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Did you mean nm and health (50,823 results)?
Nicotinamide mononucleotide (NMN) as an anti-aging health product - Promises and safety concerns.
Nadeeshani H, Li J, Ying T, Zhang B, Lu J. Nadeeshani H, et al. J Adv Res. 2021 Aug 11;37:267-278. doi: 10.1016/j.jare.2021.08.003. eCollection 2022 Mar. J Adv Res. 2021. PMID: 35499054 Free PMC article. Review.
BACKGROUND: Elderly population has been progressively rising in the world, thus the demand for anti-aging heath products to assure longevity as well as to ameliorate age-related complications is also on the rise. Among various anti-aging health products, nicotinamide monon …
BACKGROUND: Elderly population has been progressively rising in the world, thus the demand for anti-aging heath products to assure longevity …
NAD(+) Intermediates: The Biology and Therapeutic Potential of NMN and NR.
Yoshino J, Baur JA, Imai SI. Yoshino J, et al. Cell Metab. 2018 Mar 6;27(3):513-528. doi: 10.1016/j.cmet.2017.11.002. Epub 2017 Dec 14. Cell Metab. 2018. PMID: 29249689 Free PMC article. Review.
In particular, two key NAD(+) intermediates, nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN), have been extensively studied over the past several years. ...A comprehensive concept that connects NAD(+) metabolism to the control of aging and longevity in mam …
In particular, two key NAD(+) intermediates, nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN), have been extensively …
The efficacy and safety of beta-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial.
Yi L, Maier AB, Tao R, Lin Z, Vaidya A, Pendse S, Thasma S, Andhalkar N, Avhad G, Kumbhar V. Yi L, et al. Geroscience. 2023 Feb;45(1):29-43. doi: 10.1007/s11357-022-00705-1. Epub 2022 Dec 8. Geroscience. 2023. PMID: 36482258 Free PMC article. Clinical Trial.
Blood NAD concentrations were highest in the groups taking 600 mg and 900 mg NMN. No safety issues, based on monitoring adverse events (AEs), laboratory and clinical measures, were found, and NMN supplementation was well tolerated. ...NMN supplementation incr …
Blood NAD concentrations were highest in the groups taking 600 mg and 900 mg NMN. No safety issues, based on monitoring adverse event …
NAD+ Precursors Nicotinamide Mononucleotide (NMN) and Nicotinamide Riboside (NR): Potential Dietary Contribution to Health.
Alegre GFS, Pastore GM. Alegre GFS, et al. Curr Nutr Rep. 2023 Sep;12(3):445-464. doi: 10.1007/s13668-023-00475-y. Epub 2023 Jun 5. Curr Nutr Rep. 2023. PMID: 37273100 Free PMC article. Review.
RECENT FINDINGS: NMN and NR demonstrated protect against diabetes, Alzheimer disease, endothelial dysfunction, and inflammation. ...NMN and NR can be obtained through the diet either in their free form or as metabolites derivate from the digestion of NAD+. ...
RECENT FINDINGS: NMN and NR demonstrated protect against diabetes, Alzheimer disease, endothelial dysfunction, and inflammation. ... …
The role of nicotinamide mononucleotide (NMN) in anti-aging, longevity, and its potential for treating chronic conditions.
Soma M, Lalam SK. Soma M, et al. Mol Biol Rep. 2022 Oct;49(10):9737-9748. doi: 10.1007/s11033-022-07459-1. Epub 2022 Apr 20. Mol Biol Rep. 2022. PMID: 35441939 Review.
Some of the new studies conducted in mice and humans have targeted the NAD(+) metabolism with NAD(+) intermediates. Of these, nicotinamide mononucleotide (NMN) has been shown to offer great therapeutic potential with promising results in age-related chronic conditions such …
Some of the new studies conducted in mice and humans have targeted the NAD(+) metabolism with NAD(+) intermediates. Of these, nicotinamide m …
Preclinical and clinical evidence of NAD(+) precursors in health, disease, and ageing.
Reiten OK, Wilvang MA, Mitchell SJ, Hu Z, Fang EF. Reiten OK, et al. Mech Ageing Dev. 2021 Oct;199:111567. doi: 10.1016/j.mad.2021.111567. Epub 2021 Sep 10. Mech Ageing Dev. 2021. PMID: 34517020 Free article. Review.
NAD(+) is a fundamental molecule in human life and health as it participates in energy metabolism, cell signalling, mitochondrial homeostasis, and in dictating cell survival or death. ...Major NAD(+) precursors focused on by this review are nicotinamide riboside (NR), nico …
NAD(+) is a fundamental molecule in human life and health as it participates in energy metabolism, cell signalling, mitochondrial hom …
CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD(+) and NMN levels.
Chini CCS, Peclat TR, Warner GM, Kashyap S, Espindola-Netto JM, de Oliveira GC, Gomez LS, Hogan KA, Tarragó MG, Puranik AS, Agorrody G, Thompson KL, Dang K, Clarke S, Childs BG, Kanamori KS, Witte MA, Vidal P, Kirkland AL, De Cecco M, Chellappa K, McReynolds MR, Jankowski C, Tchkonia T, Kirkland JL, Sedivy JM, van Deursen JM, Baker DJ, van Schooten W, Rabinowitz JD, Baur JA, Chini EN. Chini CCS, et al. Nat Metab. 2020 Nov;2(11):1284-1304. doi: 10.1038/s42255-020-00298-z. Epub 2020 Nov 16. Nat Metab. 2020. PMID: 33199925 Free PMC article.
Finally, blocking the ecto-enzymatic activity of CD38 can increase NAD(+) through a nicotinamide mononucleotide (NMN)-dependent process. Our findings demonstrate that senescence-induced inflammation promotes accumulation of CD38 in immune cells that, through its ecto-enzym …
Finally, blocking the ecto-enzymatic activity of CD38 can increase NAD(+) through a nicotinamide mononucleotide (NMN)-dependent proce …
The Safety and Antiaging Effects of Nicotinamide Mononucleotide in Human Clinical Trials: an Update.
Song Q, Zhou X, Xu K, Liu S, Zhu X, Yang J. Song Q, et al. Adv Nutr. 2023 Nov;14(6):1416-1435. doi: 10.1016/j.advnut.2023.08.008. Epub 2023 Aug 22. Adv Nutr. 2023. PMID: 37619764 Free PMC article. Review.
The promotion of NMN as an antiaging health supplement has gained popularity due to such findings; however, since most studies evaluating the effects of NMN have been conducted in cell or animal models, a concern remains regarding the safety and physiological …
The promotion of NMN as an antiaging health supplement has gained popularity due to such findings; however, since most studies …
Nicotinamide mononucleotide (NMN) intake increases plasma NMN and insulin levels in healthy subjects.
Yamane T, Imai M, Bamba T, Uchiyama S. Yamane T, et al. Clin Nutr ESPEN. 2023 Aug;56:83-86. doi: 10.1016/j.clnesp.2023.04.031. Epub 2023 May 5. Clin Nutr ESPEN. 2023. PMID: 37344088 Free article.
An increase in NAD(+) concentration induces SIRT1 activation that results in various health benefits. Since nicotinamide mononucleotide (NMN) is a precursor of NAD(+), NMN ingestion is expected to have multiple health benefits such as alleviation of ag …
An increase in NAD(+) concentration induces SIRT1 activation that results in various health benefits. Since nicotinamide mononucleoti …
Mitochondrial Dysfunction and Therapeutic Perspectives in Cardiovascular Diseases.
Liu Y, Huang Y, Xu C, An P, Luo Y, Jiao L, Luo J, Li Y. Liu Y, et al. Int J Mol Sci. 2022 Dec 16;23(24):16053. doi: 10.3390/ijms232416053. Int J Mol Sci. 2022. PMID: 36555691 Free PMC article. Review.
., supplement with NAD(+), nicotinamide riboside (NR), nicotinamide mononucleotide (NMN), and nano-drug delivery), and reducing ROS (e.g., supplement with Coenzyme Q10 and other antioxidants), and dissected their respective advantages and limitations. ...
., supplement with NAD(+), nicotinamide riboside (NR), nicotinamide mononucleotide (NMN), and nano-drug delivery), and reducing ROS ( …
260 results