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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1952 1
1954 1
1965 2
1967 2
1968 1
1969 1
1970 2
1971 5
1972 4
1973 4
1974 4
1975 18
1976 10
1977 12
1978 6
1979 15
1980 11
1981 18
1982 30
1983 28
1984 21
1985 34
1986 28
1987 31
1988 34
1989 27
1990 36
1991 36
1992 28
1993 16
1994 23
1995 33
1996 24
1997 38
1998 35
1999 26
2000 46
2001 40
2002 41
2003 52
2004 59
2005 63
2006 47
2007 40
2008 57
2009 62
2010 70
2011 81
2012 76
2013 96
2014 102
2015 111
2016 120
2017 124
2018 138
2019 155
2020 175
2021 167
2022 238
2023 243
2024 89

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2,835 results

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Page 1
Showing results for novo sterol
Your search for novosterol retrieved no results
Comparative Effects of Low-Dose Rosuvastatin, Placebo, and Dietary Supplements on Lipids and Inflammatory Biomarkers.
Laffin LJ, Bruemmer D, Garcia M, Brennan DM, McErlean E, Jacoby DS, Michos ED, Ridker PM, Wang TY, Watson KE, Hutchinson HG, Nissen SE. Laffin LJ, et al. J Am Coll Cardiol. 2023 Jan 3;81(1):1-12. doi: 10.1016/j.jacc.2022.10.013. Epub 2022 Nov 6. J Am Coll Cardiol. 2023. PMID: 36351465 Free article. Clinical Trial.
Participants were randomized to rosuvastatin 5 mg daily, placebo, fish oil, cinnamon, garlic, turmeric, plant sterols, or red yeast rice. The primary endpoint was the percent change in LDL-C from baseline for rosuvastatin 5 mg daily compared with placebo and each supplemen …
Participants were randomized to rosuvastatin 5 mg daily, placebo, fish oil, cinnamon, garlic, turmeric, plant sterols, or red yeast r …
Sterol regulatory element-binding protein 2 maintains glioblastoma stem cells by keeping the balance between cholesterol biosynthesis and uptake.
Gu D, Zhou F, You H, Gao J, Kang T, Dixit D, Wu Q, Yang K, Ci S, Shan D, Fan X, Yuan W, Zhang Q, Lu C, Li D, Zhao N, Shi Z, Gao W, Lin F, Man J, Wang Q, Qian X, Mack SC, Tao W, Agnihotri S, Zhang N, You Y, Rich JN, Zhang J, Wang X. Gu D, et al. Neuro Oncol. 2023 Sep 5;25(9):1578-1591. doi: 10.1093/neuonc/noad060. Neuro Oncol. 2023. PMID: 36934350 Free PMC article.
Glioblastoma stem cells (GSCs) adapt to regions of heterogeneous nutrient availability, yet display dependency on de novo cholesterol biosynthesis. The transcription factor Sterol Regulatory Element-Binding Protein 2 (SREBP2) regulates cholesterol biosynthesis enzym …
Glioblastoma stem cells (GSCs) adapt to regions of heterogeneous nutrient availability, yet display dependency on de novo cholesterol …
De novo phytosterol synthesis in animals.
Michellod D, Bien T, Birgel D, Violette M, Kleiner M, Fearn S, Zeidler C, Gruber-Vodicka HR, Dubilier N, Liebeke M. Michellod D, et al. Science. 2023 May 5;380(6644):520-526. doi: 10.1126/science.add7830. Epub 2023 May 4. Science. 2023. PMID: 37141360
We show that sitosterol, a common sterol of plants, is the most abundant sterol in gutless marine annelids. Using multiomics, metabolite imaging, heterologous gene expression, and enzyme assays, we show that these animals synthesize sitosterol de novo using a …
We show that sitosterol, a common sterol of plants, is the most abundant sterol in gutless marine annelids. Using multiomics, …
Effect of Calorie-Unrestricted Low-Carbohydrate, High-Fat Diet Versus High-Carbohydrate, Low-Fat Diet on Type 2 Diabetes and Nonalcoholic Fatty Liver Disease : A Randomized Controlled Trial.
Hansen CD, Gram-Kampmann EM, Hansen JK, Hugger MB, Madsen BS, Jensen JM, Olesen S, Torp N, Rasmussen DN, Kjærgaard M, Johansen S, Lindvig KP, Andersen P, Thorhauge KH, Brønd JC, Hermann P, Beck-Nielsen H, Detlefsen S, Hansen T, Højlund K, Thiele MS, Israelsen M, Krag A. Hansen CD, et al. Ann Intern Med. 2023 Jan;176(1):10-21. doi: 10.7326/M22-1787. Epub 2022 Dec 13. Ann Intern Med. 2023. PMID: 36508737 Clinical Trial.
CONCLUSION: Persons with T2DM on a 6-month, calorie-unrestricted, LCHF diet had greater clinically meaningful improvements in glycemic control and weight compared with those on an HCLF diet, but the changes were not sustained 3 months after intervention. PRIMARY FUNDING SOURCE: …
CONCLUSION: Persons with T2DM on a 6-month, calorie-unrestricted, LCHF diet had greater clinically meaningful improvements in glycemic contr …
Hyperoside attenuates non-alcoholic fatty liver disease in rats via cholesterol metabolism and bile acid metabolism.
Wang S, Sheng F, Zou L, Xiao J, Li P. Wang S, et al. J Adv Res. 2021 Jun 8;34:109-122. doi: 10.1016/j.jare.2021.06.001. eCollection 2021 Dec. J Adv Res. 2021. PMID: 35024184 Free PMC article.
The expression of nuclear receptors (NRs), including farnesoid X receptor (FXR) and liver X receptor alpha (LXRalpha), were increased in hyperoside-treated rats' liver tissue, accompanied by decreased protein expression of catalyzing enzymes in the hepatic de novo lipogene …
The expression of nuclear receptors (NRs), including farnesoid X receptor (FXR) and liver X receptor alpha (LXRalpha), were increased in hyp …
A genetic system for Akkermansia muciniphila reveals a role for mucin foraging in gut colonization and host sterol biosynthesis gene expression.
Davey LE, Malkus PN, Villa M, Dolat L, Holmes ZC, Letourneau J, Ansaldo E, David LA, Barton GM, Valdivia RH. Davey LE, et al. Nat Microbiol. 2023 Aug;8(8):1450-1467. doi: 10.1038/s41564-023-01407-w. Epub 2023 Jun 19. Nat Microbiol. 2023. PMID: 37337046
Here we developed and applied transposon mutagenesis to identify genes important for intestinal colonization and for the use of mucin. An analysis of transposon mutants indicated that de novo biosynthesis of amino acids was required for A. muciniphila growth on mucin mediu …
Here we developed and applied transposon mutagenesis to identify genes important for intestinal colonization and for the use of mucin. An an …
Impact of Cholesterol Metabolism in Immune Cell Function and Atherosclerosis.
Aguilar-Ballester M, Herrero-Cervera A, Vinué Á, Martínez-Hervás S, González-Navarro H. Aguilar-Ballester M, et al. Nutrients. 2020 Jul 7;12(7):2021. doi: 10.3390/nu12072021. Nutrients. 2020. PMID: 32645995 Free PMC article. Review.
Cholesterol, the most important sterol in mammals, helps maintain plasma membrane fluidity and is a precursor of bile acids, oxysterols, and steroid hormones. Cholesterol in the body is obtained from the diet or can be de novo synthetized. Cholesterol homeostasis is …
Cholesterol, the most important sterol in mammals, helps maintain plasma membrane fluidity and is a precursor of bile acids, oxystero …
P53 deficiency affects cholesterol esterification to exacerbate hepatocarcinogenesis.
Zhu Y, Gu L, Lin X, Zhou X, Lu B, Liu C, Li Y, Prochownik EV, Karin M, Wang F, Li Y. Zhu Y, et al. Hepatology. 2023 May 1;77(5):1499-1511. doi: 10.1002/hep.32518. Epub 2023 Apr 17. Hepatology. 2023. PMID: 35398929
APPROACH AND RESULTS: Here, we report on a proposed role of tumor suppressor P53 in its repressing ubiquitin-specific peptidase 19 (USP19) and sterol O-acyltransferase (SOAT) 1, which maintains CE homeostasis. ...SOAT1 inhibitor avasimibe has more inhibitory effect on HCC …
APPROACH AND RESULTS: Here, we report on a proposed role of tumor suppressor P53 in its repressing ubiquitin-specific peptidase 19 (USP19) a …
2,835 results