AJ. Lang AJ. Curr Opin Psychol. 2017 Apr;14:40-43. doi: 10.1016/j.copsyc.2016.10.005. Epub 2016 Nov 2. Curr Opin Psychol. 2017. PMID: 28813317 Review.
Several types of interventions that incorporate principles of mindfulness have been examined for treatment of posttraumatic stress disorder (PTSD). This nascent literature is inconsistent and methodologically limited but does suggest that mindfulness is a potentially impor …
Several types of interventions that incorporate principles of mindfulness have been examined for treatment of posttraumatic stress disorder …
miRNA-mediated loss of m6A increases nascent translation in glioblastoma.
Zepecki JP, Karambizi D, Fajardo JE, Snyder KM, Guetta-Terrier C, Tang OY, Chen JS, Sarkar A, Fiser A, Toms SA, Tapinos N. Zepecki JP, et al. PLoS Genet. 2021 Mar 8;17(3):e1009086. doi: 10.1371/journal.pgen.1009086. eCollection 2021 Mar. PLoS Genet. 2021. PMID: 33684100 Free PMC article.
Ectopic expression of the RRACH-binding miR-145 induces loss of m6A, formation of FTO/AGO1/ILF3/miR-145 complexes on a clinically relevant tumor suppressor gene (CLIP3) and significant increase in its nascent translation. Inhibition of miR-145 maintains RRACH m6A levels of …
Ectopic expression of the RRACH-binding miR-145 induces loss of m6A, formation of FTO/AGO1/ILF3/miR-145 complexes on a clinically relevant t …
Culture and early social-cognitive development.
Kärtner J, Schuhmacher N, Giner Torréns M. Kärtner J, et al. Prog Brain Res. 2020;254:225-246. doi: 10.1016/bs.pbr.2020.06.011. Epub 2020 Jul 16. Prog Brain Res. 2020. PMID: 32859289 Review.
Overall, the current cross-cultural research suggests universality without uniformity: the common suite of social-cognitive skills emerges reliably and, at the same time, there are culture-specific accentuations of social-cognitive development across domains that mostly are in …
Overall, the current cross-cultural research suggests universality without uniformity: the common suite of social-cognitive skills emerges r …
The Biogenesis of Nascent Circular RNAs.
Zhang Y, Xue W, Li X, Zhang J, Chen S, Zhang JL, Yang L, Chen LL. Zhang Y, et al. Cell Rep. 2016 Apr 19;15(3):611-624. doi: 10.1016/j.celrep.2016.03.058. Epub 2016 Apr 7. Cell Rep. 2016. PMID: 27068474 Free article.
Steady-state circular RNAs (circRNAs) have been mapped to thousands of genomic loci in mammals. We studied circRNA processing using metabolic tagging of nascent RNAs with 4-thiouridine (4sU). Strikingly, the efficiency of circRNA processing from pre-mRNA is extremely low e …
Steady-state circular RNAs (circRNAs) have been mapped to thousands of genomic loci in mammals. We studied circRNA processing using metaboli …
Preparation of Mammalian Nascent RNA for Long Read Sequencing.
Reimer KA, Neugebauer KM. Reimer KA, et al. Curr Protoc Mol Biol. 2020 Dec;133(1):e128. doi: 10.1002/cpmb.128. Curr Protoc Mol Biol. 2020. PMID: 33085989 Free PMC article.
Here, we describe how to isolate nascent RNA from mammalian cells through subcellular fractionation of chromatin-associated RNA, as well as how to deplete poly(A)(+) RNA and rRNA, and, finally, how to generate a full-length cDNA library for use on long read sequencing plat …
Here, we describe how to isolate nascent RNA from mammalian cells through subcellular fractionation of chromatin-associated RNA, as w …
Nascent RNA scaffolds contribute to chromosome territory architecture and counter chromatin compaction.
Creamer KM, Kolpa HJ, Lawrence JB. Creamer KM, et al. Mol Cell. 2021 Sep 2;81(17):3509-3525.e5. doi: 10.1016/j.molcel.2021.07.004. Epub 2021 Jul 27. Mol Cell. 2021. PMID: 34320406 Free PMC article.
RNA-seq analysis reveals that most RNA in the nuclear scaffold is repeat-rich, non-coding, and derived predominantly from introns of nascent transcripts. Insoluble, repeat-rich (C(0)T-1) RNA co-distributes with known scaffold proteins including scaffold attachment factor A …
RNA-seq analysis reveals that most RNA in the nuclear scaffold is repeat-rich, non-coding, and derived predominantly from introns of nasc …
Reversible Fluorescent Probes for Biological Redox States.
Kaur A, Kolanowski JL, New EJ. Kaur A, et al. Angew Chem Int Ed Engl. 2016 Jan 26;55(5):1602-13. doi: 10.1002/anie.201506353. Epub 2015 Dec 2. Angew Chem Int Ed Engl. 2016. PMID: 26630348 Review.
In this review, we discuss the current progress towards such probes, and identify key directions for future research in this nascent field of vital biological interest....
In this review, we discuss the current progress towards such probes, and identify key directions for future research in this nascent …
2,380 results