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Nizatidine.
[No authors listed] [No authors listed] 2021 Feb 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2021 Feb 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000299 Free Books & Documents. Review.
Because of the low levels of nizatidine in breastmilk, amounts ingested by the infant are small and would not be expected to cause any adverse effects in breastfed infants. ...
Because of the low levels of nizatidine in breastmilk, amounts ingested by the infant are small and would not be expected to cause an …
Nizatidine.
[No authors listed] [No authors listed] 2018 Jan 25. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2018 Jan 25. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 31643707 Free Books & Documents. Review.
Nizatidine is a histamine type 2 receptor antagonist (H2 blocker) which is widely used for treatment of acid-peptic disease and heartburn. Nizatidine has been linked to rare instances of clinically apparent acute liver injury....
Nizatidine is a histamine type 2 receptor antagonist (H2 blocker) which is widely used for treatment of acid-peptic disease and heart …
[Nizatidine].
Romero M, Franzosi MG. Romero M, et al. Medicina (Firenze). 1989 Jan-Mar;9(1):93-6. Medicina (Firenze). 1989. PMID: 2567957 Review. Italian.
Nizatidine is a new H2-receptor antagonist, as potent as ranitidine. ...Published clinical trials are limited. Over 3800 patients who have been treated with nizatidine, 300 mg for up to eight weeks or 150 mg at night for a year, did not appear to have significantly …
Nizatidine is a new H2-receptor antagonist, as potent as ranitidine. ...Published clinical trials are limited. Over 3800 patients who …
Nizatidine. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic use in peptic ulcer disease.
Price AH, Brogden RN. Price AH, et al. Drugs. 1988 Nov;36(5):521-39. doi: 10.2165/00003495-198836050-00002. Drugs. 1988. PMID: 2905640 Review.
Similarly, studies in humans have confirmed that nizatidine is a potent inhibitor of basal, nocturnal and stimulated gastric acid secretion. ...Nizatidine is well tolerated. Unlike cimetidine it does not have any antiandrogenic effects or alter the hepatic metabolis …
Similarly, studies in humans have confirmed that nizatidine is a potent inhibitor of basal, nocturnal and stimulated gastric acid sec …
Effects of ranitidine and nizatidine on the risk of gastrointestinal cancer.
Kang H, Nam CM, Choi DW, Park S. Kang H, et al. Front Oncol. 2023 Jul 27;13:1182174. doi: 10.3389/fonc.2023.1182174. eCollection 2023. Front Oncol. 2023. PMID: 37576886 Free PMC article.
However, in 2019, the US Food and Drug Administration announced that the drugs ranitidine and nizatidine, which are used for digestive disorders, contain carcinogens. ...Through this procedure, 22,931 cases and 68,793 controls were identified. The associations of ranitidin …
However, in 2019, the US Food and Drug Administration announced that the drugs ranitidine and nizatidine, which are used for digestiv …
Pharmacology and toxicology of nizatidine.
Morton DM. Morton DM. Scand J Gastroenterol Suppl. 1987;136:1-8. doi: 10.3109/00365528709094479. Scand J Gastroenterol Suppl. 1987. PMID: 2892249 Review.
In well-established animal models, nizatidine is a potent, specific, and competitive orally active H2-receptor antagonist. ...Nizatidine was well-tolerated in animals after both intravenous and oral administration and following single or repeated administration....
In well-established animal models, nizatidine is a potent, specific, and competitive orally active H2-receptor antagonist. ...Niza …
Nizatidine anaphylaxis.
Mira-Perceval JL, Ortiz JL, Sarrió F, Miralles JC, Hernández J, Negro-Alvarez JM, López-Sánchez JD, García-Sellés FJ, Pagán JA. Mira-Perceval JL, et al. J Allergy Clin Immunol. 1996 Mar;97(3):855-6. doi: 10.1016/s0091-6749(96)80165-5. J Allergy Clin Immunol. 1996. PMID: 8613644 No abstract available.
A pharmacokinetic profile of nizatidine in man.
Callaghan JT, Bergstrom RF, Rubin A, Chernish S, Crabtree R, Knadler MP, Obermeyer B, Offen WW, Schneck DW, Aronoff G, et al. Callaghan JT, et al. Scand J Gastroenterol Suppl. 1987;136:9-17. doi: 10.3109/00365528709094480. Scand J Gastroenterol Suppl. 1987. PMID: 2892261 Review.
The absolute oral bioavailability of nizatidine exceeded 90%; the half-life (t1/2), plasma clearance (Clp), and volume of distribution (Vd) of iv nizatidine were 1.3 h, 461/h, and 1.21/kg, respectively. ...Nizatidine was three times more potent than cimetidin …
The absolute oral bioavailability of nizatidine exceeded 90%; the half-life (t1/2), plasma clearance (Clp), and volume of distributio …
Regulatory Updates and Analytical Methodologies for Nitrosamine Impurities Detection in Sartans, Ranitidine, Nizatidine, and Metformin along with Sample Preparation Techniques.
Shaik KM, Sarmah B, Wadekar GS, Kumar P. Shaik KM, et al. Crit Rev Anal Chem. 2022;52(1):53-71. doi: 10.1080/10408347.2020.1788375. Epub 2020 Jul 21. Crit Rev Anal Chem. 2022. PMID: 32691615 Review.
Nitrosamine impurities have been detected in various pharmaceutical products in recent days. Various sartans, ranitidine, nizatidine, and metformin have been recalled from the markets due to the high limit of nitrosamine impurities. ...Various detection methods including L …
Nitrosamine impurities have been detected in various pharmaceutical products in recent days. Various sartans, ranitidine, nizatidine, …
Nizatidine interacts with ct-DNA causing genotoxicity and cytotoxicity: an assessment by in vitro, in vivo, and in silico studies.
Rahman Y, Afrin S, Perwez A, Ansari MO, Sarwar T, Ahmed S, Rizvi MA, Shadab GGHA, Tabish M. Rahman Y, et al. J Biomol Struct Dyn. 2023 Feb;41(2):538-549. doi: 10.1080/07391102.2021.2008496. Epub 2021 Dec 3. J Biomol Struct Dyn. 2023. PMID: 34856883
DNA damage occurred at high concentrations of nizatidine. Genotoxicity of nizatidine was also evaluated in vivo by assessing cytogenetic biomarkers viz. micronuclei formation and chromosomal aberration test. Nizatidine was able to induce micronuclei formation …
DNA damage occurred at high concentrations of nizatidine. Genotoxicity of nizatidine was also evaluated in vivo by assessing c …
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