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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 9
2002 35
2003 69
2004 78
2005 96
2006 96
2007 136
2008 114
2009 106
2010 124
2011 113
2012 113
2013 116
2014 112
2015 87
2016 94
2017 91
2018 76
2019 71
2020 64
2021 67
2022 59
2023 58
2024 30

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1,811 results

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NOD1 and NOD2 in inflammatory and infectious diseases.
Trindade BC, Chen GY. Trindade BC, et al. Immunol Rev. 2020 Sep;297(1):139-161. doi: 10.1111/imr.12902. Epub 2020 Jul 17. Immunol Rev. 2020. PMID: 32677123 Free PMC article. Review.
Significant advances have been made from efforts that characterize their upstream activators, assembly of signaling complexes, and activation of downstream signaling pathways. Disruption in NOD1 and NOD2 signaling has also been associated with impaired host defense …
Significant advances have been made from efforts that characterize their upstream activators, assembly of signaling complexes, and activatio …
NOD2-associated diseases: Bridging innate immunity and autoinflammation.
Borzutzky A, Fried A, Chou J, Bonilla FA, Kim S, Dedeoglu F. Borzutzky A, et al. Clin Immunol. 2010 Mar;134(3):251-61. doi: 10.1016/j.clim.2009.05.005. Epub 2009 May 24. Clin Immunol. 2010. PMID: 19467619 Review.
Mutations in the gene encoding NOD2 in humans have been associated with Crohn's disease (CD), Blau syndrome (BS), and early onset sarcoidosis (EOS). ...The patient had a susceptibility polymorphism of NOD2 previously described in CD, but not in BS or E …
Mutations in the gene encoding NOD2 in humans have been associated with Crohn's disease (CD), Blau syndrome (BS), and e …
Role and molecular mechanism of NOD2 in chronic non-communicable diseases.
Kong L, Cao Y, He Y, Zhang Y. Kong L, et al. J Mol Med (Berl). 2024 Jun;102(6):787-799. doi: 10.1007/s00109-024-02451-7. Epub 2024 May 14. J Mol Med (Berl). 2024. PMID: 38740600 Review.
Recently, NOD2 has been shown to be associated with the pathogenesis of diabetes, cardiac-cerebral diseases, and cancers. However, the function of NOD2 in these non-communicable diseases (CNCDs) is not well summarized in reviews. ...
Recently, NOD2 has been shown to be associated with the pathogenesis of diabetes, cardiac-cerebral diseases, and cancer …
Implications of combined NOD2 and other gene mutations in autoinflammatory diseases.
Nomani H, Deng Z, Navetta-Modrov B, Yang J, Yun M, Aroniadis O, Gorevic P, Aksentijevich I, Yao Q. Nomani H, et al. Front Immunol. 2023 Oct 19;14:1265404. doi: 10.3389/fimmu.2023.1265404. eCollection 2023. Front Immunol. 2023. PMID: 37928541 Free PMC article.
NOD-like receptors (NLRs) are intracellular sensors associated with systemic autoinflammatory diseases (SAIDs). We investigated the largest monocentric cohort of patients with adult-onset SAIDs for coinheritance of low frequency and rare mutations in NOD2 and …
NOD-like receptors (NLRs) are intracellular sensors associated with systemic autoinflammatory diseases (SAIDs). We investigate …
Granulomatous disease associated with NOD2 sequence variants and familial camptodactyly: An intermediate form of NOD2-associated diseases?
Shen M, Moran R, Tomecki KJ, Yao Q. Shen M, et al. Semin Arthritis Rheum. 2015 Dec;45(3):357-60. doi: 10.1016/j.semarthrit.2015.05.007. Epub 2015 May 21. Semin Arthritis Rheum. 2015. PMID: 26164256
OBJECTIVE: Nucleotide-binding oligomerization domain-containing protein-2 (NOD2)-associated diseases may be a spectrum of disease. We report two families who exhibited an intermediate form of Blau syndrome and NOD2-associated autoinflamma …
OBJECTIVE: Nucleotide-binding oligomerization domain-containing protein-2 (NOD2)-associated diseases may be a spectrum …
SARS-CoV-2/COVID-19 and its relationship with NOD2 and ubiquitination.
Rivera EG, Patnaik A, Salvemini J, Jain S, Lee K, Lozeau D, Yao Q. Rivera EG, et al. Clin Immunol. 2022 May;238:109027. doi: 10.1016/j.clim.2022.109027. Epub 2022 May 2. Clin Immunol. 2022. PMID: 35513305 Free PMC article. Review.
COVID-19 infection partly results from host inborn errors and genetic factors and can lead to autoinflammatory disease. The interaction between defective NOD2 and viral infection may trigger NOD2-associated disease. ...During viral infection, mu …
COVID-19 infection partly results from host inborn errors and genetic factors and can lead to autoinflammatory disease. The interacti …
Macroglobulinemia and Autoinflammatory Disease.
Navetta-Modrov B, Yao Q. Navetta-Modrov B, et al. Rheumatol Immunol Res. 2021 Dec 31;2(4):227-232. doi: 10.2478/rir-2021-0031. eCollection 2021 Dec. Rheumatol Immunol Res. 2021. PMID: 36467983 Free PMC article. Review.
The aim of this article was to review the above-mentioned two diseases from clinical aspects and their potential genetic links. We performed a PubMed search using the following keywords: "SchS," "WM," "autoinflammatory disease," "periodic fever syndrome," and "nucle …
The aim of this article was to review the above-mentioned two diseases from clinical aspects and their potential genetic links. We pe …
A nod to the bond between NOD2 and mycobacteria.
Dubé JY, Behr MA. Dubé JY, et al. PLoS Pathog. 2023 Jun 1;19(6):e1011389. doi: 10.1371/journal.ppat.1011389. eCollection 2023 Jun. PLoS Pathog. 2023. PMID: 37262021 Free PMC article. Review.
NOD2 was linked to mycobacterial infection at 3 levels: (1) genetic, through association with mycobacterial diseases of humans; (2) chemical, through the distinct NOD2 ligand in the mycobacterial cell wall; and (3) immunologic, through heightened NO …
NOD2 was linked to mycobacterial infection at 3 levels: (1) genetic, through association with mycobacterial diseases of …
NOD2 polymorphisms associated with cancer risk: a meta-analysis.
Liu J, He C, Xu Q, Xing C, Yuan Y. Liu J, et al. PLoS One. 2014 Feb 20;9(2):e89340. doi: 10.1371/journal.pone.0089340. eCollection 2014. PLoS One. 2014. PMID: 24586700 Free PMC article.
CONCLUSION: NOD2 rs2066844 C/T, rs2066845 C/G and rs2066847 (3020insC) polymorphisms might be associated with increased cancer risk. No significant association was observed between NOD2 rs2066842 C/T polymorphism and cancer risk. ...
CONCLUSION: NOD2 rs2066844 C/T, rs2066845 C/G and rs2066847 (3020insC) polymorphisms might be associated with increased cancer …
NOD2-associated autoinflammatory disease: a large cohort study.
Yao Q, Shen M, McDonald C, Lacbawan F, Moran R, Shen B. Yao Q, et al. Rheumatology (Oxford). 2015 Oct;54(10):1904-12. doi: 10.1093/rheumatology/kev207. Epub 2015 Jun 11. Rheumatology (Oxford). 2015. PMID: 26070941
OBJECTIVE: The aims of the study were to characterize the genotype profile of nucleotide-binding oligomerization domain containing 2 (NOD2)-associated autoinflammatory disease (NAID) and to report an extended study of the disease. ...CONCLUSION: This s …
OBJECTIVE: The aims of the study were to characterize the genotype profile of nucleotide-binding oligomerization domain containing 2 (NOD …
1,811 results