Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1915 1
1976 2
1979 1
1983 1
1989 4
1990 8
1991 18
1992 16
1993 17
1994 15
1995 16
1996 19
1997 15
1998 24
1999 7
2000 17
2001 20
2002 9
2003 15
2004 10
2005 17
2006 15
2007 16
2008 14
2009 15
2010 17
2011 17
2012 11
2013 15
2014 12
2015 15
2016 10
2017 16
2018 8
2019 13
2020 9
2021 8
2022 3
2023 5
2024 6

Text availability

Article attribute

Article type

Publication date

Search Results

459 results

Results by year

Filters applied: . Clear all
Page 1
Interrupted Nef Reaction of Cyclic Nitronates: Diastereoselective Access to Densely Substituted alpha-Chloronitroso Compounds.
Malykhin RS, Boyko YD, Nelyubina YV, Ioffe SL, Sukhorukov AY. Malykhin RS, et al. J Org Chem. 2022 Dec 16;87(24):16617-16631. doi: 10.1021/acs.joc.2c02281. Epub 2022 Dec 2. J Org Chem. 2022. PMID: 36459679
The reaction is usually diastereoselective, and in some cases stereodivergent formation of isomers at different temperatures is observed. The discovered process represents the first example of an interrupted Nef reaction of nitronic esters. DFT calculations s …
The reaction is usually diastereoselective, and in some cases stereodivergent formation of isomers at different temperatures is obser …
Nef reaction with molecular oxygen in the absence of metal additives, and mechanistic insights.
Umemiya S, Nishino K, Sato I, Hayashi Y. Umemiya S, et al. Chemistry. 2014 Nov 24;20(48):15753-9. doi: 10.1002/chem.201403475. Epub 2014 Sep 22. Chemistry. 2014. PMID: 25251247
A Nef reaction has been developed that is conducted under mildly basic conditions with molecular oxygen as an oxidant, without the need for metal additives. Whereas nitroalkanes are converted into ketones in good yield, nitroalkenes are transformed into alpha,beta-u …
A Nef reaction has been developed that is conducted under mildly basic conditions with molecular oxygen as an oxidant, without …
Interrupted Nef and Meyer Reactions: A Growing Point for Diversity-Oriented Synthesis Based on Nitro Compounds.
Sukhorukov AY. Sukhorukov AY. Molecules. 2023 Jan 10;28(2):686. doi: 10.3390/molecules28020686. Molecules. 2023. PMID: 36677743 Free PMC article. Review.
The Nef reaction (nitro to carbonyl group conversion) and related Meyer reaction are among the key transformations of aliphatic nitro compounds. ...In this review, examples of interrupted Nef and Meyer reactions are summarized, and the prospects …
The Nef reaction (nitro to carbonyl group conversion) and related Meyer reaction are among the key transformations of a …
Upregulated lncRNA-NEF predicts recurrence and poor treatment outcomes of ankylosing spondylitis.
Han D, Ouyang G, Pan P, Yuan Y. Han D, et al. Immun Inflamm Dis. 2022 Aug;10(8):e627. doi: 10.1002/iid3.627. Immun Inflamm Dis. 2022. PMID: 35894706 Free PMC article.
INTRODUCTION: Osteoporosis is related to lncRNA-neighboring enhancer of FOXA2 (NEF) and inversely correlated to ankylosing spondylitis (AS), implying that lncRNA-NEF might also relate to AS. ...LncRNA-NEF expression in synovial fluid samples was analyzed by r …
INTRODUCTION: Osteoporosis is related to lncRNA-neighboring enhancer of FOXA2 (NEF) and inversely correlated to ankylosing spondyliti …
Extension of the Nef reaction to C-glycosylnitromethanes.
Petrusová M, Vojtech M, Pribulová B, Lattová E, Matulová M, Poláková M, BeMiller JN, Kren V, Petrus L. Petrusová M, et al. Carbohydr Res. 2006 Sep 4;341(12):2019-25. doi: 10.1016/j.carres.2006.04.050. Epub 2006 Jun 22. Carbohydr Res. 2006. PMID: 16797501
Structures of the final products of the overall process provide unique evidence that a kinetically controlled, five-membered-ring closure precedes a six-membered-ring closure in reversible systems capable of giving both five-membered and six-membered all-sp3-atom rings. Determina …
Structures of the final products of the overall process provide unique evidence that a kinetically controlled, five-membered-ring closure pr …
Synthesis of 3,5-disubstituted isoxazoles by domino reductive Nef reaction/cyclization of beta-nitroenones.
Khan MEI, Cassini TL, Petrini M, Palmieri A. Khan MEI, et al. Org Biomol Chem. 2024 Apr 24;22(16):3299-3303. doi: 10.1039/d4ob00232f. Org Biomol Chem. 2024. PMID: 38577730
Products are obtained in good yields and several functional groups are tolerated thanks to the mild reaction conditions....
Products are obtained in good yields and several functional groups are tolerated thanks to the mild reaction conditions....
Sequential Reduction of Nitroalkanes Mediated by CS(2) and Amidine/Guanidine Bases: A Controllable Nef Reaction.
Ju M, Guan W, Schomaker JM, Harper KC. Ju M, et al. Org Lett. 2019 Nov 15;21(22):8893-8898. doi: 10.1021/acs.orglett.9b02987. Epub 2019 Oct 28. Org Lett. 2019. PMID: 31657582
In this letter, we describe a mild, functional group-tolerant reductive Nef reaction that utilizes CS(2) and an amidine or guanidine base to sequentially cleave N-O bonds. ...
In this letter, we describe a mild, functional group-tolerant reductive Nef reaction that utilizes CS(2) and an amidine or gua …
LncRNA-NEF inhibits proliferation, migration and invasion of esophageal squamous-cell carcinoma cells by inactivating wnt/beta-catenin pathway.
Zhang J, Hu SL, Qiao CH, Ye JF, Li M, Ma HM, Wang JH, Xin SY, Yuan ZL. Zhang J, et al. Eur Rev Med Pharmacol Sci. 2018 Oct;22(20):6824-6831. doi: 10.26355/eurrev_201810_16150. Eur Rev Med Pharmacol Sci. 2018. PMID: 30402846 Free article.
The expression of NEF was detected by quantitative Real-Time Polymerase Chain Reaction (qRT-PCR). ...NEF overexpression decreased the expression levels of wnt/beta-catenin pathway-related proteins, while Wnt activator showed no significant effects on NEF …
The expression of NEF was detected by quantitative Real-Time Polymerase Chain Reaction (qRT-PCR). ...NEF overexpression …
HIV-1 Nef impairs multiple T-cell functions in antigen-specific immune response in mice.
Fujii H, Ato M, Takahashi Y, Otake K, Hashimoto S, Kaji T, Tsunetsugu-Yokota Y, Fujita M, Adachi A, Nakayama T, Taniguchi M, Koyasu S, Takemori T. Fujii H, et al. Int Immunol. 2011 Jul;23(7):433-41. doi: 10.1093/intimm/dxr031. Epub 2011 Jun 3. Int Immunol. 2011. PMID: 21642447
Likewise, the in vivo effects of Nef transgenic mouse models supported T-cell hyperresponse by Nef. ...These results support a model, in which Nef expression does not cause T-cell hyperresponse in immune reaction, but instead reduces the T-cell activit …
Likewise, the in vivo effects of Nef transgenic mouse models supported T-cell hyperresponse by Nef. ...These results support a …
One Reacts as Two: Applications of N-Isocyaniminotriphenylphosphorane in Diversity-Oriented Synthesis.
Ojeda-Carralero GM, Ceballos LG, Coro J, Rivera DG. Ojeda-Carralero GM, et al. ACS Comb Sci. 2020 Oct 12;22(10):475-494. doi: 10.1021/acscombsci.0c00111. Epub 2020 Sep 8. ACS Comb Sci. 2020. PMID: 32631055 Review.
NIITP combines the reactivity of isonitriles with that of phosphoranes to enable chemical transformations employed in the construction of compound libraries. Here, we cover from the initial applications of NIITP in the Nef isocyanide reaction to further derivations …
NIITP combines the reactivity of isonitriles with that of phosphoranes to enable chemical transformations employed in the construction of co …
459 results